Figure 3 - full size

Figure 3.
Figure 3. (a) and (c) Best-fit backbone superimposition of the 21 lowest overall energy structures of domain 6 (a) and domain1 (c) (generated with MOLMOL[63.]). Helical elements are displayed in red, b-sheet structure is colored in green. (b) and (d) Schematic drawing of a representative structure of domain 6 (b) and domain 1 (d), indicating regular secondary structural elements (same color code as in (a) and (c)). The heavy side-chain atoms of the P1 and P1' residues of domain 6 (Arg383 and Glu384) and the corresponding residues of domain 1 (Gln46 and Asp47) are shown (generated with MOLSCRIPT [65.] and Raster3D [66. and 67.]).