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Figure 3.
Fig. 3. The active sites of the wild-type KAS I, its H298
mutants and their acyl complexes. (A) Wild-type. (B) WT–C8.
(C) Superimposition of the wild-type (white, light colors) and
H298E (orange, dark colors). (D) H298E. (E) H298E–C12. (F)
H298Q. (G) H298Q–C12. (H) Superimposition of H298Q and
H298Q–C12. In (A, B) and (D–G), water molecules (red
spheres) within hydrogen bonding distance are indicated with
dashed lines. (H) Superimposition of H298Q (orange, dark colors)
and H298Q–C12 (white, light colors) not including water
molecules. Figure prepared using PYMOL[42].
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