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Figure 3.
Figure 3 (A) Ribbon representation of the human SHBG dimer
coloured according to the atomic displacement factors
(temperature factors) and model for the packing of the
C-terminal G domains (in grey). The displacement factors range
from 12 (dark blue) to 55 Å^2 (red). (B) Stereo
representation of the steroid-binding pocket in an orientation
identical to that in Figure 2B. All side chains that are in
contact with the steroid are displayed. (C) Chemical structure
and atom numbering in 5  -DHT.
In testosterone, a double bond is present between atoms C4 and
C5. In oestradiol, ring A is aromatic, C19 is missing and the
carbonyl oxygen at C3 is replaced by a hydroxyl group.
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