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Figure 2.
Figure 2: Structure of ASIC1mfc. a, View of the functional
ASIC1mfc trimer. Chloride ions are green spheres. The 'thumb',
'finger' and wrist regions are labelled. Grey bars suggest the
boundaries of the outer (out) and inner (in) leaflets of the
membrane bilayer. b, A vertical slice through a
solvent-accessible surface representation of the transmembrane
domain, the extracellular vestibule and fenestrations. One of
the three equivalent fenestrations is indicated by an arrow. Asp
433 defines the bottom of the extracellular vestibule. c, Key
interactions between symmetry-related Asp 433 carboxyl and Tyr
425 hydroxyl groups.
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