|
Figure 2.
FIGURE 2. Comparison of binding of non-covalent inhibitors
to GlcCerase. A, NN-DNJ/pGlcCerase. B, NB-DNJ/pGlcCerase. C,
IFG/DG-Cerezyme. Green lines represent hydrogen bonds and red
lines hydrophobic interactions. L1, loop 1 (residues 341-350);
L2, loop 2 (residues 393-396); L3, loop 3 (residues 312-319).
314(B) in panel A corresponds to the side chain of a
symmetrically related molecule.
|
