Figure 2 - full size

Figure 2.
Figure 2. Structural comparison of the two RRM domains of Npl3 to each other and to those of SxL protein (PDB 1B7F). (a) Superposition of the structure of RRM-1 (gray) on RRM-2 (orange) shows that the two domains are very similar, with an r.m.s.d. between them of only 1.3 Å, despite the differences in the loop between β2 and β3. (b) Superposition of the RRM-1 domain of Npl3 (gray) with the RRM-1 domain of SxL (blue) gives an r.m.s.d. of only 1.1 Å, while (c) superposition of the RRM-2 domain of Npl3 (orange) with the RRM-2 domain of SxL (green) gives an r.m.s.d. of 1.3 Å. The Figure was generated using PyMOL [http://pymol.sourceforge.net/].