Figure 2 - full size

Figure 2.
(a) ELS4 TCR 'footprint'. Surface representation of HLA-B^*3501 'looking down' into the peptide-binding cleft. HLA-B^*3501, gray; EPLP peptide, dark gray; colors of pMHCI residues that contact the TCR are according to that of the relevant contacting CDR loop (as described in Fig. 1), and peptide residues are identified in red by one-letter amino-acid designation followed by position number. (b) SB27 TCR 'footprint'. Surface representation of HLA-B^*3508 'looking down' into the peptide-binding cleft. HLA-B^*3508, gray; LPEP peptide, dark gray; other colors as described in a.