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Figure 2.
Figure 2. (Upper panel) Relaxed stereodiagram of an overlay of
the turn 1 region in the wild-type FGF-1 structure (light gray)
with that of the  G19
mutant (dark gray). Also shown is a 2F[o] - F[c] difference
electron density map of the G19
mutant contoured at 1.5  .
Turn 1 has converted from type I 4:6 in the wild-type structure
to a type I 3:5 in the G19
mutant. (Middle panel) Relaxed stereodiagram of an overlay of
the turn 5 region in the wild-type FGF-1 structure (light gray)
with that of the E60
mutant (dark gray). Also shown is a 2F[o] - F[c] difference
electron density map of the E60
mutant contoured at 1.5 .
Turn 5 has converted from type I 4:6 in the wild-type structure
to a type I 3:5 in the E60
mutant. (Lower panel) Relaxed stereodiagram of an overlay of the
turn 1 region in the G19
mutant structure (light gray) with that of the S17T/N18T/ G19
mutant (dark gray). Also shown is a 2F[o] - F[c] difference
electron density map of the S17T/N18T/ G19
mutant contoured at 1.5 .
The S17T/N18T mutations in the turn 1 region are accommodated
with essentially no change to the turn structure in the G19
mutant background.
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