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Figure 2.
Fig. 2. Map of DNA structure space sampled by crystals of
d(CCnnnN[6]N[7]N[8]GG). The map is divided into three specific
structural classes (labeled B for B-DNA, A for A-DNA, and J for
junctions) and the interfaces between each conformational phase.
The sequences in uppercase letters define those that have been
uniquely solved or reproduced in the current study, while those
in lowercase letters are structures from previous studies, but
not reproduced here. The rectangle around GCC indicates that the
structure is induced by a change in divalent cations (from Ca^2+
to Mg2+). Similarly, the oval around GGC indicates that the A
form is induced by alcohol. Arrows trace paths through the
conformational map as the N[6]N[7]N[8] trinucleotide undergoes
single-nucleotide transitions or transversions. These are not
unique paths, but show one set of consistent single-nucleotide
steps through the conformational space.
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