Figure 2.
Figure 2. (a) Diagram showing the secondary structure elements
in TM1459 superimposed on its primary sequence. -Hairpins
are depicted as red loops. Residues coordinating the metal ion
are marked with blue dots. (b) The active site of TM1459 showing
the proposed manganese ion (Mn), its coordinating residues
(His52, His54, His58, His92, and two waters) and Cys106,
adjacent to the unidentified density modeled as UNL, is depicted
in ball and stick. The atoms are indicated as follows: carbon
(grey), oxygen (red), nitrogen (blue), sulfur (orange) and
manganese (purple). Metal-ligand bonds are represented as dashed
yellow lines.
-Hairpins
are depicted as red loops. Residues coordinating the metal ion
are marked with blue dots. (b) The active site of TM1459 showing
the proposed manganese ion (Mn), its coordinating residues
(His52, His54, His58, His92, and two waters) and Cys106,
adjacent to the unidentified density modeled as UNL, is depicted
in ball and stick. The atoms are indicated as follows: carbon
(grey), oxygen (red), nitrogen (blue), sulfur (orange) and
manganese (purple). Metal-ligand bonds are represented as dashed
yellow lines.