Figure 2 - full size

Figure 2.
Figure 2. The substrate fragments. The natural substrate of TS, dUMP (1), can be subdivided into several fragments, of which various combinations are commercially available. These include 2'-deoxyuridine (dUrd; 2), 2'5'-dideoxyuridine (ddUrd; 3), uridine (Urd; 4), phosphoribose (PR; 5), and phosphate (PO[4]^2-; 6).