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Figure 2.
Figure 2. (A) Superposition of TM1560 (gray) and invertase
inhibitor Nt-Cif from Tobacco (PDB code: 1rj1, magenta). (B) The
putative active site pocket in surface representation. Residues
are colored according to sequence conservation, where green is
conserved and white is nonconserved. The manually docked ligand
N^5, N^10-methenyltetrahydrofolate (MTHF) is shown in stick
representation (yellow). (C) Same orientation as (B), but shown
in ribbon representation, with conserved residues in the
putative active site of TM1560 and the manually docked MTHF
ligand in stick representation. Monomers 1 and 2 in the dimer
are shown in blue and gray, respectively.
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