Figure 2 - full size

Figure 2.
Fig. 2. Location of -amanitin bound to pol II. (A) Cutaway view of a pol II-transcribing complex showing the location of -amanitin binding (red dot) in relation to the nucleic acids and functional elements of the enzyme. Adapted from ref. 24. (B) Ribbons representation of the pol II structure (top view in refs. 1 and 7). Eight zinc atoms are shown in light blue, the active site magnesium is magenta, the region of Rpb1 around -amanitin is light green (funnel) and dark green (bridge helix), the region of Rpb2 near -amanitin is dark blue, and -amanitin is red. This figure was prepared by using RIBBONS (25).