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Figure 2.
Fig. 2. Location of -amanitin
bound to pol II. (A) Cutaway view of a pol II-transcribing
complex showing the location of -amanitin
binding (red dot) in relation to the nucleic acids and
functional elements of the enzyme. Adapted from ref. 24. (B)
Ribbons representation of the pol II structure (top view in
refs. 1 and 7). Eight zinc atoms are shown in light blue, the
active site magnesium is magenta, the region of Rpb1 around -amanitin
is light green (funnel) and dark green (bridge helix), the
region of Rpb2 near -amanitin
is dark blue, and -amanitin
is red. This figure was prepared by using RIBBONS (25).
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