Figure 2.
Figure 2 The G domain fold in SHBG. (A and B) Ribbon
representation of the N-terminal domain of SHBG in two
orthogonal orientations. The -strands
of the two sheets forming a -sandwich
are coloured in yellow and blue, respectively. The steroid 5
-DHT
is shown in a ball and stick representation. The segment
130–135, which is expected to loop over the steroid-binding
pocket, is disordered and not visible in the electron density.
The calcium ion is shown as a green dot (figures generated with
MOLSCRIPT and RASTER3D; Kraulis, 1991; Merritt and Murphy,
1994). (C) Topology diagram of the -strands.
Triangles pointing upwards denote -strands
pointing out of the paper plane. The conserved disulfide bond
between residues 164 and 188 is indicated as a dashed line.
-strands
of the two sheets forming a 
-DHT
is shown in a ball and stick representation. The segment
130–135, which is expected to loop over the steroid-binding
pocket, is disordered and not visible in the electron density.
The calcium ion is shown as a green dot (figures generated with
MOLSCRIPT and RASTER3D; Kraulis, 1991; Merritt and Murphy,
1994). (C) Topology diagram of the