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Figure 1.
Figure 1. Schematic Representation of the ATP Binding Site
in KinasesATP (in ball-and-sticks) interacts mainly with the
linker/adenine binding region (1), the ribose binding region
(2), and the phosphate binding region (3). The two hydrophobic
regions I (4) and II (5) do not directly interact with ATP and
contain residues that vary among kinases, thus providing
possibilities for the development of selective inhibitors [17].
Figures 1, 2B, and 3–6 were made with RIBBONS [42].
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