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Figure 1.
Figure 1: Overall structure of the plasma membrane H^+-ATPase.
The structure represents an active form of the proton pump,
without its auto-inhibitory C terminus, in complex with
Mg-AMPPCP. Ten transmembrane helices, orange, green and brown,
as indicated; nucleotide-binding domain (N), red; the
phosphorylation domain (P), blue; and the actuator domain (A),
yellow. Mg-AMPPCP is found at the interface between the N and P
domains and is shown as a ball-and-stick reprentation. Key
residues mentioned in the text are shown as sticks. The grey box
depicts the approximate location of the plasma membrane.
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