Figure 1.
FIGURE 1. Crystal structure of WNV POL1 and comparison with
HCV RdRp. A, stereo view of a ribbon representation of WNV POL1
in its front orientation. The palm, thumb, and fingers domains
and the priming loop are colored in green, red, dark blue, and
purple, respectively. -Helices and -sheets
are indicated. Insertions in WNV POL1 compared with HCV RdRp are
displayed in yellow, and major structural differences are shown
in orange. These and other figures were prepared with PyMOL. B,
ribbon representation of HCV RdRp in its front orientation (50)
(PDB code 1NB6). The color code is the same as in A. Insertions
in HCV RdRp compared with WNV are colored in yellow.
-Helices and 
-sheets
are indicated. Insertions in WNV POL1 compared with HCV RdRp are
displayed in yellow, and major structural differences are shown
in orange. These and other figures were prepared with PyMOL. B,
ribbon representation of HCV RdRp in its front orientation (50)
(PDB code 1NB6). The color code is the same as in A. Insertions
in HCV RdRp compared with WNV are colored in yellow.