Figure 1 - full size

Figure 1.
Figure 1. Hoogsteen pairing of dA with T or C. (a) Chemical structures of A and dA. (b) Hoogsteen base pair of syn-A in syn with anti-T or anti-C. Jagged line represents steric clash between the N6 group of A and the N4 of C. (c) Hoogsteen base pair of dA with T or C. Dotted lines represent hydrogen bonds and R denotes the sugar moiety.