|
Figure 1.
Figure 1. Structures of PDZ Domains
(A) Overlay of the
ensemble of 35 NMR-derived structures of the PDZ2-peptide
complex colored as a rainbow ramp ranging from blue (N terminus)
to red (C terminus). The peptide is shown in stick
representation. For clarity, only the last five C-terminal
residues of the peptide are displayed.
(B) Superposition of
the structures of PDZ2 in the free (green, helix α2 in pink,
PDB code 1GM1) and complexed (blue, helix α2 in cyan, peptide
in red) states.
(C) Superposition between the structures of
PDZ3 in the free and complexed states (PDB codes 1BFE and 1BE9,
respectively). Color coding as in (B).
|
