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Figure 1.
Figure 1. The Proximal N Terminus of Kv4.2 Is Necessary for
Modulation by KChIP1Currents were recorded from oocytes injected
with the indicated Kv4.2 wild-type or deletion mutant RNA in the
presence or absence of KChIP1. The left side panels depict
representative current traces measured at +50 mV for 1 s from
holding potential at −80 mV, and the right side of each panel
depicts normalized recovery from inactivation fitted with a
single exponential function for Kv4.2 alone (open circle) and
for Kv4.2 co-expressed with KChIP1 (closed circle).(A) Wild-type
Kv4.2; (B) Kv4.2Δ2–21; (C) Kv4.2Δ2–11; (D) Kv4.2Δ2–6;
(E) Kv4.2Δ7–11; (F) Kv4.2(WGEFA) multiple point mutant,
contains mutations in Kv4.2 7–11 region.
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