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Figure 1.
Figure 1. Crystal structure of TM0920. A: Ribbon diagram of
Thermotoga maritima TM0920 1,3-propanediol dehydrogenase color
coded from N-terminus (blue) to C-terminus (red) showing the
domain organization and location of the active site (arrow).
-helices
(H1-H19) and -strands
( 1-
8)
are indicated. The NADP^+ molecule is shown in ball and stick.
The Fe^2+ ion is shown as a sphere in magenta. B: Diagram
showing the secondary structure elements in TM0920 superimposed
on its primary sequence. Residues located in the active site and
interacting with Fe^2+ are indicated by blue dots and green
triangles. Residues interacting with NADP^+ are indicated by red
dots. The location of the -hairpin
formed by -strands
6 and 7 is depicted in red.
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