Figure 1 - full size

Figure 1.
Figure 1. Crystal structure of TM0920. A: Ribbon diagram of Thermotoga maritima TM0920 1,3-propanediol dehydrogenase color coded from N-terminus (blue) to C-terminus (red) showing the domain organization and location of the active site (arrow). -helices (H1-H19) and -strands ( 1- 8) are indicated. The NADP^+ molecule is shown in ball and stick. The Fe^2+ ion is shown as a sphere in magenta. B: Diagram showing the secondary structure elements in TM0920 superimposed on its primary sequence. Residues located in the active site and interacting with Fe^2+ are indicated by blue dots and green triangles. Residues interacting with NADP^+ are indicated by red dots. The location of the -hairpin formed by -strands 6 and 7 is depicted in red.