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Figure 1.
Fig 1. (A) Bacillibactin NRPS cluster from B. subtilis with
the corresponding domain organization of synthetase modules.
ICL, isochorismatase; C, condensation domain; T, thiolation
domain. (B) Structure of the trilactone Bacillibactin, with one
of the catecholic moiety activated by DhbE shaded in gray. (C)
The DhbE-dependent aryl acid adenylation in peptide synthesis is
an ATP-consuming process leading to a protein-bound adenylate.
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