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Figure 1.
Figure 1. Experimental Evidence for DPF, DPW, and FxDxF
Motif Peptides Binding to the a-Ear(A) Ribbon representation of
the a-ear showing the binding sites of the FxDxF (extended
platform site) and DPW2 (distal site) peptides, with the
peptides shown as CPK models.(B-E) The fit of each peptide to
its corresponding simulated annealing omit electron density
contoured at 2.5 s.(B) The FxDxF peptide at 2.15 Å
resolution.(C) The DPF peptide (in P2[1]) at 1.22 Å
resolution.(D) The DPW1 peptide at 2.0 Å resolution.(E) The DPW2
peptide at 2.0 Å resolution. The orientation of the peptides
depicted in B, C, and D were achieved by superposition of the
a-ear platform domain. For the DPW2 peptide in (E), the Ca
coordinates were aligned with those of the DPF peptide. DPF,
cyan; DPW1, steel blue; DPW2, blue-green; FxDxF, magenta.
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