Figure 1 - full size

Figure 1.
Fig. 1. Fold and arrangement of SCR domains in CD55[34]. This figure was drawn using AESOP (M. E. M. Noble, unpublished program). A, secondary structure and location of disulfide bonds in CD55[34]. Strands are labeled according to the convention defined by Norman et al. (35). Note that there is no strand 1 as the hydrogen-bonding pattern of these residues does not meet the strict criteria for definition of a -strand. B, variation in orientation between SCR domains 3 and 4 in the five independent copies of CD55[34] found in the different crystal forms (Table I). C, model for topology of CD55 in the membrane based on our structure of CD55[34].