Figure 1 - full size

Figure 1.
Figure 1. The Structure of Gelsolin(A) Schematic representations of the six domains of gelsolin in similar orientations. A standard coloring of the segments is used here and in subsequent figures: S1, red; S2, light green; S3, yellow; S4, pink; S5, dark green; and S6, orange.(B) The relative organization of S1–S3 and S4–S6. The schematic representation shows S1–S3 (upper panel) and S4–S6 (lower panel) in approximately the same orientation. Linker regions are striped with the colors of the linked segments.(C) Schematic representations of the structure of whole gelsolin. The upper panel shows a view rotated by 90° clockwise around the horizontal with respect to the lower panel. The C-terminal extension is striped orange and black.