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Figure 1.
Fig. 1. Scheme of the primary structure of  1(V) chain
and design of recombinant fragments. 1TH
corresponds to the recombinant triple helical 1(V) COL1
domain overexpressed in mammalian cells (14), HepV corresponds
to a portion of the COL1 domain of the 1(V) chain
produced in E. coli, and the synthetic peptide HepP to a portion
of HepV (the arrow indicates the endoproteinase Glu-C cleavage
site, according to Yaoi et al. (15). COL, collagenous domain;
NC, non-collagenous domain; numbers at the beginning and end of
each fragments refer to amino acid residues.
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