Figure 1 - full size

Figure 1. Fig. 1. A, the final 2F[o] F[c] map overlaid on the models of IGP and residues Glu49 and Tyr175 in the D60N-IGP complex. The map was contoured at 0.6 . B, superposition between IGP (open circles) in the D60N-IGP and IPP (filled circles) in the K87T-Ser-IPP complex (7). The carboxylate of Asp60 is shown near the indole nitrogen of IPP and of IGP.