_EC 3.6.4.12 Dna helicase. 559 PDB entries  
EC 3.-.-.- Hydrolases. [51,952 PDB entries]
EC 3.6.-.- Acting on acid anhydrides. [9,123 PDB entries]
EC 3.6.4.- Acting on ATP; involved in cellular and subcellular movement. [3,249 PDB entries]
EC 3.6.4.12 Dna helicase. [559 PDB entries]
1cr0

Reaction: Atp + H2O = adp + phosphate + H(+).
 


ATP
+ H2O
=
ADP
+
phosphate
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: Dna helicases utilize the energy from atp hydrolysis to unwind double-stranded Dna. Some of them unwind duplex Dna with a 3' to 5' polarity, other show 5' to 3' polarity or unwind Dna in both directions. Some helicases unwind Dna as well as rna. May be identical with Ec 3.6.4.13.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 559 PDB entries in enzyme class E.C.3.6.4.12

  PDB code Protein
1cr0
Crystal structure of the helicase domain of the gene4 protein of bacteriophage t7
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (242 residues) CATH domain: 3.40.50.300
1cr1
Crystal structure of the helicase domain of the gene 4 protein of bacteriophage t7: complex with dttp
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (245 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
1cr2
Crystal structure of the helicase domain of the gene 4 protein of bacteriophage t7: complex with datp
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (239 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group DTP is 96.77% similar to enzyme reactant ATP
1cr4
Crystal structure of the helicase domain of the gene 4 protein of bacteriophage t7: complex with dtdp
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (243 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group TYD is 73.33% similar to enzyme product ADP
1e0j
Gp4d helicase from phage t7 adpnp complex
Source: Phage t7. Organism_taxid: 10760. Gene: gene 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (287 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
1e0k
Gp4d helicase from phage t7
Source: Phage t7. Organism_taxid: 10760. Gene: gene 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (288 residues) CATH domain: 3.40.50.300
1ka8
Crystal structure of the phage p4 origin-binding domain
Source: Enterobacteria phage p4. Organism_taxid: 10680. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (100 residues) CATH domain: 1.10.10.10
1ltl
The dodecamer structure of mcm from archaeal m. Thermoautotrophicum
Source: Methanothermobacter thermautotrophicus. Organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (239 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
1lvo
Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1mbm
Nsp4 proteinase from equine arteritis virus
Source: Equine arteritis virus. Organism_taxid: 11047. Gene: nsp4. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (198 residues) CATH domains: 2.40.10.10 2.40.10.10 3.30.40.20
1msz
Solution structure of the r3h domain from human smubp-2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: smubp-2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (62 residues) CATH domain: 3.30.1370.50
1nui
Crystal structure of the primase fragment of bacteriophage t7 primase- helicase protein
Source: Enterobacteria phage t7. Organism_taxid: 10760. Gene: 4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (242 residues) CATH domain: 2.20.25.10
1p4d
F factor trai relaxase domain
Source: Escherichia coli. Organism_taxid: 562. Gene: trai. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (275 residues) CATH domains: Unassigned 6.10.250.110
1p9u
Coronavirus main proteinase (3clpro) structure: basis for design of anti-sars drugs
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: substrate-analog
Chains: A, B, C, D, E, F (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1q57
The crystal structure of the bifunctional primase-helicase of bacteriophage t7
Source: Enterobacteria phage t7. Organism_taxid: 10760. Gene: 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G (483 residues) CATH domains: Unassigned 3.40.50.300
1s9h
Crystal structure of adeno-associated virus type 2 rep40
Source: Adeno-associated virus - 2. Organism_taxid: 10804. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (268 residues) CATH domains: 1.10.10.950 3.40.50.300
1u0j
Crystal structure of aav2 rep40-adp complex
Source: Adeno-associated virus - 2. Organism_taxid: 10804. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domains: 1.10.10.950 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1z3i
Structure of the swi2/snf2 chromatin remodeling domain of eukaryotic rad54
Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chain: X (644 residues) CATH domains: 3.40.50.10810 3.40.50.300 1.20.120.850
2a0i
F factor trai relaxase domain bound to f orit single-stranded DNA
Source: Synthetic: yes. Other_details: synthesized oligonucleotide. Escherichia coli. Organism_taxid: 562. Gene: trai. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (293 residues)
2c9o
3d structure of the human ruvb-like helicase ruvbl1
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (398 residues) CATH domains: 3.40.50.300 2.40.50.360 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2cqa
Solution structure of rsgi ruh-039, a fragment of c-terminal domain of ruvb-like 2 from human cdna
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl2, tip48, tip49b. Other_details: cell-free protein synthesis
Chain: A (95 residues) CATH domain: 2.40.50.360
2gjk
Structural and functional insights into the human upf1 helicase core
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (614 residues) CATH domains: 3.40.50.300 2.40.30.230 6.10.140.1240 3.40.50.300
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
2gk6
Structural and functional insights into the human upf1 helicase core
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (602 residues) CATH domains: 3.40.50.300 2.40.30.230 6.10.140.1240 3.40.50.300
Bound ligands:   Het Group ADP corresponds to enzyme product ADP
  Het Group PO4 corresponds to enzyme product phosphate
2gk7
Structural and functional insights into the human upf1 helicase core
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (596 residues) CATH domains: 3.40.50.300 2.40.30.230 6.10.140.1240 3.40.50.300
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2gth
Crystal structure of the wildtype mhv coronavirus non-structural protein nsp15
Source: Murine hepatitis virus. Organism_taxid: 11142. Strain: a59. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (348 residues) CATH domains: 3.30.160.820 3.40.50.11580
2gti
Mutation of mhv coronavirus non-structural protein nsp15 (f307l)
Source: Murine hepatitis virus. Organism_taxid: 11142. Strain: a59. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (348 residues) CATH domains: 3.30.160.820 3.40.50.11580
2iyk
Crystal structure of the upf2-interacting domain of nonsense mediated mRNA decay factor upf1
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (155 residues)
2j97
Human coronavirus 229e non structural protein 9 (nsp9)
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (98 residues) CATH domain: 2.40.10.250
2j98
Human coronavirus 229e non structural protein 9 cys69ala mutant (nsp9)
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B (106 residues) CATH domain: 2.40.10.250
2jm1
Structures and chemical shift assignments for the add domain of the atrx protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (141 residues)
2klq
The solution structure of cbd of human mcm6
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (114 residues) CATH domain: 1.20.58.870
2l8b
Trai (381-569)
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: ecok12f104, trai. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (189 residues)
2l8k
Nmr structure of the arterivirus nonstructural protein 7 alpha (nsp7 alpha)
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (123 residues) CATH domain: 3.30.1330.220
2lbm
Solution structure of the add domain of atrx complexed with histone tail h3 1-15 k9me3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide
Chain: A (142 residues)
2ld1
Structures and chemical shift assignments for the add domain of the atrx protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (142 residues)
2le8
The protein complex for DNA replication
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cdt1.
Chain: A (114 residues) CATH domain: 1.20.58.870
2lrr
Solution structure of the r3h domain from human smubp-2 in complex with 2'-deoxyguanosine-5'-monophosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ighmbp2, smbp2, smubp-2, smubp2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (70 residues) CATH domain: 3.30.1370.50
Bound ligand:   Het Group DGP is 78.57% similar to enzyme product ADP
2m45
Nmr solution structure of thE C-terminus of the minichromosome maintenance protein mcm from sulfolobus solfataricus
Source: Sulfolobus solfataricus. Organism_taxid: 273057. Strain: atcc 35092. Gene: mcm, sso0774. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (87 residues) CATH domain: 1.10.10.10
2ma3
Nmr solution structure of thE C-terminus of the minichromosome maintenance protein mcm from methanothermobacter thermautotrophicus
Source: Methanothermobacter thermautotrophicus. Organism_taxid: 145262. Strain: atcc 29096. Gene: mth_1770. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (88 residues) CATH domain: 1.10.10.10
2n16
Solution structure of g-quadruplex recognition domain of rhau
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dhx36, ddx36, kiaa1488, mlel1, rhau. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (20 residues)
2n21
Solution structure of complex between DNA g-quadruplex and g- quadruplex recognition domain of rhau
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dhx36, ddx36, kiaa1488, mlel1, rhau. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chain: A (20 residues)
2q6d
Crystal structure of infectious bronchitis virus (ibv) main protease
Source: Infectious bronchitis virus. Organism_taxid: 11120. Strain: m41. Gene: m41 3c-like protease gene. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C (296 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2q7t
Crystal structure of the f plasmid trai relaxase domain with the scissile thymidine base
Source: Escherichia coli. Gene: trai. Expressed in: escherichia coli.
Chains: A, B (267 residues) CATH domains: Unassigned 6.10.250.110
Bound ligand:   Het Group TMP is 56.00% similar to enzyme product ADP
2q7u
Crystal structure of the f plasmid trai relaxase domain with the scissile thymidine base and imidodiphosphate
Source: Escherichia coli. Strain: trai. Gene: trai. Expressed in: escherichia coli.
Chains: A, B (268 residues) CATH domains: Unassigned 6.10.250.110
Bound ligands:   Het Group TMP is 56.00% similar to enzyme product ADP
  Het Group PON is 66.00% similar to enzyme product phosphate
2vl6
Structural analysis of the sulfolobus solfataricus mcm protein n- terminal domain
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Atcc: 35092. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chains: A, B, C (259 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
2vl7
Structure of s. Tokodaii xpd4
Source: Sulfolobus tokodaii. Organism_taxid: 111955. Strain: 7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (459 residues) CATH domains: 3.40.50.300 1.10.275.30 3.40.50.300
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2wjv
Crystal structure of the complex between human nonsense mediated decay factors upf1 and upf2
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (772 residues) CATH domains: Unassigned 3.40.50.300 2.40.30.230 6.10.140.1240 3.40.50.300
2wjy
Crystal structure of the complex between human nonsense mediated decay factors upf1 and upf2 orthorhombic form
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (773 residues) CATH domains: Unassigned 3.40.50.300 2.40.30.230 6.10.140.1240 3.40.50.300
2xsz
The dodecameric human ruvbl1:ruvbl2 complex with truncated domains ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (318 residues) CATH domains: 3.40.50.300 1.10.8.60
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
2xzl
Upf1-RNA complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chain: A (756 residues) CATH domains: Unassigned 2.40.30.230 3.40.50.300 6.10.140.1240 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2xzo
Upf1 helicase - RNA complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chain: A (613 residues) CATH domains: 3.40.50.300 2.40.30.230 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2xzp
Upf1 helicase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold plyss.
Chain: A (621 residues) CATH domains: 3.40.50.300 2.40.30.230 6.10.140.1240 3.40.50.300
2yrn
Solution structure of the ch domain from human neuron navigator 2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nav2. Other_details: cell-free protein synthesis
Chain: A (129 residues) CATH domain: 1.10.418.10
3ejf
Crystal structure of ibv x-domain at ph 8.5
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11120. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (166 residues) CATH domain: 3.40.220.10
3ejg
Crystal structure of hcov-229e x-domain
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (165 residues) CATH domain: 3.40.220.10
3eke
Crystal structure of ibv x-domain at ph 5.6
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11122. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (171 residues) CATH domain: 3.40.220.10
3eti
Structure of a cubic crystal form of x (adrp) domain from fcov
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (168 residues) CATH domain: 3.40.220.10
3ew5
Structure of the tetragonal crystal form of x (adrp) domain from fcov
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C (168 residues) CATH domain: 3.40.220.10
Bound ligand:   Het Group 1GP is 50.00% similar to enzyme product phosphate
3f9v
Crystal structure of a near full-length archaeal mcm: functional insights for an aaa+ hexameric helicase
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Strain: p2. Gene: mcm, sso0774. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (595 residues)
3fld
Crystal structure of the trai c-terminal domain
Source: Escherichia coli k-12. Organism_taxid: 83333. Strain: k12. Gene: ecok12f104, trai. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (152 residues) CATH domain: Unassigned
3gzf
Structure of thE C-terminal domain of nsp4 from feline coronavirus
Source: Feline coronavirus. Organism_taxid: 12663. Strain: fipv wsu-79. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E (96 residues) CATH domain: 1.10.150.420
3ja8
Cryo-em structure of the mcm2-7 double hexamer
Source: Saccharomyces cerevisiae s288c. Yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
Chains: 2, 3, 4, 5, 6, 7 (603 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3jc5
Structure of the eukaryotic replicative cmg helicase and pumpjack motion
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23. Gene: mcm4, cdc54, hcd21, ypr019w, yp9531.13. Gene: mcm5, cdc46, ylr274w, l9328.1.
Chains: 2, 3, 4, 5, 6, 7 (584 residues)
3jc6
Structure of the eukaryotic replicative cmg helicase and pumpjack motion
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23. Gene: mcm4, cdc54, hcd21, ypr019w, yp9531.13. Gene: mcm5, cdc46, ylr274w, l9328.1.
Chains: 2, 3, 4, 5, 6, 7 (241 residues) CATH domain: 3.30.1640.10
3jc7
Structure of the eukaryotic replicative cmg helicase and pumpjack motion
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23. Gene: mcm4, cdc54, hcd21, ypr019w, yp9531.13. Gene: mcm5, cdc46, ylr274w, l9328.1.
Chains: 2, 3, 4, 5, 6, 7 (576 residues)
3jzt
Structure of a cubic crystal form of x (adrp) domain from fcov with adp-ribose
Source: Feline coronavirus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (168 residues) CATH domain: 3.40.220.10
Bound ligand:   Het Group APR is 75.00% similar to enzyme product ADP
3q90
Crystal structure of the ntf2 domain of ras gtpase-activating protein- binding protein 1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp, g3bp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (121 residues) CATH domain: 3.10.450.50
3ql9
Monoclinic complex structure of atrx add bound to histone h3k9me3 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
Chain: A (125 residues)
3qla
Hexagonal complex structure of atrx add bound to h3k9me3 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
Chains: A, D (127 residues)
3qlc
Complex structure of atrx add domain bound to unmodified h3 1-15 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
Chains: A, B (127 residues)
3qln
Crystal structure of atrx add domain in free state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (123 residues)
3ub0
Crystal structure of the nonstructural protein 7 and 8 complex of feline coronavirus
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (190 residues) CATH domains: Unassigned Unassigned
3uk6
Crystal structure of the tip48 (tip49b) hexamer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cgi-46, ino80j, ruvbl2, tip48, tip49b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (298 residues) CATH domains: 3.40.50.300 1.10.8.60
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3vc8
Crystal structure of thE C-terminal cytoplasmic domain of non- structural protein 4 from mouse hepatitis virus a59
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (81 residues) CATH domain: 1.10.150.420
3vcb
C425s mutant of thE C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus a59
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (89 residues) CATH domain: 1.10.150.420
3wrn
Minute virus of mice non-structural protein-1n-terminal nuclease domain reveals a unique zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Source: Murine minute virus. Mvm. Organism_taxid: 648235. Strain: mvm prototype. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues)
3wro
Minute virus of mice non-structural protein-1n-terminal nuclease domain reveals a unique zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Source: Murine minute virus. Mvm. Organism_taxid: 648235. Strain: mvm prototype. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues)
3wrq
Minute virus of mice non-structural protein-1n-terminal nuclease domain reveals a unique zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Source: Murine minute virus. Mvm. Organism_taxid: 648235. Strain: mvm prototype. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues)
3wrr
Minute virus of mice non-structural protein-1n-terminal nuclease domain reveals a unique zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Source: Murine minute virus. Mvm. Organism_taxid: 648235. Strain: mvm prototype. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues)
3wrs
Minute virus of mice non-structural protein-1n-terminal nuclease domain reveals a unique zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Source: Murine minute virus. Mvm. Organism_taxid: 648235. Strain: mvm prototype. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues)
4b3f
Crystal structure of ighmbp2 helicase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: X (625 residues) CATH domains: 3.40.50.300 2.40.30.270 3.40.50.300
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
4b3g
Crystal structure of ighmbp2 helicase in complex with RNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta. Synthetic: yes
Chains: A, B (614 residues) CATH domains: 3.40.50.300 2.40.30.270 3.40.50.300
4fcj
Crystal structure of the ntf2-like domain of human g3bp1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (128 residues) CATH domain: 3.10.450.50
4fcm
Crystal structure of the ntf2-like domain of human g3bp1 in complex with a peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (132 residues) CATH domain: 3.10.450.50
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
4fdg
Crystal structure of an archaeal mcm filament
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Strain: p2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: B, A, C, D, E (592 residues)
4iia
Low resolution crystal structure of the ntf2-like domain of human g3bp1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (131 residues) CATH domain: 3.10.450.50
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
4ium
Equine arteritis virus papain-like protease 2 (plp2) covalently bound to ubiquitin
Source: Equine arteritis virus. Eav. Organism_taxid: 11047. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chain: A (127 residues) CATH domain: 3.90.70.160
4kw3
Crystal structure of the non-structural protein 1 n-terminal origin- recognition/nickase domain from the emerging human bocavirus
Source: Human bocavirus. Organism_taxid: 329641. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (266 residues) CATH domain: 3.40.1310.20
4m6b
Crystal structure of yeast swr1-z domain in complex with h2a.Z-h2b dimer
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: htb1, h2b1, spt12, ydr224c, yd9934.09c, htz1, h2az, hta3, yol012c, o2345. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: swr1, ydr334w, d9651.6.
Chains: C, F (23 residues)
4me3
1.8 angstrom crystal structure of the n-terminal domain of an archaeal mcm
Source: Thermoplasma acidophilum. Organism_taxid: 2303. Gene: ta0799. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (246 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
4n0n
Crystal structure of arterivirus nonstructural protein 10 (helicase)
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (401 residues)
4n0o
Complex structure of arterivirus nonstructural protein 10 (helicase) with DNA
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, C, E, G (395 residues)
4p16
Crystal structure of the papain-like protease of middle-east respiratory syndrome coronavirus
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: e.Coli-k.Pastoris shuttle vector pppb1gap. Expression_system_taxid: 1182033
Chain: A (315 residues) CATH domains: 3.10.20.540 1.10.8.1190 2.60.120.1680
4pof
Pfmcm n-terminal domain without DNA
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: cdc21, pf0482. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (255 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
4pog
Mcm-ssdna co-crystal structure
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: cdc21, pf0482. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B, C, D, E, F, G, H, I, J, K, L (255 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
4pp4
Minute virus of mice non-structural protein-1n-terminal nuclease domain reveals a unique zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Source: Murine minute virus. Mvm. Organism_taxid: 648235. Strain: mvm prototype. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues)
4r7y
Crystal structure of an active mcm hexamer
Source: Sulfolobus solfataricus, pyrococcus furiosus. Organism_taxid: 273057, 186497. Strain: atcc 35092 / dsm 1617 / jcm 11322 / p2, atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: mcm, sso0774, pf0482. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (591 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
4r7z
Pfmcm-aaa double-octamer
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: mcm, pf0482. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P (316 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
4r94
Structure of the nickase domain of ns1 from mvm complexed with magnesium
Source: Murine minute virus. Mvm. Organism_taxid: 648235. Strain: mvm prototype. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues)
4rez
Crystal structure of the middle-east respiratory syndrome coronavirus papain-like protease
Source: Human betacoronavirus 2c jordan-n3/2012. Organism_taxid: 1306931. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (311 residues) CATH domains: 3.10.20.540 1.10.8.1190 2.60.120.1680
4rf0
Crystal structure of the middle-east respiratory syndrome coronavirus papain-like protease in complex with ubiquitin (space group p6522)
Source: Human betacoronavirus 2c jordan-n3/2012. Organism_taxid: 1306931. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2.
Chain: A (318 residues) CATH domains: 3.10.20.540 1.10.8.1190 2.60.120.1680
4rf1
Crystal structure of the middle-east respiratory syndrome coronavirus papain-like protease in complex with ubiquitin (space group p63)
Source: Human betacoronavirus 2c jordan-n3/2012. Organism_taxid: 1306931. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: uba52, ubcep2.
Chain: A (319 residues) CATH domains: 3.10.20.540 1.10.8.1190 2.60.120.1680
4rs4
Crystal structure and mutational analysis of the endoribonuclease from human coronavirus 229e
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (341 residues) CATH domains: 3.30.160.820 3.40.50.11580
4s1t
Crystal structure of the mutant i26a/n52a of the endoribonuclease from human coronavirus 229e
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (342 residues) CATH domains: 3.30.160.820 3.40.50.11580
4uuz
Mcm2-histone complex
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: lemo21. Homo sapiens. Human. Organism_taxid: 9606.
Chain: C (54 residues)
4v1n
Architecture of the RNA polymerase ii-mediator core transcription initiation complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: bj5464 rpb3 his-bio. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chain: R (105 residues)
4v1o
Architecture of the RNA polymerase ii-mediator core transcription initiation complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: bj5464 rpb3 his-bio. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chain: R (105 residues)
4w5a
Complex structure of atrx add bound to h3k9me3s10ph peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
Chains: A, B, E (128 residues)
4wur
The crystal structure of the mers-cov papain-like protease (c111s) with human ubiquitin
Source: Human coronavirus emc. Hcov-emc. Organism_taxid: 1263720. Strain: isolate united kingdom/h123990006/2012. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: tuner placi. Homo sapiens.
Chain: A (317 residues) CATH domains: 3.10.20.540 1.10.8.1190 2.60.120.1680
4wvy
Double-heterohexameric rings of full-length rvb1(atp)/rvb2(apo)
Source: Chaetomium thermophilum. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Gene: ctht_0006820. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta 2. Gene: ctht_0006170.
Chains: A, B (427 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
4ww4
Double-heterohexameric rings of full-length rvb1(adp)/rvb2(adp)
Source: Chaetomium thermophilum. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Gene: ctht_0006820. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta2. Gene: ctht_0006170. Expression_system_variant: rosetta2
Chains: A, B (416 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
4x0p
Ternary complex of human DNA polymerase theta c-terminal domain binding ddatp opposite a tetrahydrofuran ap site analog
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chains: A, B, C, D (625 residues)
4x0q
Ternary complex of human DNA polymerase theta c-terminal domain binding ddgtp opposite dcmp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chains: A, B (625 residues)
4x2z
Structural view and substrate specificity of papain-like protease from avian infectious bronchitis virus
Source: Avian infectious bronchitis virus. Ibv. Organism_taxid: 11122. Strain: beaudette. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (301 residues)
4xfq
Crystal structure basis for pedv 3c like protease
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: pol1. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (298 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4yo9
Hku4 3clpro unbound structure
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4yog
Hku4-3clpro bound to non-covalent inhibitor 3b
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4yoi
Structure of hku4 3clpro bound to non-covalent inhibitor 1a
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4yoj
Hku4 3clpro bound to non-covalent inhibitor 2a
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4ypt
X-ray structural of three tandemly linked domains of nsp3 from murine hepatitis virus at 2.60 angstroms resolution
Source: Murine coronavirus (strain a59). Mhv-a59. Organism_taxid: 11142. Strain: a59. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (378 residues)
4ywk
Pyrococcus furiosus mcm n-terminal domain with zinc-binding subdomain b deleted
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: pf0482. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (184 residues) CATH domains: 3.30.1640.10 2.40.50.140
4ywl
Pyrococcus furiosus mcm n-terminal domain f179a point mutant pentameric ring
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: pf0482. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J (254 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
4ywm
Pyrococcus furiosus mcm n-terminal domain beta-turn triple mutant pentameric ring
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: pf0482. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J (255 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
4zo0
X-ray structure of aav-2 origin binding domain
Source: Adeno-associated virus 2 (isolate srivastava/1982). Aav-2. Organism_taxid: 648242. Strain: isolate srivastava/1982. Gene: rep68. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
Chains: A, B, C (202 residues) CATH domain: 3.40.1310.20
4zq9
X-ray structure of aav-2 obd bound to aavs1 site 3:1
Source: Adeno-associated virus 2 (isolate srivastava/1982). Aav-2. Organism_taxid: 648242. Strain: isolate srivastava/1982. Gene: rep68. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes.
Chains: A, B, C (185 residues) CATH domain: 3.40.1310.20
4zro
2.1 a x-ray structure of fipv-3clpro bound to covalent inhibitor
Source: Feline coronavirus (strain fipv wsu-79/1146). Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct.
Chains: A, B, C, D (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4zuh
Complex structure of pedv 3clpro mutant (c144a) with a peptide substrate.
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: pol1. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B (298 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
5a9f
Crystal structure of the helicase domain of human DNA polymerase theta in complex with adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chain: A (780 residues)
5a9j
Crystal structure of the helicase domain of human DNA polymerase theta, apo-form
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chains: A, B, C, D (805 residues)
5aga
Crystal structure of the helicase domain of human DNA polymerase theta in complex with amppnp
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chain: A (785 residues)
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
5bk4
Cryo-em structure of mcm2-7 double hexamer on dsdna
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23. Gene: mcm4, cdc54, hcd21, ypr019w, yp9531.13. Gene: mcm5, cdc46, ylr274w, l9328.1.
Chains: 2, 3, 4, 5, 6, 7, A, B, C, D, E, F (603 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5bnv
Crystal structure of human mcm2 hbd chaperoning a histone h3-h4 tetramer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3f3a, h3.3a, h3f3, pp781, h3f3b, h3.3b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: hist1h4a, h4/a, h4fa, hist1h4b, h4/i, h4fi, hist1h4c, h4/g, h4fg, hist1h4d, h4/b, h4fb, hist1h4e, h4/j, h4fj, hist1h4f, h4/c, h4fc, hist1h4h, h4/h, h4fh, hist1h4i, h4/m, h4fm, hist1h4j, h4/e,
Chains: F, C (58 residues)
5bnx
Crystal structure of human mcm2 hbd and asf1b chaperoning a histone h3.3-h4 dimer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3f3a, h3.3a, h3f3, pp781, h3f3b, h3.3b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hist1h4a, h4/a, h4fa, hist1h4b, h4/i, h4fi, hist1h4c, h4/g, h4fg, hist1h4d, h4/b, h4fb, hist1h4e, h4/j, h4fj, hist1h4f, h4/c, h4fc, hist1h4h, h4/h, h4fh, hist1h4i, h4/m, h4fm, hist1h4j, h4/e,
Chain: C (57 residues)
5bo0
Crystal structure of human mcm2 hbd and asf1b chaperoning a histone h3.2-h4 dimer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hist2h3a, hist2h3c, h3f2, h3fm, hist2h3d. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hist1h4a, h4/a, h4fa, hist1h4b, h4/i, h4fi, hist1h4c, h4/g, h4fg, hist1h4d, h4/b, h4fb, hist1h4e, h4/j, h4fj, hist1h4f, h4/c, h4fc, hist1h4h, h4/h, h4fh, hist1h4i, h4/m, h4fm, hist1h4j, h4/e,
Chain: C (57 residues)
5bz0
Crystal structure of ibv papain-like protease plpro c101s mutant in complex with ubiquitin
Source: Avian infectious bronchitis virus (strain beaudette). Ibv. Organism_taxid: 11122. Strain: beaudette. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus.
Chain: A (248 residues)
5c3i
Crystal structure of the quaternary complex of histone h3-h4 heterodimer with chaperone asf1 and the replicative helicase subunit mcm2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: asf1a, cgi-98, hspc146. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: hist1h3a, h3fa, hist1h3b, h3fl, hist1h3c, h3fc, hist1h3d, h3fb, hist1h3e, h3fd, hist1h3f, h3fi, hist1h3g, h3fh, hist1h3h, h3fk, hist1h3i, h3ff, hist1h3j, h3fj.
Chains: D, H, L, P, T, X (63 residues)
5c94
Infectious bronchitis virus nsp9
Source: Avian infectious bronchitis virus. Ibv. Organism_taxid: 11127. Strain: m41. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (116 residues) CATH domain: 2.40.10.250
5da1
A dimerization-dependent mechanism drives prrsv nsp11 functions as a beta interferon antagonist and endoribonuclease
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (222 residues)
5dcx
Structural studies of aav2 rep68 reveal a partially structured linker and compact domain conformation
Source: Adeno-associated virus 2. Aav-2. Organism_taxid: 10804. Gene: rep68. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K (209 residues) CATH domain: 3.40.1310.20
5ean
Crystal structure of dna2 in complex with a 5' overhang DNA
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: dna2, dna2l, kiaa0083. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 10090
Chain: A (1051 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5eaw
Crystal structure of dna2 nuclease-helicase
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: dna2, dna2l, kiaa0083. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chains: A, B (1046 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5eax
Crystal structure of dna2 in complex with an ssdna
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: dna2, dna2l, kiaa0083. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B (1046 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5eay
Crystal structure of a dna2 peptide in complex with rpa 70n
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rpa1, repa1, rpa70. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
Chains: E, F, G, H (12 residues)
5eu8
Structure of fipv main protease in complex with dual inhibitors
Source: Feline infectious peritonitis virus. Fipv. Organism_taxid: 11135. Gene: 1b, orf1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chain: A (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
5eyi
Structure of prrsv apo-nsp11 at 2.16a
Source: Prrsv 16244b. Porcine reproductive and respiratory syndrome virus 16244b. Organism_taxid: 300561. Strain: 16244b. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (223 residues)
5f17
Structure of eav nsp11 k170a mutant at 3.19a
Source: Equine arteritis virus bucyrus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (219 residues)
5f4h
Archael ruvb-like holiday junction helicase
Source: Sulfolobus islandicus (strain l.S.2.15 / lassen #1). Organism_taxid: 429572. Strain: l.S.2.15 / lassen #1. Gene: ls215_1665. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (437 residues)
5fm6
Double-heterohexameric rings of full-length rvb1(adp)rvb2(apo)
Source: Chaetomium thermophilum. Organism_taxid: 209285. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold. Expression_system_variant: gold
Chains: A, B (426 residues)
Bound ligands:   Het Group ADP corresponds to enzyme product ADP
  Het Group PO4 corresponds to enzyme product phosphate
5fm7
Double-heterohexameric rings of full-length rvb1(adp)rvb2(adp)
Source: Chaetomium thermophilum. Organism_taxid: 209285. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold. Expression_system_variant: gold
Chains: A, B (418 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5fmf
The p-lobe of RNA polymerase ii pre-initiation complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
Chain: V (174 residues)
5fw5
Crystal structure of human g3bp1 in complex with semliki forest virus nsp3-25 comprising two fgdf motives
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Semliki forest virus. Organism_taxid: 11033.
Chains: A, B (140 residues) CATH domain: 3.10.450.50
5fyw
Transcription initiation complex structures elucidate DNA opening (oc)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: bj5464 rpb3 his-bio. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril. Synthetic: yes. Synthetic construct.
Chain: R (199 residues)
5fz5
Transcription initiation complex structures elucidate DNA opening (cc)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: bj5464 rpb3 his-bio. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic. Organism_taxid: 32630.
Chain: R (199 residues)
5gn1
Crystal structure of thE C-terminal part of fun30 atpase domain
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: s288c. Atcc: 204508. Gene: fun30. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (309 residues)
5grq
Crystal structure of dhb domain of daxx in complex with an atrx peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: daxx, bing2, dap6. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: atrx, rad54l, xh2.
Chains: C, D (30 residues)
5hbz
Structure of eav nsp11 k170a mutant at 3.10a
Source: Equine arteritis virus bucyrus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (219 residues)
5hc1
Structure of eav nsp11 h141a mutant at 3.10a
Source: Equine arteritis virus bucyrus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (219 residues)
5hiy
Crystal structure of pedv nsp9 mutant-c59a
Source: Porcine epidemic diarrhea virus cv777. Pedv. Organism_taxid: 229032. Strain: cv777. Gene: rep, 1a-1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
Chains: A, B, C (95 residues) CATH domain: 2.40.10.250
5hiz
The structure of pedv nsp9
Source: Porcine epidemic diarrhea virus cv777. Pedv. Organism_taxid: 229032. Strain: cv777. Gene: rep, 1a-1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.
Chains: A, B (96 residues) CATH domain: 2.40.10.250
5hog
Crystal structure of the carboxy-terminal domain of yeast ctf4 bound to dna2.
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ctf4, chl15, pob1, ypr135w, p9659.7. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 4932
Chains: D, E (13 residues)
5hol
The crystal structure of the mers-cov macro domain with adp-ribose
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: tuner placi.
Chain: A (167 residues) CATH domain: 3.40.220.10
Bound ligand:   Het Group APR is 75.00% similar to enzyme product ADP
5i9e
Crystal structure of a nuclear actin ternary complex
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: arp4, act3, yjl081c, j1012. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Saccharomyces bayanus.
Chains: H, E (44 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
5ikn
Crystal structure of the t7 replisome in the absence of DNA
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Escherichia coli o157:h7. Organism_taxid: 83334. Gene: trxa, z5291, ecs4714. Expression_system_taxid: 562
Chains: D, E, F, G, H, I, J (485 residues)
5iy0
Pfmcm n-terminal domain double hexamer
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: pf0482. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (253 residues) CATH domains: 3.30.1640.10 2.40.50.140 2.20.28.10
5iy6
Human holo-pic in the closed state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid.
Chain: T (222 residues)
5iy7
Human holo-pic in the open state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid.
Chain: T (222 residues)
5iy8
Human holo-pic in the initial transcribing state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polr2i. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2b, tf2b, tfiib. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2.
Chain: T (222 residues)
5iy9
Human holo-pic in the initial transcribing state (no iis)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid.
Chain: T (222 residues)
5iya
Human core-pic in the closed state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid.
Chain: T (222 residues)
5iyb
Human core-pic in the open state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid.
Chain: T (222 residues)
5iyc
Human core-pic in the initial transcribing state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid.
Chain: T (222 residues)
5iyd
Human core-pic in the initial transcribing state (no iis)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a1, tf2a1. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid.
Chain: T (222 residues)
5ja4
Crystal structure of human tonsl and mcm2 hbds binding to a histone h3-h4 tetramer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3f3a, h3.3a, h3f3, pp781, h3f3b, h3.3b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: hist1h4a, h4/a, h4fa, hist1h4b, h4/i, h4fi, hist1h4c, h4/g, h4fg, hist1h4d, h4/b, h4fb, hist1h4e, h4/j, h4fj, hist1h4f, h4/c, h4fc, hist1h4h, h4/h, h4fh, hist1h4i, h4/m, h4fm, hist1h4j, h4/e,
Chain: C (57 residues)
5jno
Crystal structure of the bd1-ntpr complex from bend3 and pich
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bend3, kiaa1553. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta. Gene: ercc6l, pich.
Chain: B (57 residues)
5ko3
Structure of a core papain-like protease of mers coronavirus with utility for structure-based drug design
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domains: 1.10.8.1190 2.60.120.1680
5lac
Semet labeled derivative of cavally virus 3cl protease
Source: Cavally virus. Cavv. Organism_taxid: 1041929. Gene: pp1ab, cavv_gp1. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: methionine auxotroph.
Chains: A, B (298 residues)
5lak
Ligand-bound structure of cavally virus 3cl protease
Source: Cavally virus. Organism_taxid: 1041929. Gene: pp1ab, cavv_gp1. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: tb1. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B, C, D (303 residues)
5nfy
Sars-cov nsp10/nsp14 dynamic complex
Source: Sars coronavirus frankfurt 1. Organism_taxid: 229992. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, M, N, O, P (512 residues)
5nh0
Structure of human coronavirus nl63 main protease in complex with the alpha-ketoamide tert-butyl ((s)-4-(benzylamino)-3,4-dioxo-1-((s)-2- oxopyrrolidin-3-yl)b- utan-2-yl)carbamate (tert-butyl -glnlactam-co- co-nh-benzyl)
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C (299 residues)
5oaf
Human rvb1/rvb2 heterohexamer in ino80 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46.
Chains: A, B, C, D, E, F (436 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5oqj
Structure of yeast transcription pre-initiation complex with tfiih
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Gene: sua7, ypr086w, p9513.4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct.
Chain: R (190 residues)
5oqm
Structure of yeast transcription pre-initiation complex with tfiih and core mediator
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: sua7, ypr086w, p9513.4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes.
Chain: R (190 residues)
5oun
Nmr solution structure of the external dii domain of rvb2 from saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: rvb2, tih2, tip49b, ypl235w, p1060. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (107 residues)
5sva
Mediator-RNA polymerase ii pre-initiation complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: sua7, ypr086w, p9513.4. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: toa1, yor194c. Gene: toa2, ykl058w. Gene: tfa1, ykl028w.
Chain: g (172 residues)
5u8s
Structure of eukaryotic cmg helicase at a replication fork
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: psf1, ydr013w, pza208, yd8119.18. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: psf2, yjl072c, hrf213, j1086.
Chains: 2, 3, 4, 5, 6, 7 (602 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
5u8t
Structure of eukaryotic cmg helicase at a replication fork and implications
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23.
Chains: 2, 3, 4, 5, 6, 7 (583 residues)
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
5utv
Sars-unique fold in the rousettus bat coronavirus hku9
Source: Rousettus bat coronavirus hku9. Btcov. Organism_taxid: 694006. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (77 residues)
5v69
Crystal structure of the middle east respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant me.4
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Organism_taxid: 9606. Expression_system_taxid: 469008
Chain: A (322 residues)
5v6a
Crystal structure of the middle east respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant me.2
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Organism_taxid: 9606. Expression_system_taxid: 469008
Chain: A (320 residues)
5v8f
Structural basis of mcm2-7 replicative helicase loading by orc-cdc6 and cdt1
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23.
Chains: 2, 3, 4, 5, 6, 7 (603 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
5vha
Dhx36 with an n-terminal truncation
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: dhx36. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (810 residues)
5vhc
Dhx36 with an n-terminal truncation bound to adp-bef3
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: dhx36. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: D (799 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5vhd
Dhx36 with an n-terminal truncation bound to adp-alf4
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: dhx36. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: D (795 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
5vhe
Dhx36 in complex with thE C-myc g-quadruplex
Source: Bos taurus. Bovine. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Organism_taxid: 9606
Chain: A (871 residues)
5vvr
Ternary complex of RNA pol ii, transcription scaffold and rad26
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Synthetic: yes. Saccharomyces cerevisiae. Organism_taxid: 4932. Organism_taxid: 4932
Chain: M (503 residues)
5w8t
Crystal structure of mers-cov papain-like protease in complex with thE C-terminal domain of human isg15
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: isg15, g1p2, ucrp. Expressed in: escherichia coli. Expression_system_taxid: 562. Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab.
Chains: A, C (319 residues)
5w8u
Crystal structure of mers-cov papain-like protease in complex with thE C-terminal domain of human isg15
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Gene: isg15, g1p2, ucrp.
Chains: A, C (319 residues)
5wfi
X-ray structure of mhv plp2 (cys1716ser) catalytic mutant in complex with free ubiquitin
Source: Murine coronavirus (strain a59). Mhv-a59. Organism_taxid: 11142. Strain: a59. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
Chains: A, B (301 residues)
5wwp
Crystal structure of middle east respiratory syndrome coronavirus helicase (mers-cov nsp13)
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: B, A (591 residues)
5xbc
Crystal structure basis for pedv nsp1
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (117 residues)
5xf8
Cryo-em structure of the cdt1-mcm2-7 complex in amppnp state
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23.
Chains: 2, 3, 4, 5, 6, 7 (591 residues)
5y18
Crystal structure of daxx helical bundle domain in complex with atrx
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: daxx, bing2, dap6. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: atrx, rad54l, xh2. Expression_system_taxid: 562
Chain: B (17 residues)
5y58
Crystal structure of ku70/80 and tlc1
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: yku70, hdf1, nes24, ymr284w, ym8021.10. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: yku80, hdf2, ymr106c, ym9718.05c.
Chains: A, B, C, D, E, F (548 residues)
5y59
Crystal structure of ku80 and sir4
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: yku80, hdf2, ymr106c, ym9718.05c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Saccharomyces cerevisiae.
Chain: B (188 residues)
5y6o
Crystal structure of daxx n-terminal four-helix bundle domain (4hb) in complex with atrx
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: daxx, bing2, dap6, atrx, rad54l, xh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I (105 residues)
5ym6
Crystal structure of porcine delta coronavirus nsp9
Source: Porcine coronavirus hku15. Organism_taxid: 1159905. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D (97 residues)
5ym8
Crystal structure of porcine delta coronavirus nsp9-n7
Source: Porcine coronavirus hku15. Organism_taxid: 1159905. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (90 residues)
5yn5
Crystal structure of mers-cov nsp10/nsp16 complex
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (289 residues)
5yn6
Crystal structure of mers-cov nsp10/nsp16 complex bound to sam
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (283 residues)
5yn8
Crystal structure of mers-cov nsp16/nsp10 complex bound to sah
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (281 residues)
5ynb
Crystal structure of mers-cov nsp16/nsp10 complex bound to sinefungin
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (291 residues)
5ynf
Crystal structure of mers-cov nsp16/nsp10 complex bound to m7gpppa
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (293 residues)
5yni
Crystal structure of mers-cov nsp16/nsp10 complex bound to sam and m7gpppg
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (294 residues)
5ynj
Crystal structure of mers-cov nsp16/nsp10 complex bound to m7gpppg
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (293 residues)
5ynm
Crystal structure of mers-cov nsp16/nsp10 complex bound to sam and m7gpppa
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (290 residues)
5ynn
Crystal structure of mers-cov nsp16/nsp10complex bound to sinefungin and m7gpppg
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (295 residues)
5yno
Crystal structure of mers-cov nsp16/nsp10 complex bound to sah and m7gpppa
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (291 residues)
5ynp
Crystal structure of mers-cov nsp16/nsp10 complex bound to sinefungin and m7gpppa
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (294 residues)
5ynq
Crystal structure of mers-cov nsp16/nsp10 complex bound to sah and m7gpppg
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (291 residues)
5yvd
Structural and biochemical characterization of endoribonuclease nsp15 encoded by middle east respiratory syndrome coronavirus
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (341 residues)
5yww
Archael ruvb-like holiday junction helicase
Source: Sulfolobus islandicus rey15a. Organism_taxid: 930945. Strain: rey15a. Gene: sire_1432. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (485 residues)
5zqg
Complex structure of pedv 3clpro mutant (c144a) with nemo-231 peptite substrate
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Sus scrofa. Organism_taxid: 9823
Chains: A, B (292 residues)
6a9w
Structure of the bifunctional DNA primase-polymerase from phage nrs-1
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (281 residues)
6bi8
X-ray structure of mers coronavirus papain-like protease in complex with human isg15
Source: Human betacoronavirus 2c emc/2012. Organism_taxid: 1235996. Gene: orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: isg15, g1p2, ucrp.
Chains: A, B (259 residues)
6ej5
A conserved structural element in the RNA helicase upf1 regulates its catalytic activity in an isoform-specific manner
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: upf1, kiaa0221, rent1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (599 residues)
6eyc
Re-refinement of the mcm2-7 double hexamer using isolde
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae s288c. Expression_system_taxid: 559292. Gene: mcm3, yel032w, sygp-orf23.
Chains: 2, 3, 4, 5, 6, 7 (603 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6f0l
S. Cerevisiae mcm double hexamer bound to duplex DNA
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23.
Chains: 2, 3, 4, 5, 6, 7, A, B, C, D, E, F (603 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6fhs
Cryoem structure of ino80core
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Cell_line: high five cells (bti-tn-5b1-4). Gene: ctht_0006820. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five cells (bti-tn-5b1-4).
Chains: A, B, C, D, E, F (449 residues)
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
6fml
Cryoem structure ino80core nucleosome complex
Source: Chaetomium thermophilum (strain dsm 1495 / cbs 144.50 / imi 039719). Organism_taxid: 759272. Gene: ctht_0006820. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: ctht_0006170. 144.50 / imi 039719), chaetomium thermophilum var. Thermophilum dsm 1495.
Chains: A, B, C, D, E, F (449 residues)
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
6fo1
Human r2tp subcomplex containing 1 ruvbl1-ruvbl2 hexamer bound to 1 rbd domain from rpap3.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Gene: rpap3. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (323 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6fv1
Structure of human coronavirus nl63 main protease in complex with the alpha-ketoamide (s)-n-((s)-4-(benzylamino)-3,4-dioxo-1-((s)-2- oxopyrrolidin-3-yl)butan-2-yl)-2-cinnamamido-4-methylpentanamide (cinnamoyl-leucine-glnlactam-co-co-nh-benzyl)
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C (300 residues)
6fv2
Structure of human coronavirus nl63 main protease in complex with the alpha-ketoamide (s)-n-benzyl-3-((s)-2-cinnamamido-3- phenylpropanamido)-2-oxo-4-((s)-2-oxopyrrolidin-3-yl)butanamide (cinnamoyl-phenylalanine-glnlactam-co-co-nh-benzyl)
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C (301 residues)
6g0o
Crystal structure of the first bromodomain of human brd4 in complex with an acetylated atrx peptide (k1030ac/k1033ac)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: brd4, hunk1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: r3. Synthetic: yes. Organism_taxid: 9606
Chain: B (11 residues)
6gej
Chromatin remodeller-nucleosome complex at 3.6 a resolution.
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Organism_taxid: 559292. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Baker's yeast. Gene: hht1, ybr010w, ybr0201, hht2, sin2, ynl031c, n2749. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: M, T, U, V, W, X, Y (688 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6gen
Chromatin remodeller-nucleosome complex at 4.5 a resolution.
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Organism_taxid: 559292. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Baker's yeast. Gene: hht1, ybr010w, ybr0201, hht2, sin2, ynl031c, n2749. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: M, T, U, V, W, X, Y (688 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6gyk
Structure of a yeast closed complex (core cc1)
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Gene: sua7, ypr086w, p9513.4. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Gene: spt15, btf1, tbp1, yer148w.
Chain: R (132 residues)
6gyl
Structure of a yeast closed complex with distorted DNA (core ccdist)
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Gene: sua7, ypr086w, p9513.4. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Gene: spt15, btf1, tbp1, yer148w.
Chain: R (190 residues)
6gym
Structure of a yeast closed complex with distorted DNA (ccdist)
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Gene: rad3, rem1, yer171w. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: tfb1, ydr311w, d9740.3. Gene: tfb2, ypl122c.
Chain: R (190 residues)
6h3a
Crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: smarcad1, kiaa1122. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: trim28, kap1, rnf96, tif1b. Expression_system_taxid: 562
Chains: D, B (53 residues)
6h7x
First x-ray structure of full-length human ruvb-like 2.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (371 residues)
6hts
Cryo-em structure of the human ino80 complex bound to nucleosome
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_variant: sf9. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Gene: ino80, ino80a, inoc1, kiaa1259.
Chains: A, B, C, D, E, F (434 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6hv9
S. Cerevisiae cmg-pol epsilon-DNA
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm4, cdc54, hcd21, ypr019w, yp9531.13. Gene: pacbioseq_locus4112, pacbioseq_locus4129, pacbioseq_locus4153, pacbioseq_locus4202, scnyr20_0004029000, scp684_0004028600.
Chains: 3, 4, 5, 6, 2, 7 (558 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
6igm
Cryo-em structure of human srcap complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: mammal environmental sample. Expression_system_taxid: 1092587. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Gene: actr6, cda12. Gene: srcap, kiaa0309.
Chains: A, B, C, D, E, F (405 residues)
6ivc
The full length of tgev nsp1
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, E, F (105 residues)
6jde
Crystal structure of a DNA repair protein
Source: Escherichia coli k-12. Organism_taxid: 83333. Strain: k-12. Gene: radd, yejh, yeji, yejj, b2184, jw2172. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333.
Chains: B, A (567 residues)
6jdr
Crystal structure of methylated prrsv nsp10 (helicase)
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (430 residues)
6jds
Crystal structure of truncated prrsv nsp10 (helicase)
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (259 residues)
6jdu
Crystal structure of prrsv nsp10 (helicase)
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (425 residues)
6jij
The crystal structure of main protease from mouse hepatitis virus a59 in complex with an inhibitor
Source: Murine coronavirus (strain a59). Mhv-a59. Organism_taxid: 11142. Strain: a59. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: B, C, A (297 residues)
6jon
Crystal structures of phage nrs-1 n300-dntps-mg2+ complex provide molecular mechanisms for substrate specificity
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (280 residues)
6jop
Crystal structures of phage nrs-1 n300-dntps-mg2+ complex provide molecular mechanisms for substrate specificity
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (280 residues)
6joq
Crystal structures of phage nrs-1 n300-dntps-mg2+ complex provide molecular mechanisms for substrate specificity
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (280 residues)
6k0r
Ruvbl1-ruvbl2 with truncated domain ii in complex with phosphorylated cordycepin
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H, I, J, K, L (316 residues)
Bound ligands:   Het Group 3AT is 96.77% similar to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
6k15
Rsc substrate-recruitment module
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Strain: s288c. Strain: s288c
Chain: J (235 residues)
6k9a
The complex of nrs-1 n terminal domain (1-305) with dgtp
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chain: A (279 residues)
Bound ligand:   Het Group DGT is 93.75% similar to enzyme reactant ATP
6k9b
Apo structure of nrs-1 n terminal domain n305
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chains: A, B (279 residues)
6k9c
The apo structure of nrs-1 c terminal region (305-718)
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chains: A, B (416 residues)
6k9e
The a form apo structure of nrs-1 c terminal region-ctr(305-718)
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chains: A, B, C, D, E, F (402 residues)
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
6kmb
Crystal structure of sth1 bromodomain
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: sth1, nps1, yil126w. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta
Chains: A, B, C, D (110 residues)
6kmj
Crystal structure of sth1 bromodomain in complex with h3k14ac
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: sth1, nps1, yil126w. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chain: A (112 residues)
6kw3
The classa rsc-nucleosome complex
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hist1h2aj, loc494591, xelaev_18003602mg. Synthetic: yes. Homo sapiens. Organism_taxid: 9606.
Chains: W, J, Y (69 residues)
6kw4
The classb rsc-nucleosome complex
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hist1h2aj, loc494591, xelaev_18003602mg. Synthetic: yes. Homo sapiens. Organism_taxid: 9606.
Chains: J, V, Y (235 residues)
6kw5
The classc rsc-nucleosome complex
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli.
Chains: J, P, Q (235 residues)
6l0o
Wh domain of human mcm8
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm8, c20orf154. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chain: A (71 residues)
6l5t
The crystal structure of sads-cov papain like protease
Source: Swine acute diarrhea syndrome coronavirus. Organism_taxid: 2032731. Gene: orf1ab, orf1ab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (234 residues)
6l70
Complex structure of pedv 3clpro with gc376
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: pol1. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333.
Chains: A, B (299 residues)
6lkx
The structure of prrsv helicase
Source: Porcine reproductive and respiratory syndrome virus. Prrsv. Organism_taxid: 28344. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (441 residues)
6ln0
Crystal structure of three main domains of nonstructural protein 3 from coronavirus
Source: Porcine deltacoronavirus. Organism_taxid: 1586324. Gene: orf1ab. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chain: A (425 residues)
6lp9
The protein of cat virus
Source: Feline infectious peritonitis virus. Organism_taxid: 11135. Gene: 1b, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: B, A, C, D (104 residues)
6lpa
The nsp1 protein of a new porcine coronavirus
Source: Swine acute diarrhea syndrome coronavirus. Organism_taxid: 2032731. Gene: orf1ab, orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (101 residues)
6lqz
Solution structure of taf14et-sth1ebmc
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: taf14, anc1, cst10, swp29, taf30, tfg3, ypl129w. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sth1, nps1, yil126w.
Chain: B (58 residues)
6lrb
The a form apo structure of nrs-1 c terminal region-ctr
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (410 residues)
6mea
Crystal structure of a tylonycteris bat coronavirus hku4 macrodomain in complex with adenosine diphosphate ribose (adp-ribose)
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_cell_line: bl21(de3)plyss.
Chains: A, B (162 residues)
6meb
Crystal structure of tylonycteris bat coronavirus hku4 macrodomain in complex with nicotinamide adenine dinucleotide (NAD+)
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_cell_line: bl21(de3)plyss.
Chains: A, B (162 residues)
6men
Crystal structure of a tylonycteris bat coronavirus hku4 macrodomain in complex with adenosine diphosphate glucose (adp-glucose)
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_cell_line: bl21(de3)plyss.
Chains: A, B (162 residues)
6mii
Crystal structure of minichromosome maintenance protein mcm/DNA complex
Source: Sulfolobus solfataricus (strain atcc 35092 / dsm 1617 / jcm 11322 / p2). Organism_taxid: 273057. Strain: atcc 35092 / dsm 1617 / jcm 11322 / p2. Gene: mcm, sso0774. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct.
Chains: A, B, C, D, E, F (585 residues)
Bound ligand:   Het Group 08T is 87.10% similar to enzyme product ADP
6mr4
Crystal structure of the sth1 bromodomain from s.Cerevisiae
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: sth1, nps1, yil126w. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (109 residues)
6mwm
Bat coronavirus hku4 sud-c
Source: Bat coronavirus hku4. Btcov. Organism_taxid: 694007. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (81 residues)
6n7i
Structure of bacteriophage t7 e343q mutant gp4 helicase-primase in complex with ssdna, dttp, ac dinucleotide and ctp (gp4(5)-DNA)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Variant: e343q. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (271 residues)
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
6n7n
Structure of bacteriophage t7 e343q mutant gp4 helicase-primase in complex with ssdna, dttp, ac dinucleotide and ctp (form i)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (271 residues)
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
6n7s
Structure of bacteriophage t7 e343q mutant gp4 helicase-primase in complex with ssdna, dttp, ac dinucleotide and ctp (form ii)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (271 residues)
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
6n7t
Structure of bacteriophage t7 e343q mutant gp4 helicase-primase in complex with ssdna, dttp, ac dinucleotide and ctp (form iii)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (271 residues)
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
6n7v
Structure of bacteriophage t7 gp4 (helicase-primase, e343q mutant) in complex with ssdna, dttp, ac dinucleotide, and ctp (from multiple lead complexes)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (271 residues)
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
6n9u
Structure of bacteriophage t7 lagging-strand DNA polymerase (d5a/e7a) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dttp (from lags1)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Bacteriophage t7. Synthetic: yes. Organism_taxid: 10760
Chains: E, F (222 residues)
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
6n9v
Structure of bacteriophage t7 lagging-strand DNA polymerase (d5a/e7a) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dttp (lags1)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Bacteriophage t7. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (253 residues)
Bound ligand:   Het Group TTP is 76.47% similar to enzyme reactant ATP
6n9w
Structure of bacteriophage t7 lagging-strand DNA polymerase (d5a/e7a) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dttp (lags2)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Bacteriophage t7. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (496 residues)
6n9x
Structure of bacteriophage t7 lagging-strand DNA polymerase (d5a/e7a) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dttp (lags3)
Source: Enterobacteria phage t7. Organism_taxid: 10760. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10760
Chains: A, B, C, D, E, F (271 residues)
6noz
X-ray structure of pedv papain-like protease 2
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chain: A (248 residues)
6o9l
Human holo-pic in the closed state
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gtf2a2, tf2a2. Gene: tbp, gtf2d1, tf2d, tfiid. Gene: gtf2e1, tf2e1.
Chain: T (237 residues)
6ptj
Structure of ctf4 trimer in complex with one cmg helicase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: psf1, ydr013w, pza208, yd8119.18. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Saccharomyces cerevisiae (strain atcc 204508 / s288c). Organism_taxid: 559292.
Chains: 2, 3, 4, 5, 6, 7 (260 residues)
6ptn
Structure of ctf4 trimer in complex with two cmg helicases
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ctf4, chl15, pob1, ypr135w, p9659.7. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: psf1, ydr013w, pza208, yd8119.18. Gene: psf2, yjl072c, hrf213, j1086. Gene: psf3, yol146w.
Chains: i, j, k, l, m, n, 2, 3, 4, 5, 6, 7 (634 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
6q6r
Recognition of different base tetrads by rhau: x-ray crystal structure of g4 recognition motif bound to the 3-end tetrad of a DNA g- quadruplex
Source: Unidentified. Organism_taxid: 32644. Expressed in: synthetic construct. Expression_system_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: dhx36, ddx36, kiaa1488, mlel1, rhau. Expressed in: escherichia coli.
Chains: E, F, G, H (17 residues)
6qi8
Truncated human r2tp complex, structure 3 (adp-filled)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Expression_system_taxid: 511693
Chains: A, B, C, D, E, F (317 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6qi9
Truncated human r2tp complex, structure 4 (adp-empty)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Expression_system_taxid: 469008
Chains: A, B, C, D, E, F (317 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
6qu1
Crystal structure of the kap1 rbcc domain in complex with the smarcad1 cue1 domain at 3.7 angstrom resolution.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim28, kap1, rnf96, tif1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: smarcad1, kiaa1122. Expression_system_taxid: 562
Chain: D (48 residues)
6raw
D. Melanogaster cmg-DNA, state 1a
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: mcm2, cg7538. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: mcm3, mcm3-ra, cg4206. Gene: dpa, cg1616. Gene: mcm5, cg4082.
Chains: 2, 3, 4, 5, 6, 7 (603 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
6rax
D. Melanogaster cmg-DNA, state 1b
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: mcm2, cg7538. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: mcm3, mcm3-ra, cg4206. Gene: dpa, cg1616. Gene: mcm5, cg4082.
Chains: 2, 3, 4, 5, 6, 7 (605 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
6ray
D. Melanogaster cmg-DNA, state 2a
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: mcm3, mcm3-ra, cg4206. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: dpa, cg1616. Gene: mcm7, cg4978. Gene: mcm6, cg4039.
Chains: 3, 4, 7, 6, 5, 2 (600 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
6raz
D. Melanogaster cmg-DNA, state 2b
Source: Synthetic: yes. Drosophila melanogaster. Organism_taxid: 7227. Fruit fly. Gene: cdc45l, anon-1ec, cdc45, cdc45, cdc45, d, dcdc45, dcdc45l, dmcdc45, dmel\cg3658, eg:bacr7a4.11, cg3658, dmel_cg3658. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: psf1, cg9187-pa, dmel\cg9187, psf1, cg9187, dmel_cg9187.
Chains: 2, 5, 6, 3, 4, 7 (559 residues)
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
6rpp
Crystal structure of pabcdc21-1 intein
Source: Pyrococcus abyssi (strain ge5 / orsay). Organism_taxid: 272844. Gene: cdc21, pab2373. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: t7 express.
Chain: A (168 residues)
6rpq
Crystal structure of phocdc21-1 intein
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c), pyrococcus horikoshii (strain atcc 700860 / dsm 12428 / jcm 9974 / nbrc 100139 / ot-3). Baker's yeast. Organism_taxid: 559292, 70601. Strain: atcc 204508 / s288c, atcc 700860 / dsm 12428 / jcm 9974 / nbrc 100139 / ot-3. Gene: smt3, ydr510w, d9719.15, ph0606. Expressed in: escherichia coli.
Chain: A (249 residues)
6sko
Cryo-em structure of the fork protection complex bound to cmg at a replication fork - conformation 2 mcm ctd:ssdna
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Organism_taxid: 559292. Gene: mcm6, ygl201c. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm7, cdc47, ybr202w, ybr1441. Gene: mcm2, ybl023c, ybl0438. Gene: mcm5, cdc46, ylr274w, l9328.1.
Chains: 6, 7, 2, 5, 3, 4 (328 residues)
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
6ta7
Crystal structure of human g3bp1-ntf2 in complex with human caprin1- derived solomon motif
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
Chains: A, B, D, F, C, E (131 residues)
6tda
Structure of swi/snf chromatin remodeler rsc bound to a nucleosome
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hist1h2aj, loc494591. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chain: S (783 residues)
6u0m
Structure of the s. Cerevisiae replicative helicase cmg in complex with a forked DNA
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: psf1, ydr013w, pza208, yd8119.18. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: psf2, yjl072c, hrf213, j1086. Gene: psf3, yol146w. Gene: sld5, ydr489w.
Chains: 2, 3, 4, 5, 6, 7 (634 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
6usm
Structure of nuclease domain of human parvovirus b19 non-structural protein 1 in complex with zinc
Source: Escherichia coli. Organism_taxid: 562. Gene: male. Expressed in: expression vector pet-mod. Expression_system_taxid: 1685505. Human parvovirus b19. Hpv b19. Organism_taxid: 10798. Gene: ns.
Chain: B (164 residues)
6uy1
Crystal structure of the sth1 bromodomain from saccharomyces cerevisiae at 2.2 angstrom resolution
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: sth1, nps1, yil126w. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (110 residues)
6v8o
Rsc core
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
Chain: R (262 residues)
6v92
Rsc-ncp
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens.
Chain: R (325 residues)
6vgy
2.05 a resolution structure of mers 3cl protease in complex with inhibitor 6b
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (297 residues)
6vgz
2.25 a resolution structure of mers 3cl protease in complex with inhibitor 6d
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (296 residues)
6vh0
1.95 a resolution structure of mers 3cl protease in complex with inhibitor 6g
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (297 residues)
6vh1
2.30 a resolution structure of mers 3cl protease in complex with inhibitor 6h
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (298 residues)
6vh2
2.26 a resolution structure of mers 3cl protease in complex with inhibitor 7i
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (299 residues)
6vh3
2.20 a resolution structure of mers 3cl protease in complex with inhibitor 7j
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (300 residues)
6vsx
X-ray crystal structure of thE C-terminal domain of bacillus subtilis RNA polymerase binding helicase held
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: b4417_3167. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (159 residues)
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
6vz4
Cryo-em structure of sth1-arp7-arp9-rtt102 bound to the nucleosome in adp beryllium fluoride state
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Gene: hist1h3g, h3c8, h3l. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: hist1h2aj, loc494591, xelaev_18003602mg. Gene: h2b, xelaev_18028547mg. Synthetic construct.
Chain: K (616 residues)
6vzg
Cryo-em structure of sth1-arp7-arp9-rtt102
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: arp7, swp61, ypr034w, yp9367.14. Expressed in: escherichia coli. Expression_system_taxid: 562. Saccharomyces cerevisiae.
Chain: K (62 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
6wgc
Atomic model of semi-attached mutant occm-DNA complex (orc-cdc6-cdt1- mcm2-7 with mcm6 whd truncation)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: cdc6, yjl194w, j0347. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: orc1, yml065w. Gene: orc2, rrr1, sir5, ybr060c, ybr0523. Gene: orc3, oaf1, oif1, yll004w, l1365.
Chains: 3, 7 (69 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
6wgf
Atomic model of mutant mcm2-7 hexamer with mcm6 whd truncation
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm7, cdc47, ybr202w, ybr1441. Gene: mcm6, ygl201c. Gene: mcm5, cdc46, ylr274w, l9328.1.
Chains: 2, 7, 6, 5, 4, 3 (508 residues)
6wgg
Atomic model of pre-insertion mutant occm-DNA complex(orc-cdc6-cdt1- mcm2-7 with mcm6 whd truncation)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: tah11, cdt1, sid2, yjr046w, j1641. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: cdc6, yjl194w, j0347. Gene: orc1, yml065w. Gene: orc2, rrr1, sir5, ybr060c, ybr0523.
Chains: 2, 3, 4, 5, 6, 7 (581 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
6wgi
Atomic model of the mutant occm (orc-cdc6-cdt1-mcm2-7 with mcm6 whd truncation) loaded on DNA at 10.5 a resolution
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: cdc6, yjl194w, j0347. Gene: orc1, yml065w. Gene: orc2, rrr1, sir5, ybr060c, ybr0523. Gene: orc3, oaf1, oif1, yll004w, l1365.
Chains: 2, 3, 4, 5, 6, 7 (573 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
6wnz
Structure of a dimer of the sulfolobus solfataricus mcm n-terminal domain reveals potential role in mcm ring opening
Source: Saccharolobus solfataricus (strain atcc 35092 / dsm 1617 / jcm 11322 / p2). Organism_taxid: 273057. Strain: atcc 35092 / dsm 1617 / jcm 11322 / p2. Gene: mcm, sso0774. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: B, A (261 residues)
6wvk
Cryo-em structure of bacillus subtilis RNA polymerase in complex with held
Source: Bacillus subtilis (strain 168). Organism_taxid: 224308. Strain: 168. Strain: 168
Chain: H (770 residues)
6xb8
Adeno-associated virus origin binding domain in complex with ssdna
Source: Adeno-associated virus 2 (isolate srivastava/1982). Aav-2. Organism_taxid: 648242. Strain: isolate srivastava/1982. Gene: rep68. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss.
Chains: A, B, C, D (205 residues)
6xbu
Polymerase domain of polymerase-theta
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chain: A (605 residues)
6xtx
Cryoem structure of human cmg bound to atpgammas and DNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm2, bm28, ccnl1, cdcl1, kiaa0030. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293f. Gene: mcm3. Gene: mcm4, cdc21.
Chains: 2, 3, 4, 5, 6, 7 (691 residues)
Bound ligands:   Het Group AGS is 93.75% similar to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
6xty
Cryoem structure of human cmg bound to and-1 (cmga)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm2, bm28, ccnl1, cdcl1, kiaa0030. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293f. Gene: mcm3. Gene: mcm4, cdc21.
Chains: 2, 3, 4, 5, 6, 7 (611 residues)
6yxu
Structure of mycobacterium smegmatis held protein in complex with RNA polymerase core - state i, primary channel engaged
Source: Mycolicibacterium smegmatis mc2 155. Organism_taxid: 246196. Gene: rpoa, msmeg_1524, msmei_1488. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rpob, msmeg_1367, msmei_1328. Gene: rpoc, msmeg_1368, msmei_1329. Gene: rpoz, msmeg_3053, msmei_2977. Gene: msmeg_2174.
Chain: H (691 residues)
6yys
Structure of mycobacterium smegmatis held protein in complex with RNA polymerase core - state ii, primary channel engaged and active site interfering
Source: Mycolicibacterium smegmatis mc2 155. Organism_taxid: 246196. Gene: rpoa, msmeg_1524, msmei_1488. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rpob, msmeg_1367, msmei_1328. Gene: rpoc, msmeg_1368, msmei_1329. Gene: rpoz, msmeg_3053, msmei_2977. Gene: msmeg_2174.
Chain: H (690 residues)
6z11
Structure of mycobacterium smegmatis held protein in complex with RNA polymerase core - state iii, primary channel dis-engaged and active site interfering
Source: Mycolicibacterium smegmatis mc2 155. Organism_taxid: 246196. Gene: rpoa, msmeg_1524, msmei_1488. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rpob, msmeg_1367, msmei_1328. Gene: rpoc, msmeg_1368, msmei_1329. Gene: rpoz, msmeg_3053, msmei_2977. Gene: msmeg_2174.
Chain: H (193 residues)
6zca
Structure of the b. Subtilis RNA polymerase in complex with held (monomer)
Source: Bacillus subtilis. Organism_taxid: 1423. Organism_taxid: 1423
Chain: H (771 residues)
6zfb
Structure of the b. Subtilis RNA polymerase in complex with held (dimer)
Source: Bacillus subtilis. Organism_taxid: 1423. Organism_taxid: 1423
Chains: H, h (771 residues)
7aho
Ruvbl1-ruvbl2 heterohexameric ring after binding of RNA helicase dhx34
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (305 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
7ciz
Crystal structure of dnajc9 hbd helix2 in complex with h3.3-h4 dimer and mcm2 hbd
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3-3a, h3.3a, h3f3, h3f3a, pp781, h3-3b, h3.3b, h3f3b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Gene: hist1h4a, h4/a, h4fa, hist1h4b, h4/i, h4fi, hist1h4c, h4/g, h4fg, hist1h4d, h4/b, h4fb, hist1h4e, h4/j, h4fj, hist1h4f, h4/c, h4fc, hist1h4h, h4/h, h4fh, hist1h4i, h4/m, h4fm, hist1h4j, h4/e,
Chains: C, G, K (58 residues)
7cj0
Crystal structure of dnajc9 hbd in complex with h3.3-h4 dimer and mcm2 hbd
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: h3-3a, h3.3a, h3f3, h3f3a, pp781, h3-3b, h3.3b, h3f3b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: hist1h4a, h4/a, h4fa, hist1h4b, h4/i, h4fi, hist1h4c, h4/g, h4fg, hist1h4d, h4/b, h4fb, hist1h4e, h4/j, h4fj, hist1h4f, h4/c, h4fc, hist1h4h, h4/h, h4fh, hist1h4i, h4/m, h4fm, hist1h4j, h4/e,
Chains: G, H (60 residues)
7d3c
The newly emerged sars-like coronavirus hcov-emc also has an "achilles' heel": current effective inhibitor targeting a 3c-like protease
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: B, A (299 residues)
7dp3
Human mcm8 n-terminal domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm8, c20orf154. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (278 residues)
7dpd
Human mcm9 n-terminal domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm9, c6orf61, mcmdc1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (272 residues)
7dr8
Crystal structure of mers-cov 3cl protease in spacegroup p212121
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (295 residues)
7dr9
Crystal structure of mers-cov 3cl protease (c148a) in spacegroup p212121
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (279 residues)
7dra
Crystal structure of mers-cov 3cl protease (c148a) in spacegroup p212121,ph 9.0
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (279 residues)
7edx
P53-bound tfiid-based core pic on hdm2 promoter
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: taf1, ba2r, ccg1, ccgs, taf2a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: taf2, cif150, taf2b. Gene: taf4, taf2c, taf2c1, taf4a, tafii130, tafii135. Gene: taf5, taf2d.
Chain: T (113 residues)
7eg7
Tfiid-based core pic on scp promoter
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: taf1, ba2r, ccg1, ccgs, taf2a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: taf2, cif150, taf2b. Gene: taf4, taf2c, taf2c1, taf4a, tafii130, tafii135. Gene: taf5, taf2d.
Chain: T (113 residues)
7eg8
Tfiid-based core pic on puma promoter
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: taf1, ba2r, ccg1, ccgs, taf2a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: taf2, cif150, taf2b. Gene: taf4, taf2c, taf2c1, taf4a, tafii130, tafii135. Gene: taf5, taf2d.
Chain: T (222 residues)
7eg9
Tfiid-based intermediate pic on scp promoter
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: taf1, ba2r, ccg1, ccgs, taf2a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: taf2, cif150, taf2b. Gene: taf4, taf2c, taf2c1, taf4a, tafii130, tafii135. Gene: taf5, taf2d.
Chain: T (103 residues)
7ega
Tfiid-based intermediate pic on puma promoter
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: taf1, ba2r, ccg1, ccgs, taf2a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: taf2, cif150, taf2b. Gene: taf4, taf2c, taf2c1, taf4a, tafii130, tafii135. Gene: taf5, taf2d.
Chain: T (222 residues)
7ene
Crystal structure of mers-cov 3clpro in complex with the non-covalent inhibitor wu-04
Source: Middle east respiratory syndrome coronavirus. Organism_taxid: 1335626. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (304 residues)
7f0u
Porcine epidemic diarrhea virus papain-like protease 2 c44s mutant in complex with mono ubiquitin
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913
Chains: A, B (217 residues)
7f3s
Crystal structure of sth1 bromodomain in complex with h3k14bz peptide
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: sth1, nps1, yil126w. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes.
Chain: A (110 residues)
7f52
Crystal structure of ibv nsp2
Source: Infectious bronchitis virus. Organism_taxid: 11120. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (584 residues)
7jse
Adeno-associated virus origin binding domain in complex with ssdna
Source: Adeno-associated virus - 2. Aav-2. Organism_taxid: 10804. Gene: rep68. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P (198 residues)
7jsf
Adeno-associated virus helicase domain heptamer with ssdna
Source: Adeno-associated virus - 2. Aav-2. Organism_taxid: 10804. Gene: rep68. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B, C, D, E, F, G (276 residues)
7jsg
Adeno-associated virus 2 rep68 hd-heptamer-ssdna with atpgs
Source: Adeno-associated virus - 2. Aav-2. Organism_taxid: 10804. Gene: rep68. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B, C, D, E, F, G (272 residues)
7jsh
Adeno-associated virus 2 rep68 hd heptamer-ssaavs1 with atpgs
Source: Adeno-associated virus - 2. Aav-2. Organism_taxid: 10804. Gene: rep68. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B, C, D, E, F, G (272 residues)
7jsi
Adeno-associated virus 2 rep68 hd hexamer-ssdna with atpgs
Source: Adeno-associated virus - 2. Aav-2. Organism_taxid: 10804. Gene: rep68. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B, C, D, E, F (276 residues)
7nh7
Oc43 coronavirus methyltransferase
Source: Human coronavirus oc43. Hcov-oc43. Organism_taxid: 31631. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: 1a. Expression_system_taxid: 469008
Chain: A (295 residues)
Bound ligand:   Het Group SFG is 50.00% similar to enzyme product ADP
7nvr
Human mediator with RNA polymerase ii pre-initiation complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ercc2, xpd, xpdc. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gtf2h1, btf2. Gene: gtf2h4. Gene: mnat1, cap35, mat1, rnf66.
Chain: R (222 residues)
7nvs
RNA polymerase ii core pre-initiation complex with closed promoter DNA in proximal position
Source: Sus scrofa. Pig. Organism_taxid: 9823. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: R (222 residues)
7nvt
RNA polymerase ii core pre-initiation complex with closed promoter DNA in distal position
Source: Sus scrofa. Pig. Organism_taxid: 9823. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: R (222 residues)
7nvu
RNA polymerase ii core pre-initiation complex with open promoter DNA
Source: Sus scrofa. Pig. Organism_taxid: 9823. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: R (222 residues)
7nvy
RNA polymerase ii pre-initiation complex with closed promoter DNA in proximal position
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ercc2, xpd, xpdc. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gtf2h1, btf2. Gene: gtf2h4. Gene: mnat1, cap35, mat1, rnf66.
Chain: R (222 residues)
7nvz
RNA polymerase ii pre-initiation complex with closed promoter DNA in distal position
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ercc2, xpd, xpdc. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gtf2h1, btf2. Gene: gtf2h4. Gene: mnat1, cap35, mat1, rnf66.
Chain: R (222 residues)
7nw0
RNA polymerase ii pre-initiation complex with open promoter DNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ercc2, xpd, xpdc. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: gtf2h1, btf2. Gene: gtf2h4. Gene: mnat1, cap35, mat1, rnf66.
Chain: R (222 residues)
7o4i
Yeast RNA polymerase ii transcription pre-initiation complex with initial transcription bubble
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rad3, rem1, yer171w. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: tfb1, ydr311w, d9740.3.
Chain: R (268 residues)
7o4j
Yeast RNA polymerase ii transcription pre-initiation complex (consensus)
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rad3, rem1, yer171w. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: tfb1, ydr311w, d9740.3.
Chain: R (268 residues)
7o72
Yeast RNA polymerase ii transcription pre-initiation complex with closed promoter DNA
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expressed in: saccharomyces cerevisiae s288c. Expression_system_taxid: 559292. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes.
Chain: R (261 residues)
7o73
Yeast RNA polymerase ii transcription pre-initiation complex with closed distorted promoter DNA
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: rad3, rem1, yer171w. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: tfb1, ydr311w, d9740.3.
Chain: R (268 residues)
7o75
Yeast RNA polymerase ii transcription pre-initiation complex with open promoter DNA
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expressed in: saccharomyces cerevisiae s288c. Expression_system_taxid: 559292. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Baker's yeast.
Chain: R (268 residues)
7oa5
Ruva complexed to a holliday junction.
Source: Mycobacterium leprae (strain tn). Organism_taxid: 272631. Strain: tn. Gene: ruva, ml0482, b1177_c2_188. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Mycobacterium leprae. Organism_taxid: 1769.
Chains: A, B, C, D, E, F, G, H (181 residues)
7ole
Cryo-em structure of the telo2-tti1-tti2-ruvbl1-ruvbl2 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Gene: tti1, kiaa0406, smg10. Expressed in: spodoptera aff. Frugiperda 1 bold-2017.
Chains: A, B, C, D, E, F (433 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
7p6x
Cryo-em structure of the hexameric ruvbl1-ruvbl2 in complex with znhit2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (320 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
7pbl
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s1 [t2 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva, a3104_04360, a3s30_12815, a3t81_10475, a3u32_08040, a3v03_15555, a3v89_15755, a3w57_12595, a3w75_09730, a3x15_16725,
Chain: G (48 residues)
7pbm
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s2 [t2 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva, a3104_04360, a3s30_12815, a3t81_10475, a3u32_08040, a3v03_15555, a3v89_15755, a3w57_12595, a3w75_09730, a3x15_16725,
Chains: G, H (48 residues)
7pbn
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s3 [t2 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva, a3104_04360, a3s30_12815, a3t81_10475, a3u32_08040, a3v03_15555, a3v89_15755, a3w57_12595, a3w75_09730, a3x15_16725,
Chains: G, H (48 residues)
7pbo
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s4 [t2 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva, a3104_04360, a3s30_12815, a3t81_10475, a3u32_08040, a3v03_15555, a3v89_15755, a3w57_12595, a3w75_09730, a3x15_16725,
Chains: G, H (48 residues)
7pbp
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s5 [t2 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva. Expressed in: escherichia coli bl21(de3).
Chains: G, H (48 residues)
7pbq
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s0+a [t2 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva, a3104_04360, a3s30_12815, a3t81_10475, a3u32_08040, a3v03_15555, a3v89_15755, a3w57_12595, a3w75_09730, a3x15_16725,
Chain: G (48 residues)
7pbs
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s0+a [t1 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva, a3104_04360, a3s30_12815, a3t81_10475, a3u32_08040, a3v03_15555, a3v89_15755, a3w57_12595, a3w75_09730, a3x15_16725,
Chain: G (48 residues)
7pbt
Ruvab branch migration motor complexed to the holliday junction - ruvb aaa+ state s1 [t1 dataset]
Source: Streptococcus thermophilus. Organism_taxid: 1308. Gene: ruvb, cda68_01670, sthermo_2112. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Salmonella typhimurium. Organism_taxid: 90371. Gene: ruva, a3104_04360, a3s30_12815, a3t81_10475, a3u32_08040, a3v03_15555, a3v89_15755, a3w57_12595, a3w75_09730, a3x15_16725,
Chain: G (48 residues)
7pbu
Ruvab branch migration motor complexed to the holliday junction - ruva-hj core [t2 dataset]
Source: Salmonella typhimurium
Chains: A, B, C, D, F, H, J, L (133 residues)
7pmk
S. Cerevisiae replisome-scf(dia2) complex bound to double-stranded DNA (conformation i)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: pacbioseq_locus187, pacbioseq_locus193, pacbioseq_locus195, pacbioseq_locus196, scnyr20_0007007400, scp684_0007007100. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Saccharomyces cerevisiae (strain atcc 204508 / s288c).
Chains: 2, 3, 4, 5, 6, 7 (655 residues)
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
7r7j
Crystal structure of radd with adp
Source: Escherichia coli (strain k12). Organism_taxid: 83333. Strain: k12. Gene: radd, yejh, yeji, yejj, b2184, jw2172. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Expression_system_variant: stl2669(de3)
Chains: A, B (572 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
7rr3
Structure of deep-sea phage nrs-1 primase-polymerase n300 in complex with calcium and ddctp
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (275 residues)
7rr4
Structure of deep-sea phage nrs-1 primase-polymerase n300 in complex with magnesium and pyrophosphate
Source: Nitratiruptor phage nrs-1. Organism_taxid: 1230469. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (273 residues)
7s17
Crystal structure of human g3bp1-ntf2 with three mutations- f15w, f33w, and f124w
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (139 residues)
7smv
Crystallization of feline coronavirus mpro with gc376 reveals mechanism of inhibition
Source: Feline coronavirus. Organism_taxid: 12663. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (299 residues)
7sna
Crystallization of feline coronavirus mpro with gc376 reveals mechanism of inhibition
Source: Feline coronavirus. Organism_taxid: 12663. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (302 residues)
7suo
Crystal structure of the g3bp1 ntf2-like domain bound to the idr1 of sars-cov-2 nucleocapsid protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2.
Chains: A, B (136 residues)
7tq7
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 13c
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (302 residues)
7tq8
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 14d
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (302 residues)
7ux9
Arabidopsis ddm1 bound to nucleosome (h2a.W, h2b, h3.3, h4, with 147 bp DNA)
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: at5g59870, mmn10.22, mmn10_90. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss. Gene: at3g45980. Gene: htr4, at4g40030, t5j17.200, htr5, at4g40040, t5j17.210, htr8,
Chain: P (468 residues)
7vtc
Crystal structure of mers main protease in complex with pf07321332
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (299 residues)
7w68
Human single hexameric mcm2-7 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
Chains: A, B, C, D, E, F (560 residues)
7w7p
Cryo-em structure of gmcm8/9 helicase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: mcm9. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: mcm8, rcjmb04_5o15. Expression_system_taxid: 7111
Chains: A, B, C, D, E, F (272 residues)
7wfc
X-ray structure of hku1-plp2(cys109ser) catalytic mutant in complex with free ubiquitin
Source: Human coronavirus hku1. Organism_taxid: 290028. Gene: 1a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Gene: trees_t100014679.
Chain: A (309 residues)
7wi7
Crystal structure of human mcm8/9 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm8, c20orf154. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: mcm9, c6orf61, mcmdc1. Expression_system_taxid: 7111
Chains: A, B (565 residues)
7wku
Structure of pdcov mpro in complex with an inhibitor
Source: Porcine deltacoronavirus. Organism_taxid: 1586324. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: A, B, C, D, E, F (304 residues)
7wqh
Crystal structure of hcov-nl63 main protease with pf07304814
Source: Human coronavirus nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (299 residues)
7wqj
Crystal structure of mers main protease in complex with pf07304814
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (299 residues)
7x5a
Cryoem structure of ruva-holliday junction complex
Source: Pseudomonas aeruginosa pao1
Chains: E, F, G, H (137 residues)
7x7p
Cryoem structure of dsdna-ruvb-ruva domain3 complex
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Pseudomonas aeruginosa pao1. Organism_taxid: 208964. Strain: pao1. Gene: ruvb, pa0967. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: C, A, B, D (48 residues)
7xhf
Crystal structure of the ntf2l domain of human g3bp1 in complex with the usp10 derived peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B (124 residues)
7xhg
Crystal structure of the ntf2l domain of human g3bp1 in complex with the caprin-1 derived peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D (133 residues)
7xry
Crystal structure of mers main protease in complex with inhibitor yh- 53
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1ab. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (299 residues)
7xut
Crystal structure of rpa70n-wrn fusion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rpa1, repa1, rpa70, wrn, recq3, recql2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (136 residues)
7xuw
Crystal structure of rpa70n-blmp2 fusion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rpa1, repa1, rpa70, blm, recq2, recql3. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (137 residues)
7xv1
Crystal structure of rpa70n-helb fusion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rpa1, repa1, rpa70. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: helb. Expression_system_taxid: 562
Chain: B (29 residues)
7xwy
Crystal structure of spfft3 n-terminal truncation
Source: Schizosaccharomyces pombe 972h-. Organism_taxid: 284812. Strain: 972 / atcc 24843. Gene: fft3, snf2sr, spac25a8.01c. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (381 residues)
7xxe
Crystal structure of spfft3 c-terminal truncation
Source: Schizosaccharomyces pombe 972h-. Organism_taxid: 284812. Strain: 972 / atcc 24843. Gene: fft3, snf2sr, spac25a8.01c. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: B, A (275 residues)
7xyf
Cryo-em structure of fft3-nucleosome complex with fft3 bound to shl+2 position of the nucleosome
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: his2a, h2a, his2a:cg31618, cg31618, his2a:cg33808, cg33808, his2a:cg33814, cg33814, his2a:cg33817, cg33817, his2a:cg33820, cg33820, his2a:cg33823, cg33823, his2a:cg33826, cg33826, his2a:cg33829, cg33829, his2a:cg33832, cg33832, his2a:cg33835, cg33835, his2a:cg33838, cg33838, his2a:cg33841, cg33841, his2a:cg33844, cg33844, his2a:cg33847, cg33847, his2a:cg33850,
Chain: K (656 residues)
7xyg
Cryo-em structure of fft3-nucleosome complex with fft3 bound to shl+3 position of the nucleosome
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: his2a, h2a, his2a:cg31618, cg31618, his2a:cg33808, cg33808, his2a:cg33814, cg33814, his2a:cg33817, cg33817, his2a:cg33820, cg33820, his2a:cg33823, cg33823, his2a:cg33826, cg33826, his2a:cg33829, cg33829, his2a:cg33832, cg33832, his2a:cg33835, cg33835, his2a:cg33838, cg33838, his2a:cg33841, cg33841, his2a:cg33844, cg33844, his2a:cg33847, cg33847, his2a:cg33850,
Chain: K (650 residues)
7y56
Crystal structure of ns1 nuclease domain in p41212 space group
Source: Human parvovirus b19. Hpv b19. Organism_taxid: 10798. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (174 residues)
7y57
Crystal structure of ns1 nuclease domain in p21 space group
Source: Human parvovirus b19. Hpv b19. Organism_taxid: 10798. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (171 residues)
7yrz
Crystal structure of hcov 229e main protease in complex with pf07321332
Source: Human coronavirus 229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (298 residues)
7z05
White bream virus n7-methyltransferase
Source: White bream virus. Organism_taxid: 405554. Strain: isolate blicca bjoerkna l./Germany/df24/00. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chain: A (239 residues)
Bound ligand:   Het Group SAH is 51.43% similar to enzyme product ADP
7z2j
White bream virus n7-methyltransferase
Source: White bream virus. Organism_taxid: 405554. Strain: isolate blicca bjoerkna l./Germany/df24/00. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chain: A (225 residues)
Bound ligand:   Het Group SAH is 51.43% similar to enzyme product ADP
7z36
Crystal structure of the kap1 tripartite motif in complex with the znf93 krab domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trim28, kap1, rnf96, tif1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: znf93, znf505. Expression_system_taxid: 511693
Chains: C, S (46 residues)
7zm7
Cryoem structure of mitochondrial complex i from chaetomium thermophilum (inhibited by ddm)
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Strain: dsm 1495 / cbs 144.50 / imi 039719
Chain: S (72 residues)
Bound ligand:   Het Group NDP is 56.25% similar to enzyme product ADP
7zm8
Cryoem structure of mitochondrial complex i from chaetomium thermophilum (inhibited by ddm) - membrane arm
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Strain: dsm 1495 / cbs 144.50 / imi 039719
Chain: S (72 residues)
7zmb
Cryoem structure of mitochondrial complex i from chaetomium thermophilum (state 2)
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Strain: dsm 1495 / cbs 144.50 / imi 039719
Chain: S (74 residues)
Bound ligand:   Het Group NDP is 56.25% similar to enzyme product ADP
7zme
Cryoem structure of mitochondrial complex i from chaetomium thermophilum (state 2) - membrane arm
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Strain: dsm 1495 / cbs 144.50 / imi 039719
Chain: S (74 residues)
7zmg
Cryoem structure of mitochondrial complex i from chaetomium thermophilum (state 1)
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Strain: dsm 1495 / cbs 144.50 / imi 039719
Chain: S (74 residues)
7zmh
Cryoem structure of mitochondrial complex i from chaetomium thermophilum (state 1) - membrane arm
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Strain: dsm 1495 / cbs 144.50 / imi 039719. Strain: dsm 1495 / cbs 144.50 / imi 039719
Chain: S (74 residues)
8av6
Cryoem structure of ino80 core nucleosome complex in closed grappler conformation
Source: Thermochaetoides thermophila. Organism_taxid: 209285. Strain: dsm 1495 / cbs 144.50 / imi 039719. Gene: ctht_0006820. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: ctht_0006170. Gene: ctht_0004910. Gene: ctht_0032670.
Chains: A, B, C, D, E, F (449 residues)
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
8czt
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 15d
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (303 residues)
8czu
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 16d
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (303 residues)
8czv
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 17d
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (303 residues)
8dgy
Structure of mers 3cl protease in complex with the cyclopropane based inhibitor 16d (high resolution)
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (302 residues)
8e23
Human DNA polymerase theta in complex with allosteric inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Expressed in: synthetic construct.
Chains: A, D (637 residues)
8e24
Human DNA polymerase theta in complex with allosteric inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chains: A, D (644 residues)
8e6b
Crystal structure of mers 3cl protease in complex with a dimethyl sulfinyl benzene inhibitor
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
Chains: A, B (306 residues)
8e6c
Crystal structure of mers 3cl protease in complex with a m- fluorophenyl dimethyl sulfane inhibitor
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
Chain: A (302 residues)
8e6d
Crystal structure of mers 3cl protease in complex with a p- fluorophenyl dimethyl sulfane inhibitor
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
Chain: A (302 residues)
8e6e
Crystal structure of mers 3cl protease in complex with a phenyl sulfane inhibitor
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: bl21(de3).
Chain: A (306 residues)
8e7c
Crystal structure of porcine deltacoronavirus (hku-15) mpro with pfizer intravenous inhibitor pf-00835231
Source: Porcine deltacoronavirus. Organism_taxid: 1586324. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (301 residues)
8e7n
Crystal structure of beluga whale gammacoronavirus sw1 mpro with gc- 376 captured in two conformational states
Source: Beluga whale coronavirus sw1. Organism_taxid: 694015. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (299 residues)
8e7t
Crystal structure of middle east respiratory syndrome coronavirus (mers-cov) 3cl protease inactive mutant c148a
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (306 residues)
8eag
Ssomcm hexamer bound to mg/adp-befx and 12-mer oligo-dt. Class 2
Source: Saccharolobus solfataricus p2
Chains: A, B, C, D, E, F (161 residues)
8eai
Ssomcm hexamer bound to mg/adp-befx and 16-mer oligo-dt. Class 2
Source: Saccharolobus solfataricus p2
Chains: A, B, C, D, E, F (161 residues)
8eak
Ssomcm hexamer bound to mg/adp-befx and 46-mer DNA strand. Class 2
Source: Saccharolobus solfataricus p2
Chains: A, B, C, D, E, F (161 residues)
8eam
Ssomcm hexamer bound to mg/adp-befx and DNA. Class 2. Merged particles from datasets with 3 different DNA entities'
Source: Saccharolobus solfataricus p2
Chains: A, B, C, D, E, F (161 residues)
8fth
Chaetomium thermophilum setx - nppc internal deletion
Source: Thermochaetoides thermophila dsm 1495. Organism_taxid: 759272. Gene: ctht_0012480. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293f
Chain: A (1263 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8ftk
Chaetomium thermophilum setx (full-length)
Source: Thermochaetoides thermophila dsm 1495. Organism_taxid: 759272. Gene: ctht_0012480. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293f
Chain: A (1584 residues)
8ftm
Setx-ssrna-adp-so4 complex
Source: Chaetomium thermophilum. Organism_taxid: 759272. Gene: ctht_0012480. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Escherichia coli. Organism_taxid: 562
Chains: A, B (714 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8g6r
Porcine epidemic diarrhea virus core polymerase complex
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: orf1a, 1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: orf1. Synthetic: yes.
Chains: A, B, C (899 residues)
8gd7
Loop deleted DNA polymerase theta polymerase domain in complex with double strand DNA overhang and inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chain: A (631 residues)
8gh8
Ruva holliday junction DNA complex
Source: Thermus thermophilus hb8. Organism_taxid: 300852. Gene: ruva, ttha0291. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Organism_taxid: 32630
Chains: A, B, C, D (140 residues)
8gwe
Sars-cov-2 e-rtc complex with RNA-nsp9 and gmppnp
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: rep, 1a-1b. Expression_system_taxid: 469008
Chains: ( residues)
8h5y
Crystal structure of radd- adp complex
Source: Escherichia coli (strain k12). Organism_taxid: 83333. Gene: radd, yejh, yeji, yejj, b2184, jw2172. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chains: B, A (568 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8h5z
Crystal structure of radd/atp analogue complex
Source: Escherichia coli k-12. Organism_taxid: 83333. Gene: radd, yejh, yeji, yejj, b2184, jw2172. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chains: B, A (555 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
8hut
Crystal structure of mers main protease in complex with s217622
Source: Middle east respiratory syndrome-related coronavirus. Mers-cov. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chains: A, B (299 residues)
8huu
Crystal structure of hcov-nl63 main protease with s217622
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chains: A, B (296 residues)
8ig6
Crystal structure of mers main protease in complex with gc376
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Expression_system_cell_line: bl21
Chains: A, B (301 residues)
8im6
Crystal structure of hcov 229e main protease in complex with pf07304814
Source: Human coronavirus 229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (299 residues)
8j34
Crystal structure of mers main protease in complex with pf00835231
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: orf1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (299 residues)
8j90
Cryo-em structure of ddm1-nucleosome complex
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: htr2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: h2b. Synthetic construct. Organism_taxid: 32630.
Chain: K (504 residues)
8kcb
Complex of ddm1-nucleosome(h2a) complex with ddm1 bound to shl2
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: at5g22880, mrn17.11. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: htr2, at1g09200, t12m4.9, htr3, at3g27360, k1g2.8, htr13, at5g10390, f12b17_260, htr9, at5g10400, f12b17_250, htr1, at5g65360, mna5.9.
Chain: K (486 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8kcc
Complex of ddm1-nucleosome(h2a.W) complex with ddm1 bound to shl2
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: at5g59870, mmn10.22, mmn10_90. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: at5g22880, mrn17.11. Gene: htr2, at1g09200, t12m4.9, htr3, at3g27360, k1g2.8, htr13, at5g10390, f12b17_260, htr9, at5g10400, f12b17_250, htr1, at5g65360,
Chain: K (508 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8kg9
Yeast replisome in state iii
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: mcm2. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: atcc 204508 / s288c.
Chains: 2, 3, 4, 5, 6, 7 (668 residues)
Bound ligands:   Het Group AGS is 93.75% similar to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
8p62
S. Cerevisiae ssdna-scmge after DNA replication initiation
Source: Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Gene: mcm2, ybl023c, ybl0438. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Gene: mcm3, yel032w, sygp-orf23. Gene: mcm4, cdc54, hcd21, ypr019w, yp9531.13. Gene: mcm5, cdc46, ylr274w, l9328.1.
Chains: 2, 3, 4, 5, 6, 7 (662 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
8ppk
Bat-hp-cov nsp1 and eif1 bound to the human 40s small ribosomal subunit
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: eif1, sui1. Expressed in: escherichia coli. Expression_system_taxid: 562. Cell_line: hek293e. Cell_line: hek293. Bat hp-betacoronavirus/zhejiang2013.
Chain: j (174 residues)
8q67
Crystal structure of a homohexameric mcm from m. Acidophilum
Source: Candidatus mancarchaeum acidiphilum. Organism_taxid: 1920749. Gene: mia14_0611. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: plyss
Chains: A, B, C, D, E, F (574 residues)
8q6o
X. Laevis cmg dimer bound to dimeric donson - without atpase
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Organism_taxid: 8355
Chains: A, B, C, D, E, F, 2, 3, 4, 5, 6, 7 (267 residues)
8q6p
X. Laevis cmg dimer bound to dimeric donson - mcm atpase
Source: Xenopus laevis. African clawed frog. Organism_taxid: 8355. Organism_taxid: 8355
Chains: 2, 3, 4, 5, 6, 7 (431 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
8r5j
Crystal structure of mers-cov main protease
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: 1a. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chains: A, B (303 residues)
8rd3
Crystal structure of saccharomyces cerevisiae nmd4 protein bound to upf1 helicase domain
Source: Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Gene: nam7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: gold. Gene: nmd4. Expression_system_variant: gold
Chain: A (628 residues)
8rwv
Human occm DNA licensing intermediate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm2, bm28, ccnl1, cdcl1, kiaa0030. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: mcm3. Gene: mcm4, cdc21. Gene: mcm6.
Chains: 2, 3, 4, 6, 7 (653 residues)
8rxb
Human upf1 ch domain in complex with smg6 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: upf1, kiaa0221, rent1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
Chains: E, A, D, I, L, P (148 residues)
8s09
H. Sapiens mcm2-7 double hexamer bound to double stranded DNA
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm2, bm28, ccnl1, cdcl1, kiaa0030. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chains: 2, 3, 4, 5, 6, 7, A, B, C, D, E, F (692 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
8s0e
H. Sapiens occm bound to double stranded DNA
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm5, cdc46. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chains: 5, 2, 4, 6, 7, 3 (279 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
8s0f
H. Sapiens oc1m bound to double stranded DNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: orc2, orc2l. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chains: 5, 2, 4, 6, 7, 3 (279 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
8s52
RNA polymerase ii core initially transcribing complex with an ordered RNA of 10 nt
Source: Sus scrofa. Pig. Organism_taxid: 9823. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: R (222 residues)
8s55
RNA polymerase ii early elongation complex bound to tfiie and tfiif - state a (composite structure)
Source: Sus scrofa. Pig. Organism_taxid: 9823. Synthetic: yes. Unidentified adenovirus. Organism_taxid: 10535. Homo sapiens. Human. Organism_taxid: 9606.
Chain: R (137 residues)
8s5n
RNA polymerase ii core initially transcribing complex with an ordered RNA of 12 nt
Source: Sus scrofa. Pig. Organism_taxid: 9823. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2b, tf2b, tfiib. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: R (222 residues)
8s82
Restriction on ku inward translocation caps telomere ends
Source: Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Gene: yku70. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: yku80. Synthetic: yes. Synthetic construct.
Chains: K, L (557 residues)
8s8p
Restriction on ku inward translocation caps telomere ends
Source: Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Gene: yku70, hdf1, nes24, ymr284w, ym8021.10. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: K, L (557 residues)
8s91
Structure of walker b mutated mcm8/9 heterohexamer complex with adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm8, c20orf154. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: mcm9, c6orf61, mcmdc1. Expression_system_taxid: 7111
Chains: A, B, C, D, E, F (602 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8s92
Structure of n-terminal domains of walker b mutated mcm8/9 heterohexamer complex with adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm8, c20orf154. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: mcm9, c6orf61, mcmdc1. Expression_system_taxid: 7111
Chains: A, D, B, E, C, F (274 residues)
8s94
Structure of c-terminal domains of walker b mutated mcm8/9 heterohexamer complex with adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mcm8, c20orf154. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: mcm9, c6orf61, mcmdc1. Expression_system_taxid: 7111
Chains: A, D, C, F, B, E (328 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8skz
Cryo-em structure of ddm1-hells chimera bound to the nucleosome
Source: Arabidopsis thaliana, homo sapiens. Thale cress, human. Organism_taxid: 3702, 9606. Gene: ddm1, hells. Expressed in: escherichia coli. Expression_system_taxid: 562. Xenopus laevis. African clawed frog. Organism_taxid: 8355.
Chain: A (563 residues)
8t4s
Mers-cov nsp1 protein bound to the human 40s ribosomal subunit
Source: Homo sapiens. Human. Organism_taxid: 9606. Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: n (25 residues)
8th1
Crystal structure of the g3bp1 ntf2-like domain bound to the idr1 of sars-cov-2 nucleocapsid protein d3l mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Severe acute respiratory syndrome coronavirus 2.
Chains: A, B, C, D (137 residues)
8th5
Crystal structure of the g3bp1 ntf2-like domain bound to the idr1 of sars-cov-2 nucleocapsid protein p13l mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049.
Chains: A, B, C, D, E, F, G, H, I, J (123 residues)
8th6
Crystal structure of the g3bp1 ntf2-like domain bound to usp10 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: usp10, kiaa0190. Expression_system_taxid: 562
Chains: A, B, C, D (138 residues)
8th7
Crystal structure of the g3bp1 ntf2-like domain bound to the caprin1 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: caprin1, gpiap1, gpip137, m11s1, rng105. Expression_system_taxid: 562
Chains: A, B (134 residues)
8tvy
Cryo-em structure of cpd lesion containing RNA polymerase ii elongation complex with rad26 and elf1 (closed state)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: rad26. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chain: M (558 residues)
8urb
Porcine epidemic diarrhea virus complete core polymerase complex
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Gene: 1b, orf1a. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct.
Chains: A, B, C, D (921 residues)
8v1l
Crystal structure of the ntf2l domain of human g3bp1 in complex with small molecule
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (126 residues)
8vv2
Cryo-em structure of dhx36 bound to a RNA g-quadruplex derived from the cmyc g-quadruplex, class 1
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: dhx36. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Organism_taxid: 9606. Expressed in: synthetic construct.
Chain: A (852 residues)
8vvd
Cryo-em structure of dhx36 bound to a RNA g-quadruplex derived from the cmyc g-quadruplex, class 2
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: dhx36. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chain: A (850 residues)
8vx1
Cryo-em structure of dhx36 bound to the cmyc DNA g-quadruplex, class 2
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: dhx36. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chain: A (861 residues)
8vx8
Cryo-em structure of dhx36 bound to the cmyc DNA g-quadruplex, class 1
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: dhx36. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chain: A (843 residues)
8w0a
Human DNA polymerase theta helicase domain in complex with ssdna, dimer form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
Chains: C, A (636 residues)
8w7m
Yeast replisome in state v
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: mcm2. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Saccharomyces cerevisiae s288c. Organism_taxid: 559292. Strain: atcc 204508 / s288c.
Chains: 2, 3, 4, 5, 6, 7 (627 residues)
Bound ligands:   Het Group AGS is 93.75% similar to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
8wat
De novo transcribing complex 10 (tc10), the early elongation complex with pol ii positioned 10nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8wau
De novo transcribing complex 11 (tc11), the early elongation complex with pol ii positioned 11nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8wav
De novo transcribing complex 12 (tc12), the early elongation complex with pol ii positioned 12nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8waw
De novo transcribing complex 13 (tc13), the early elongation complex with pol ii positioned 13nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8wax
De novo transcribing complex 14 (tc14), the early elongation complex with pol ii positioned 14nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8way
De novo transcribing complex 15 (tc15), the early elongation complex with pol ii positioned 15nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8waz
De novo transcribing complex 16 (tc16), the early elongation complex with pol ii positioned 16nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8wb0
De novo transcribing complex 17 (tc17), the early elongation complex with pol ii positioned 17nt downstream of tss
Source: Amanita phalloides. Organism_taxid: 67723. Homo sapiens. Human. Organism_taxid: 9606. Gene: gtf2f1, rap74. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Chain: T (103 residues)
8wh5
Structure of ddm1-nucleosome complex in the apo state
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: htr2, at1g09200, t12m4.9, htr3, at3g27360, k1g2.8, htr13, at5g10390, f12b17_260, htr9, at5g10400, f12b17_250, htr1, at5g65360, mna5.9. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: at1g07660, f24b9.25, at1g07820, f24b9.8, at2g28740, f8n16.2,
Chain: K (445 residues)
8wh8
Structure of ddm1-nucleosome complex in adp state
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: htr2, at1g09200, t12m4.9, htr3, at3g27360, k1g2.8, htr13, at5g10390, f12b17_260, htr9, at5g10400, f12b17_250, htr1, at5g65360, mna5.9. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: at1g07660, f24b9.25, at1g07820, f24b9.8, at2g28740, f8n16.2,
Chain: K (443 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8wh9
Structure of ddm1-nucleosome complex in adp-befx state
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: htr2, at1g09200, t12m4.9, htr3, at3g27360, k1g2.8, htr13, at5g10390, f12b17_260, htr9, at5g10400, f12b17_250, htr1, at5g65360, mna5.9. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: at1g07660, f24b9.25, at1g07820, f24b9.8, at2g28740, f8n16.2,
Chain: K (452 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8wha
Structure of ddm1-nucleosome complex in the adp-befx state with ddm1 bound to shl2 and shl-2
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: htr2, at1g09200, t12m4.9, htr3, at3g27360, k1g2.8, htr13, at5g10390, f12b17_260, htr9, at5g10400, f12b17_250, htr1, at5g65360, mna5.9. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: at1g07660, f24b9.25, at1g07820, f24b9.8, at2g28740, f8n16.2,
Chains: K, L (452 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8x7t
Mcm in the apo state.
Source: Thermococcus kodakarensis. Organism_taxid: 311400. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: D, C, B, E, F, A (671 residues)
8x7u
Mcm in complex with dsdna in presence of atp.
Source: Thermococcus kodakarensis. Organism_taxid: 311400. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: D, C, B, E, A, F (654 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
8xa8
Cryo-em structure of bacillus rnap and held complex
Source: Bacillus. Organism_taxid: 1386. Gene: rpoa. Expressed in: bacillus subtilis. Expression_system_taxid: 1423. Gene: rpoc. Gene: rnpza. Gene: rpoz. Gene: held.
Chain: H (770 residues)
8xpi
Structure of thE C-terminal domain of nsp4 from pedv
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (90 residues)
8xvt
The core subcomplex of human nua4/tip60 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: expi293f. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Gene: dmap1, kiaa1425.
Chains: A, B, C, D, E, F (426 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
8y4f
Crystal structure of hcov 229e main protease in complex with bofutrelvir
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
Chains: A, B (298 residues)
8yjf
Structure of human spt16 md-ctd and mcm2 hbd chaperoning a histone h3- h4 tetramer and an h2a-h2b dimer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: supt16h, fact140, factp140. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: mcm2, bm28, ccnl1, cdcl1, kiaa0030. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi,
Chain: B (60 residues)
8yjm
Structure of human spt16 md-ctd and mcm2 hbd chaperoning a histone h3- h4 tetramer and a single chain h2b-h2a chimera
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: supt16h. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: mcm2, bm28, ccnl1, cdcl1, kiaa0030. Gene: h3c1, h3fa, hist1h3a, h3c2, h3fl, hist1h3b, h3c3, h3fc hist1h3c, h3c4, h3fb, hist1h3d, h3c6, h3fd, hist1h3e, h3c7, h3fi,
Chain: B (58 residues)
8zcc
Crystal structure of hcov-nl63 main protease with x77
Source: Human coronavirus nl63. Organism_taxid: 277944. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chains: A, B (298 residues)
9asj
Human DNA polymerase theta helicase domain in complex with amp-pnp, dimer form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (741 residues)
Bound ligand:   Het Group ANP is 81.25% similar to enzyme product ADP
9ask
Human DNA polymerase theta helicase domain dimer, apo-form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (741 residues)
9asl
Human DNA polymerase theta helicase domain tetramer, apo-form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (741 residues)
9au5
Ternary complex of human DNA polymerase theta polymerase domain with a cognate c:g base pair
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Organism_taxid: 9606
Chain: A (641 residues)
9au8
Ternary complex of human DNA polymerase theta polymerase domain with a mismatched t:t base pair
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Organism_taxid: 9606
Chain: A (641 residues)
9au9
Ternary complex of human DNA polymerase theta polymerase domain with a mismatched t:g base pair
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Organism_taxid: 9606
Chain: A (639 residues)
9bc5
Aav-2 rep68-aavs1 heptameric complex
Source: Adeno-associated virus 2. Organism_taxid: 10804. Gene: rep68. Expressed in: synthetic construct. Expression_system_taxid: 32630. Synthetic: yes. Homo sapiens. Organism_taxid: 9606. Organism_taxid: 9606
Chains: A, B, C, D, E, F, G (478 residues)
9bh6
Human DNA polymerase theta helicase domain tetramer in the apo form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chains: A, B, C, D (774 residues)
9bh7
Human DNA polymerase theta helicase domain dimer in the apo form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chains: A, B (772 residues)
9bh8
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta. Synthetic: yes. Synthetic construct.
Chains: A, B (787 residues)
9bh9
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta. Synthetic: yes. Synthetic construct.
Chains: A, B (787 residues)
9bha
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta. Synthetic: yes. Synthetic construct.
Chains: A, B (793 residues)
9bp9
Human DNA polymerase theta helicase domain in complex with inhibitor ab25583, dimer form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, C (741 residues)
9bpa
Human DNA polymerase theta helicase domain in complex with inhibitor ab25583, tetramer form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, C, E, G (739 residues)
9bu7
Cryo-em structure of aav2 rep68 bound to integration site aavs1: insights into the mechanism of DNA melting.
Source: Adeno-associated virus 2. Organism_taxid: 10804. Gene: rep68. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Homo sapiens. Organism_taxid: 9606. Other_details: sequence from chromosome 19
Chains: A, B, C, D, E, F, G (277 residues)
Bound ligand:   Het Group AGS is 93.75% similar to enzyme reactant ATP
9c57
Reconstituted p400 subcomplex of the human tip60 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: epc1. Gene: actl6a, baf53, baf53a, ino80k. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46.
Chains: E, B, C, D, F, A (437 residues)
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group AGS is 87.10% similar to enzyme product ADP
9c5q
Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Gene: polq, polh. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: C, A (775 residues)
9cc6
De novo design of high-affinity protein binders to RNA binding domain of g3bp1
Source: Synthetic construct. Organism_taxid: 32630. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
Chain: B (11 residues)
9cpo
Infectious bronchitis virus core polymerase complex
Source: Infectious bronchitis virus. Organism_taxid: 11120. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049.
Chains: A, B, C, D (930 residues)
9e2y
Cryo-em structure of yeast cmg helicase stalled at g4-containing DNA template, state 3
Source: Saccharomyces cerevisiae w303. Organism_taxid: 580240. Gene: psf1, ydr013w, pza208, yd8119.18. Expressed in: saccharomyces cerevisiae w303. Expression_system_taxid: 580240. Gene: psf2, yjl072c, hrf213, j1086. Gene: psf3, yol146w. Gene: sld5, ydr489w. Gene: cdc45, sld4, ylr103c, l8004.11.
Chains: 2, 3, 4, 5, 6, 7 (664 residues)
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group ADP corresponds to enzyme product ADP
9e6l
Cryo-em structure of yeast rad51 nucleoprotein filament bound to rad54peptide
Source: Synthetic: yes. Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Gene: rad51, yer095w. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: G, H, I, J, K (34 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
9emc
Ruvbl1/2 in complex with atp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ruvbl1, ino80h, nmp238, tip49, tip49a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ruvbl2, ino80j, tip48, tip49b, cgi-46. Expression_system_taxid: 562
Chains: A, D, B, C, F, E (322 residues)
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
9eq2
Arabidopsis thaliana r2t complex
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: rin1, rvb1, tip49a, at5g22330. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ise4, at5g67630, k9i9.20, k9i9_20. Gene: tpr5, tetratricopeptide repeat 5, at1g56440, f13n6.2, f13n6_2. Expression_system_taxid: 562
Chains: A, D, C, B, F, E (301 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
9f0x
Cryoem structure of the f plasmid relaxosome in its pre-initiation state, derived from the ds-27_+143-r locally-refined map 3.76 a
Source: Escherichia coli k-12. Organism_taxid: 83333. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ihfa, hid, hima, b1712, jw1702. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ihfb, himd, hip, b0912, jw0895. Gene: tray, ecok12f073.
Chain: H (266 residues)
9f0y
Cryoem structure of the f plasmid relaxosome with trai in its te mode, derived from the ss-27_+8ds+9_+143-r locally-refined 3.45 a map.
Source: Synthetic: yes. Escherichia coli k-12. Organism_taxid: 83333. Gene: ihfa, hid, hima, b1712, jw1702. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ihfb, himd, hip, b0912, jw0895. Gene: tray, ecok12f073. Gene: trai, ecok12f104.
Chain: H (561 residues)
9f0z
Cryoem structure of the f plasmid relaxosome with truncated trai1-863 in its te mode, derived from the ss-27_+8ds+9_+143-r_deltaah+ctd locally-refined 3.42 a map
Source: Synthetic: yes. Escherichia coli k-12. Organism_taxid: 83333. Gene: ihfa, hid, hima, b1712, jw1702. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ihfb, himd, hip, b0912, jw0895. Gene: tray, ecok12f073. Gene: trai, ecok12f104.
Chain: H (545 residues)
9f10
Cryoem structure of the f plasmid relaxosome with trai in its te mode, without accessory protein tram. Derived from the ss-27_+8ds+9_+143- r_deltatram locally-refined 2.94 a map.
Source: Synthetic: yes. Escherichia coli k-12. Organism_taxid: 83333. Gene: ihfa, hid, hima, b1712, jw1702. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ihfb, himd, hip, b0912, jw0895. Gene: tray, ecok12f073. Gene: trai, ecok12f104.
Chain: H (564 residues)
9f11
Cryoem structure of the f plasmid relaxosome with orit DNA ss- 27_+3ds+4_+143 and trai its te mode, derived from ss-27_+3ds+4_+143-r locally-refined 3.68 a map.
Source: Synthetic: yes. Escherichia coli k-12. Organism_taxid: 83333. Gene: ihfa, hid, hima, b1712, jw1702. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ihfb, himd, hip, b0912, jw0895. Gene: tray, ecok12f073. Gene: trai, ecok12f104.
Chain: H (543 residues)
9f12
Cryoem structure of the f plasmid relaxosome with orit DNA ss-27_-3ds- 2_+143 and trai its te mode, derived from ss-27_-3ds-2_+143-r locally-refined 3.42 a map.
Source: Synthetic: yes. Escherichia coli k-12. Organism_taxid: 83333. Gene: ihfa, hid, hima, b1712, jw1702. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ihfb, himd, hip, b0912, jw0895. Gene: tray, ecok12f073. Gene: trai, ecok12f104.
Chain: H (564 residues)
9imk
Sars-cov-2 replication-transcription complex has a dimer architecture (drtc) in post-capping state
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 2697049
Chains: ( residues)
9imm
Sars-cov-2 replication-transcription complex has a dimer architecture (local drtc) in post-capping state
Source: Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 2697049
Chains: ( residues)
9inm
Crystal structure of mers main protease in complex with bofutrelvir
Source: Middle east respiratory syndrome-related coronavirus. Organism_taxid: 1335626. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
Chains: A, B, C, D (301 residues)
9ivq
Cryo-em structure of the chikv nsp3 peptide in complex with the ntf2l domain of g3bp1 (conformation i)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Chikungunya virus. Organism_taxid: 37124. Expression_system_taxid: 562
Chains: A, C, D, B, P, N, M, O, T, R, Q, S, E, G, H, F (134 residues)
9ivr
Cryo-em structure of the chikv nsp3 peptide in complex with the ntf2l domain of g3bp1 (conformation ii)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Chikungunya virus. Organism_taxid: 37124. Expression_system_taxid: 562
Chains: A, C, D, B, P, N, M, O, T, R, Q, S, E, G, H, F (134 residues)
9ivs
Cryo-em structure of the chikv nsp3 peptide in complex with the ntf2l domain of g3bp1 (conformation iii)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Chikungunya virus. Organism_taxid: 37124. Expression_system_taxid: 562
Chains: A, C, D, B, P, N, M, O, T, R, Q, S, E, G, H, F (134 residues)
9j5s
Crystal structure of human g3bp1 in complex with chikv nsp3 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: g3bp1, g3bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Chikungunya virus. Chikv.
Chains: A, B (137 residues)
9jao
The structure of smarcad1 bound to the hexasome in the presence of adp-befx
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: smarcad1, kiaa1122. Expressed in: homo sapiens. Expression_system_taxid: 9606. Xenopus laevis. African clawed frog. Organism_taxid: 8355.
Chain: C (621 residues)
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
9juf
Pedv 3clpro mutant (c144a) in complex with nsp9|10 peptidyl substrate
Source: Porcine epidemic diarrhea virus. Organism_taxid: 28295. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 28295
Chains: A, B (298 residues)
9kbg
The structure of b19v ns1_2-570/amppnp
Source: Human parvovirus b19. Hpv b19. Organism_taxid: 10798. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H, I, J, K, L (291 residues)
9kbh
The structure of b19v ns1_2-570/ssdna/amppnp
Source: Human parvovirus b19. Organism_taxid: 10798. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Hpv b19. Organism_taxid: 10798
Chains: A, B, C, D, E, F (290 residues)
9kbi
The structure of b19v ns1_2-570/dsdna/amppnp
Source: Human parvovirus b19. Hpv b19. Organism_taxid: 10798. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10798
Chains: A, B, C, D, E, F, G, H, I, J, K, L (290 residues)
9kbj
The structure of b19v ns1_200-501/amppnp
Source: Human parvovirus b19. Hpv b19. Organism_taxid: 10798. Gene: ns1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, C, D, E, F, G, H, I, J, K, L, B (285 residues)
9qdq
Cryo-em structure of upf1-nmd4-ebs1 in complex with RNA
Source: Saccharomyces cerevisiae. Brewer's yeast. Organism_taxid: 4932. Gene: nam7, ifs2, mof4, upf1, ymr080c, ym9582.05c. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: ebs1, ydr206w, yd8142.03. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (797 residues)