_EC 3.5.3.27 arginine dihydrolase. 7 PDB entries  
EC 3.-.-.- Hydrolases. [51,972 PDB entries]
EC 3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds. [4,889 PDB entries]
EC 3.5.3.- In linear amidines. [317 PDB entries]
EC 3.5.3.27 arginine dihydrolase. [7 PDB entries]
6juy

Reaction: L-arginine + 2 H2O + 2 H(+) = L-ornithine + 2 NH4(+) + CO2.
 


L-arginine
+ 2 × H2O
+ 2 × H(+)
=
L-ornithine
+ 2 × NH4(+)
+
CO2
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The enzyme, characterized from different cyanobacterial species, is highly specific to arginine and does not require a metal cofactor. The enzyme from Nostoc is bifunctional, and also catalyzes the activity of Ec 4.3.1.12.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 7 PDB entries in enzyme class E.C.3.5.3.27

  PDB code Protein
6juy
Crystal structure of argz, apo structure, an arginine dihydrolase from the ornithine-ammonia cycle in cyanobacteria
Source: Synechocystis sp. (Strain pcc 6803 / kazusa). Organism_taxid: 1111708. Strain: pcc 6803 / kazusa. Gene: sll1336. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta
Chains: A, B, C, D (639 residues)
6juz
Crystal structure of n-terminal domain of argz(n71s) covalently bond to a reaction intermediate
Source: Synechocystis sp. (Strain pcc 6803 / kazusa). Organism_taxid: 1111708. Strain: pcc 6803 / kazusa. Gene: sll1336. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (272 residues)
6jv0
Crystal structure of n-terminal domain of argz, bound to product, an arginine dihydrolase from the ornithine-ammonia cycle in cyanobacteria
Source: Synechocystis sp. (Strain pcc 6803 / kazusa). Organism_taxid: 1111708. Strain: pcc 6803 / kazusa. Gene: sll1336. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chain: A (273 residues)
6jv1
Crystal structure of n-terminal domain of argz, c264s mutant, bound to substrate, an arginine dihydrolase from the ornithine-ammonia cycle in cyanobacteria
Source: Synechocystis sp. (Strain pcc 6803 / kazusa). Organism_taxid: 1111708. Strain: pcc 6803 / kazusa. Gene: sll1336. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chain: A (271 residues)
6lrf
Crystal structure of unliganded agre
Source: Nostoc sp. (Strain pcc 7120 / sag 25.82 / utex 2576). Organism_taxid: 103690. Strain: pcc 7120 / sag 25.82 / utex 2576. Gene: alr4995. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (671 residues)
6lrg
Crystal structure of the ternary complex of agre with ornithine and NAD+
Source: Nostoc sp. (Strain pcc 7120 / sag 25.82 / utex 2576). Organism_taxid: 103690. Strain: pcc 7120 / sag 25.82 / utex 2576. Gene: alr4995. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (678 residues)
6lrh
Crystal structure of the binary complex of agre c264a mutant with l- arginine
Source: Nostoc sp. (Strain pcc 7120 / sag 25.82 / utex 2576). Organism_taxid: 103690. Strain: pcc 7120 / sag 25.82 / utex 2576. Gene: alr4995. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (675 residues)