_EC 3.1.3.85 glucosyl-3-phosphoglycerate phosphatase.

5 PDB entries

EC 3.-.-.- Hydrolases. [51,972 PDB entries] EC 3.1.-.- Acting on ester bonds. [12,883 PDB entries] EC 3.1.3.- Phosphoric monoester hydrolases. [3,591 PDB entries] EC 3.1.3.85 glucosyl-3-phosphoglycerate phosphatase. [5 PDB entries]

4pz9

Reaction:		(2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + H2O = (2R)-2- O-(alpha-D-glucopyranosyl)-glycerate + phosphate.
		(2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + H2O = (2R)-2- O-(alpha-D-glucopyranosyl)-glycerate + phosphate Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments:		The enzyme is involved in biosynthesis of 2-O-(alpha-D- glucopyranosyl)-D-glycerate via the two-step pathway in which Ec 2.4.1.266 catalyzes the conversion of GDP-glucose and 3-phospho-D- glycerate into 2-O-(alpha-D-glucopyranosyl)-3-phospho-D-glycerate, which is then converted to 2-O-(alpha-D-glucopyranosyl)-D-glycerate by glucosyl-3-phosphoglycerate phosphatase. In vivo the enzyme catalyzes the dephosphorylation of 2-O-(alpha-D- mannopyranosyl)-3-phospho-D-glycerate with lower efficiency. Divalent metal ions (Mg(2+), Mn(2+) or Co(2+)) stimulate activity.
Links:		[IntEnz]   [ExPASy]   [KEGG]

There are 5 PDB entries in enzyme class E.C.3.1.3.85

PDB code		Protein
4pz9		The native structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase rv2419c Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: gpgp, mt2492, rv2419c. Expressed in: escherichia coli. Expression_system_taxid: 562. Chains: A, B (212 residues) CATH domain: 3.40.50.1240
4pza		The complex structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase rv2419c with inorganic phosphate Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: gpgp, mt2492, rv2419c. Expressed in: escherichia coli. Expression_system_taxid: 562. Chains: A, B (207 residues) CATH domain: 3.40.50.1240 Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
4qih		The structure of mycobacterial glucosyl-3-phosphoglycerate phosphatase rv2419c complexes with vo3 Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: gpgp, mt2492, rv2419c. Expressed in: escherichia coli. Expression_system_taxid: 562. Chains: A, B (209 residues) CATH domain: 3.40.50.1240
6s2q		Mycobacterial hydrolase 1 Source: Mycobacterium tuberculosis (strain atcc 25618 / h37rv). Organism_taxid: 83332. Strain: atcc 25618 / h37rv. Gene: gpgp, rv2419c. Expressed in: escherichia coli. Expression_system_taxid: 562 Chains: A, B, C, D (214 residues)
6s2r		Mycobacterial hydrolase 2 Source: Mycobacterium tuberculosis (strain atcc 25618 / h37rv). Organism_taxid: 83332. Strain: atcc 25618 / h37rv. Gene: gpgp, rv2419c. Expressed in: escherichia coli. Expression_system_taxid: 562 Chains: A, B (234 residues)