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PDB code
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Protein
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Protein tyrosine phosphatase 1b cysteinyl-phosphate intermediate
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Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: ba834. Cellular_location: er membrane. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: ba834.
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Chain:
A
(284 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with two bis(para-phosphophenyl)methane (bppm) molecules
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Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chain:
A
(297 residues)
CATH domain:
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Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase
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Source: Mus musculus. House mouse. Organism_taxid: 10090. Organism_taxid: 10090
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Chains:
A, B
(101 residues)
CATH domain:
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Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase
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Source: Mus musculus. House mouse. Organism_taxid: 10090. Organism_taxid: 10090
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Chain:
A
(100 residues)
CATH domain:
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Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase
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Source: Mus musculus. House mouse. Organism_taxid: 10090. Organism_taxid: 10090
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Chain:
A
(100 residues)
CATH domain:
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Crystal structures of peptide complexes of the amino-terminal sh2 domain of the syp tyrosine phosphatase
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Source: Mus musculus. House mouse. Organism_taxid: 10090
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Chain:
A
(101 residues)
CATH domain:
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Solution structure of a low molecular weight protein tyrosine phosphatase
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Source: Bos taurus. Cattle. Organism_taxid: 9913. Organ: heart. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(157 residues)
CATH domain:
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Human ptp1b catalytic domain complexed with tpi
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Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytoplasm. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(297 residues)
CATH domain:
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Cyclic peptide inhibitor of human ptp1b
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
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Chain:
A
(297 residues)
CATH domain:
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Human ptp1b complexed with tpicooh
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(297 residues)
CATH domain:
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Active site s19a mutant of bovine heart phosphotyrosyl phosphatase
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Source: Bos taurus. Cattle. Organism_taxid: 9913. Organ: heart. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B
(154 residues)
CATH domain:
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Bound ligand:
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Het Group PO4
corresponds to
enzyme product phosphate
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Human cdc25a catalytic domain
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Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Cellular_location: cytoplasm. Gene: cdc25a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chain:
A
(161 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with 6- (oxalyl-amino)-1h-indole-5-carboxylic acid
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with 3- (oxalyl-amino)-naphthalene-2-carboxlic acid
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with 2- (oxalyl-amino)-benzoic acid
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b (r47v,d48n) complexed with 2-(oxalyl-amino-4,7-dihydro-5h-thieno[2,3-c]pyran-3- carboxylic acid
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(296 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with 2- (oxalyl-amino-4,7-dihydro-5h-thieno[2,3-c]pyran-3-carboxylic acid
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with 2- (oxalyl-amino)-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of human prostatic acid phosphatase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Secretion: seminal fluid
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Chains:
A, B, C, D
(342 residues)
CATH domain:
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Bound ligand:
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Het Group NAG
is 60.00% similar to
enzyme product ribonucleoside
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Human cdc25b catalytic domain without ion in catalytic site
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Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytoplasm. Gene: cdc25b. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(178 residues)
CATH domain:
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Human cdc25b catalytic domain with tungstate
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Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytoplasm. Gene: cdc25b. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(179 residues)
CATH domain:
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Human cdc25b catalytic domain with methyl mercury
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Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytoplasm. Gene: cdc25b. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(178 residues)
CATH domain:
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Crystal structure of a yeast low molecular weight protein tyrosine phosphatase (ltp1)
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Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(156 residues)
CATH domain:
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Crystal structure of a yeast low molecular weight protein tyrosine phosphatase (ltp1) complexed with the substrate pnpp
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Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(159 residues)
CATH domain:
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Bound ligand:
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Het Group PO4
corresponds to
enzyme product phosphate
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Crystal structure of a yeast low molecular weight protein tyrosine phosphatase (ltp1) complexed with the activator adenine
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Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(156 residues)
CATH domain:
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Bound ligand:
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Het Group PO4
corresponds to
enzyme product phosphate
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Solution structure of the pdz2 domain from human phosphatase hptp1e complexed with a peptide
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
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Chain:
A
(96 residues)
CATH domain:
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Crystal structure of the pten tumor suppressor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five.
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Chain:
A
(307 residues)
CATH domains:
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Crystal structure of bovine low molecular weight ptpase complexed with hepes
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Source: Bos taurus. Cattle. Organism_taxid: 9913. Organ: heart. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(157 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with 5- iodo-2-(oxalyl-amino)-benzoic acid
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with acetyl-d-a-d-bpa-ptyr-l-i-p-q-q-g
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
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Chain:
A
(299 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with acetyl-e-l-e-f-ptyr-m-d-y-e-nh2
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of the complex formed between the catalytic domain of shp-1 and an in vitro peptide substrate py469 derived from shps-1.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. The sequence of this peptide occurs naturally in humans (homo sapiens)
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Chain:
A
(284 residues)
CATH domain:
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Crystal structure analysis of kinase associated phosphatase (kap) with a substitution of the catalytic site cysteine (cys140) to a serine
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: homo sapiens
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Chains:
A, B, C, D, E, F
(176 residues)
CATH domain:
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Crystal structure of kinase associated phosphatase (kap) in complex with phospho-cdk2
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: homo sapiens. Other_details: homo sapiens
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Chain:
A
(183 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with a tri-phosphorylated peptide (rdi(ptr)etd(ptr)(ptr)rk) from the insulin receptor kinase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: sequence from the activation segment of the insulin recptor kinase
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Chain:
A
(297 residues)
CATH domain:
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Bound ligand:
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Het Group PTR
is 76.19% similar to
enzyme reactant [protein]-L-tyrosine phosphate
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Crystal structure of protein tyrosine phosphatase 1b complexed with a mono-phosphorylated peptide (etdy(ptr)rkggkgll) from the insulin receptor kinase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: sequence from the activation segment of the insulin recptor kinase
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Chain:
A
(298 residues)
CATH domain:
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Crystal structure of protein tyrosine phosphatase 1b complexed with a bis-phosphorylated peptide (etd(ptr)(ptr)rkggkgll) from the insulin receptor kinase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: sequence from the activation segment of the insulin recptor kinase
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Chain:
A
(298 residues)
CATH domain:
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Bound ligand:
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Het Group PTR
is 76.19% similar to
enzyme reactant [protein]-L-tyrosine phosphate
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Crystal structure of the salmonella tyrosine phosphatase and gtpase activating protein sptp bound to rac1
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Source: Salmonella typhimurium. Organism_taxid: 602. Gene: sptp. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Homo sapiens. Human. Organism_taxid: 9606. Gene: rac1.
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Chain:
S
(360 residues)
CATH domains:
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Crystal structure of the salmonella tyrosine phosphatase and gtpase activating protein sptp
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Source: Salmonella typhimurium. Organism_taxid: 602. Gene: sptp. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
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Chain:
R
(341 residues)
CATH domains:
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Human ptp1b catalytic domain complexed with pnu177496
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(297 residues)
CATH domain:
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Human ptp1b catalytic domain complexes with pnu179326
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(297 residues)
CATH domain:
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Residue 259 is a key determinant of substrate specificity of protein- tyrosine phosphatase 1b and alpha
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(296 residues)
CATH domain:
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Second pdz domain (pdz2) of ptp-bl
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Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chain:
A
(94 residues)
CATH domain:
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Crystal structure of the catalytic domain of the protein tyrosine phosphatase shp-1
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(280 residues)
CATH domain:
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Crystal structure of the n-terminal domain of the tyrosine phosphatase yoph from yersinia pestis.
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Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(123 residues)
CATH domain:
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Structure of erk2 binding domain of mapk phosphatase mkp-3: structural insights into mkp-3 activation by erk2
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chain:
A
(154 residues)
CATH domain:
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Crystal structure of apo human ptp1b (c215s) mutant
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptn1_human. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chain:
A
(284 residues)
CATH domain:
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Human vh1-related dual-specificity phosphatase c124s mutant-peptide complex
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
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Chain:
A
(178 residues)
CATH domain:
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Solution structure of the sh3 domain from c-terminal src kinase complexed with a peptide from the tyrosine phosphatase pep
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Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
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Chain:
B
(18 residues)
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Human ptp1b catalytic domain complexed with pnu177836
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B
(281 residues)
CATH domain:
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Crystal structure of the catalytic domain of protein tyrosine phosphatase ptp-sl/br7
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Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(297 residues)
CATH domain:
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Structure of the salmonella virulence effector sptp in complex with its secretion chaperone sicp
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Source: Salmonella typhimurium. Organism_taxid: 602. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Pharmacia vector.
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Chains:
E, F
(102 residues)
CATH domain:
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Crystal structure of the type iii secretory domain of yersinia yoph reveals a domain-swapped dimer
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Source: Yersinia pseudotuberculosis. Organism_taxid: 633. Gene: yoph. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chain:
A
(124 residues)
CATH domain:
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Human tyrosine phosphatase 1b complexed with an inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
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Chain:
A
(297 residues)
CATH domain:
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Human tyrosine phosphatase 1b complexed with an inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(297 residues)
CATH domain:
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Crystal structure of ptp1b complexed with 7-(1,1-dioxo-1h- benzo[d]isothiazol-3-yloxymethyl)-2-(oxalyl-amino)-4,7-dihydro-5h- thieno[2,3-c]pyran-3-carboxylic acid
|
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|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
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T cell protein-tyrosine phosphatase structure
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(273 residues)
CATH domain:
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Crystal structure of the tandem phosphatase domains of rptp lar
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: de3
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Chains:
A, B
(566 residues)
CATH domains:
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Structure of ptp1b in complex with a peptidic bisphosphonate inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B, C, D
(287 residues)
CATH domain:
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High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase c403a mutant in complex with phosphate.
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Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chain:
A
(283 residues)
CATH domain:
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Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
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Nmr structure of the type iii secretory domain of yersinia yoph complexed with the skap-hom phospho-peptide n-acetyl-depyddpf-nh2
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Source: Yersinia pseudotuberculosis. Organism_taxid: 633. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this peptide was chemically synthesized. It is naturally found in mus musculus (mouse).
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Chain:
A
(130 residues)
CATH domain:
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Solution structure of the catalytic domain of mapk phosphatase pac-1: insights into substrate-induced enzymatic activation
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|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(145 residues)
CATH domain:
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Crystal structure of pyst1 (mkp3)
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|
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(144 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: semen
|
|
|
Chains:
A, B, C, D
(342 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: semen
|
|
|
Chains:
A, B, C, D
(342 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Potent, selective protein tyrosine phosphatase 1b inhibitor compound 12 using a linked-fragment strategy
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Potent, selective protein tyrosine phosphatase 1b inhibitor compound 23 using a linked-fragment strategy
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Potent, selective protein tyrosine phosphatase 1b inhibitor compound 5 using a linked-fragment strategy
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Ptp1b r47c modified at c47 with n-[4-(2-{2-[3-(2-bromo-acetylamino)- propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(296 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ptp1b complexed with sp7343-sp7964, a ptyr mimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Potent, selective inhibitors of protein tyrosine phosphatase 1b using a second phosphotyrosine binding site, complexed with compound 19.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Ptp1b with the catalytic cysteine oxidized to a sulfenyl-amide bond
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
X
(281 residues)
CATH domain:
|
|
|
|
|
|
Ptp1b with the catalytic cysteine oxidized to sulfonic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
X
(281 residues)
CATH domain:
|
|
|
|
|
|
Oxidation state of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Oxidation state of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Other_details: residues 1-321
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Oxidation state of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Oxidation state of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Structure of the proline directed phosphatase cdc14
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
|
|
|
Chain:
A
(339 residues)
CATH domains:
|
|
|
|
|
|
Structure of cdc14 in complex with tungstate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
|
|
|
Chain:
A
(338 residues)
CATH domains:
|
|
|
|
|
|
Structure of cdc14b phosphatase with a peptide ligand
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Synthetic: yes. Escherichia coli. Organism_taxid: 562
|
|
|
Chain:
A
(339 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group SEP
is 50.00% similar to
enzyme product phosphate
|
|
|
|
|
|
|
Oxalyl-aryl-amino benzoic acid inhibitors of ptp1b, compound 17
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Oxalyl-aryl-amino benzoic acid inhibitors of ptp1b, compound 8b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
The alternatively spliced pdz2 domain of ptp-bl
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ptp-bl. Expressed in: escherichia coli. Expression_system_taxid: 562. Competent.
|
|
|
Chain:
A
(99 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the d2 domain of rptpa
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ptpra or lrp or ptpa. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(245 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the low molecular weight protein tyrosine phosphatase from tritrichomonas foetus
|
|
|
Source: Tritrichomonas foetus. Organism_taxid: 5724. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(146 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the c215d mutant of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(302 residues)
CATH domain:
|
|
|
|
|
|
Yersinia protein-tyrosine phosphatase complexed with pncs (yop51, pasteurella x,ptpase,yop51delta162) (catalytic domain, residues 163- 468) mutant with cys 235 replaced by arg (c235r)
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph or yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(279 residues)
CATH domain:
|
|
|
|
|
|
Non-carboxylic acid-containing inhibitor of ptp1b targeting the second phosphotyrosine site
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
The crystal structure of a low molecular phosphotyrosine protein phosphatase
|
|
|
Source: Bos taurus. Cattle. Organism_taxid: 9913
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of bovine heart phosphotyrosyl phosphatase at 2.2 angstroms resolution
|
|
|
Source: Bos taurus. Cattle. Organism_taxid: 9913
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b complexed with phosphotyrosine-containing tetra-peptide (ac-depyl-nh2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b complexed with phosphotyrosine-containing hexa-peptide (dadepyl-nh2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PTR
is 76.19% similar to
enzyme reactant [protein]-L-tyrosine phosphate
|
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b complexed with phosphotyrosine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b complexed with two phosphotyrosine molecules
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b with potent and selective bidentate inhibitor compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Dual-site potent, selective protein tyrosine phosphatase 1b inhibitor using a linked fragment strategy and a malonate head on the first site
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
A highly efficient approach to a selective and cell active ptp1b inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(299 residues)
CATH domain:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(289 residues)
CATH domain:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 9
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(289 residues)
CATH domain:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 11
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(289 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the alternatively spliced pdz2 domain (pdz2b) of ptp-bas (hptp1e)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1e. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(108 residues)
CATH domain:
|
|
|
|
|
|
Human cdc25b catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytoplasm. Gene: cdc25b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(178 residues)
CATH domain:
|
|
|
|
|
|
Monoacid-based, cell permeable, selective inhibitors of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1 or ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the yersinia pestis phosphatase yoph in complex with a phosphotyrosyl mimetic-containing hexapeptide
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
|
|
|
Chains:
A, B
(282 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of human prl-3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(172 residues)
CATH domain:
|
|
|
|
|
|
Three-dimensional structure of rat acid phosphatase in complex with l(+) tartrate
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116
|
|
|
Chain:
A
(342 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase mu, domain 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(278 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of rat acid phosphatase complexed with the transitions state analogs vanadate and molybdate: implications for the reaction mechanism
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116
|
|
|
Chain:
A
(342 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase 4a1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(150 residues)
CATH domain:
|
|
|
|
|
|
1.95 a structure of apo protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure of a cdc25-like dual-specificity tyrosine phosphatase of arabidopsis thaliana
|
|
|
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: cdc25. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(132 residues)
CATH domain:
|
|
|
|
|
|
Allosteric inhibition of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(292 residues)
CATH domain:
|
|
|
|
|
|
Allosteric inhibition of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Allosteric inhibition of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mycobacterium tuberculosis low molecular protein tyrosine phosphatase (mptpa) at 1.9a resolution
|
|
|
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: mptpa. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(156 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mycobacterium tuberculosis low molecular weight protein tyrosine phosphatase (mptpa) at 2.5a resolution with glycerol in the active site
|
|
|
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: mptpa. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(155 residues)
CATH domain:
|
|
|
|
|
|
Magnesium dependent phosphatase 1 (mdp-1)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: af230273. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(163 residues)
CATH domain:
|
|
|
|
|
|
X-ray crystal structure of the hypothetical phosphotyrosine phosphatase mdp-1 of the haloacid dehalogenase superfamily
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: af230273. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(164 residues)
CATH domain:
|
|
|
|
|
|
Structure of human prl-3, the phosphatase associated with cancer metastasis
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(162 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of cold-active protein-tyrosine phosphatase of a psychrophile shewanella sp.
|
|
|
Source: Shewanella sp.. Organism_taxid: 50422. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(331 residues)
CATH domain:
|
|
|
|
|
|
Human vh1-related dual-specificity phosphatase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Other_details: original gene gdb\:dusp3. Vhr, chromosome map position 17q21
|
|
|
Chains:
A, B
(178 residues)
CATH domain:
|
|
|
|
|
|
Pdz2 from ptp-bl in complex with thE C-terminal ligand from the apc protein
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ptp-bl. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this protein has been chemically synthesized. It is present in mouse.
|
|
|
Chain:
A
(95 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with active site inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: de3.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpl1 human tyrosine phosphatase mutated in colorectal cancer - evidence for a second phosphotyrosine substrate recognition pocket
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(308 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of jsp-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(156 residues)
CATH domain:
|
|
|
|
|
|
Prl-1 (ptp4a)
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(152 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the fibronectin type-iii domain of human protein tyrosine phosphatase, receptor type, d isoform 4 variant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprd. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(115 residues)
CATH domain:
|
|
|
|
|
|
Solution structures of the sh2 domain of human protein-tyrosine phosphatase shp-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn6. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(118 residues)
CATH domain:
|
|
|
|
|
|
Ptp1b complexed with isoxazole carboxylic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(299 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human prl-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F
(149 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human b-form low molecular weight phosphotyrosyl phosphatase at 1.6 angstrom resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Yersinia yoph (residues 163-468) c403s binds phosphotyrosyl peptide at two sites
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized.
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
Yersinia yoph (residues 163-468) binds phosphonodifluoromethyl-phe containing hexapeptide at two sites
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemically synthesized by robert zamboni and michael gresser, merck frosst, montreal
|
|
|
Chains:
A, B
(282 residues)
CATH domain:
|
|
|
|
|
|
Receptor protein tyrosine phosphatase alpha, domain 1 from mouse
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell_line: bl21. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: bl21. Other_details: type i membrane protein
|
|
|
Chains:
A, B
(279 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tandem phosphatase domain of rptp cd45
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chains:
A, B
(574 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tandem phosphatase domains of rptp cd45 with a ptyr peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprc, cd45. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: polyoma middle t antigen ptyr peptide
|
|
|
Chains:
A, B
(571 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the cdc25b phosphatase catalytic domain with the active site cysteine in the sulfinic form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the cdc25b phosphatase catalytic domain with the active site cysteine in the sulfonic form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the cdc25b phosphatase catalytic domain in the apo form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the cdc25b phosphatase catalytic domain with the active site cysteine in the sulfenic form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of baculovirus RNA 5'-phosphatase complexed with phosphate
|
|
|
Source: Autographa californica nucleopolyhedrovirus. Organism_taxid: 46015. Gene: ptp. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(168 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of yersinia protein tyrosine phosphatase at 2.5 angstroms and the complex with tungstate
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yop51.
|
|
|
Chains:
A, B
(278 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the cdc25b phosphatase catalytic domain with the active site cysteine in the disulfide form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Hydrolase
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Strain: w22703. Cell_line: bl21. Gene: yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
A ligand-induced conformational change in the yersinia protein tyrosine phosphatase
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Strain: w22703. Gene: yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(278 residues)
CATH domain:
|
|
|
|
|
|
Yersinia ptpase complexed with tungstate
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Strain: w22703. Cell_line: bl21. Gene: yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of dusp15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(159 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of bovine low molecular weight ptpase complexed with vanadate
|
|
|
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of bovine low molecular weight ptpase complexed with molybdate
|
|
|
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human hematopoietic tyrosine phosphatase (heptp) catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(286 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Native structure prl-1 (ptp4a1)
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(150 residues)
CATH domain:
|
|
|
|
|
|
Prl-1 c104s mutant in complex with sulfate
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(152 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of catalytic domain of human map kinase phosphatase 5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(147 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of an active site mutant, c473s, of cdc25b phosphatase catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(171 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human protein tyrosine phosphatase, ptpn7 (heptp, hematopoietic protein tyrosine phosphatase)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(272 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the catalytic domain of human tyrosine phosphatase receptor, type r
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprr, ecptp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of human tyrosine receptor phosphatase beta
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(281 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b with bicyclic thiophene inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b with tricyclic thiophene inhibitor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human tyrosine phosphatase shp-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn6, hcp, ptp1c. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(504 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the catalytic domain of protein tyrosine phosphatase, non-receptor type 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(259 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of a complex between ptp1b and the insulin receptor tyrosine kinase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: insr. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chains:
A, C
(289 residues)
CATH domain:
|
|
|
|
|
|
Structure-based design of protein tyrosine phosphatase-1b inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(295 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Structure-based design of protein tyrosine phosphatase-1b inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human protein tyrosine phosphatase ptpn5 (step, striatum enriched enriched phosphatase)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organ: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human protein tyrosine phosphatase ptpn5 at 1.8a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organ: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human protein tyrosine phosphatase n14 at 1. 65 a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase kappa at 1.95a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the mam-ig module of receptor protein tyrosine phosphatase mu
|
|
|
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek-293t.
|
|
|
Chain:
A
(259 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group NAG
is 47.62% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase receptor type j
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(268 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the c472s mutant of human protein tyrosine phosphatase ptpn5 (step, striatum enriched phosphatase) in complex with phosphotyrosine
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(275 residues)
CATH domain:
|
|
|
|
|
|
Structure of protein tyrosine phosphatase 1b (p212121)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
|
|
Structure of protein tyrosine phosphatase 1b (c2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(275 residues)
CATH domain:
|
|
|
|
|
|
Structural basis for inhibition of protein tyrosine phosphatase 1b by isothiazolidinone heterocyclic phosphonate mimetics
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Structural basis for inhibition of protein tyrosine phosphatase 1b by isothiazolidinone heterocyclic phosphonate mimetics
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Structural basis for inhibition of protein tyrosine phosphatase 1b by isothiazolidinone heterocyclic phosphonate mimetics
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Structural basis for inhibition of protein tyrosine phosphatase 1b by isothiazolidinone heterocyclic phosphonate mimetics
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(287 residues)
CATH domain:
|
|
|
|
|
|
Structural basis for inhibition of protein tyrosine phosphatase 1b by isothiazolidinone heterocyclic phosphonate mimetics
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(286 residues)
CATH domain:
|
|
|
|
|
|
Structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(287 residues)
CATH domain:
|
|
|
|
|
|
Structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(300 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of rsgi ruh-031, a uba domain from human cdna
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: genbank/ab075839. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(64 residues)
|
|
|
|
|
|
Solution structure of pdz domain of protein tyrosine phosphatase, non- receptor type 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(119 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of tt1001 protein from thermus thermophilus hb8
|
|
|
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(150 residues)
CATH domain:
|
|
|
|
|
|
Solution structures of the fn3 domain of human receptor-type tyrosine- protein phosphatase f
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(106 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the ptb domain of kiaa1075 protein from human
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tenc1. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(160 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the fourth fn3 domain of human receptor-type tyrosine-protein phosphatase eta
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprj, dep1. Expressed in: cell free synthesis. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(104 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the second fn3 domain of human receptor-type tyrosine-protein phosphatase delta
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprd. Expressed in: cell free synthesis. Other_details: cell free protein synthesis
|
|
|
Chain:
A
(121 residues)
CATH domain:
|
|
|
|
|
|
Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase f
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf, lar. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(107 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex of the archaeal sulfolobus ptp-fold phosphatase with phosphopeptides a-(p)y-r
|
|
|
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: synthetic peptide
|
|
|
Chain:
A
(158 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of catalytic domain of dual specificity phosphatase 26, ms0830 from homo sapiens
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(150 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of sh3 domain in suppressor of t-cell receptor signaling 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: sts1. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(94 residues)
CATH domain:
|
|
|
|
|
|
Solution structures of the fn3 domain of human receptor-type tyrosine- protein phosphatase f
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(134 residues)
CATH domain:
|
|
|
|
|
|
Solution structures of the fn3 domain of human receptor-type tyrosine- protein phosphatase f
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf. Other_details: cell-free protein synthesis
|
|
|
Chain:
A
(103 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human dusp18
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(162 residues)
CATH domain:
|
|
|
|
|
|
The structure of the s295f mutant of human ptp1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(302 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Structure of a protein tyrosine phosphatase
|
|
|
Source: Escherichia coli k12. Organism_taxid: 83333. Strain: k-12. Gene: wzb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(147 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the phosphatase domains of human ptp sigma
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprs. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(568 residues)
CATH domains:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(285 residues)
CATH domain:
|
|
|
|
|
|
The structure of phosphotyrosine phosphatase 1b in complex with compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(289 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of erk2 complex with kim peptide derived from mkp3
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: mapk1, erk2, mapk, prkm1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: chemically synthesized.
|
|
|
Chains:
D, C
(11 residues)
|
|
|
|
|
|
Crystal structure of the catalytic domain of protein tyrosine phosphatase from homo sapiens
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpro, glepp1, ptpu2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of human dusp5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(147 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the low molecular weight protein tyrosine phosphatase from campylobacter jejuni.
|
|
|
Source: Campylobacter jejuni. Organism_taxid: 197. Strain: 11168. Gene: cj1258. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(156 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human receptor phosphatase ptpro
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpro, glepp1, ptpu2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(295 residues)
CATH domain:
|
|
|
|
|
|
Heptp catalytic domain (residues 44-339), s225d mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(288 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Docking motif interactions in the map kinase erk2
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: erk2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chain:
B
(16 residues)
|
|
|
|
|
|
Crystal structure of tmdp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp13, tmdp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(169 residues)
CATH domain:
|
|
|
|
|
|
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(278 residues)
CATH domain:
|
|
|
|
|
|
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(288 residues)
CATH domain:
|
|
|
|
|
|
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(280 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the pgm domain of the suppressor of t-cell receptor (sts-1)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: sts-1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(261 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b with monocyclic thiophene inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b with a monocyclic thiophene inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human tyrosine receptor phosphatase gamma
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(278 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b with monocyclic thiophene inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Engineered catalytic domain of protein tyrosine phosphatase hptpbeta.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(290 residues)
CATH domain:
|
|
|
|
|
|
Engineered protein tyrosine phosphatase beta catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mouse putative dual specificity phosphatase complexed with zinc tungstate, new york structural genomics consortium
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: 0710001b24rik. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(159 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: 293.
|
|
|
Chain:
A
(278 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: 293.
|
|
|
Chain:
A
(278 residues)
CATH domain:
|
|
|
|
|
|
Structural origins of l(+)-tartrate inhibition of human prostatic acid phosphatase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: isolated from human seminal fluid
|
|
|
Chains:
A, B, C, D
(342 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the heptp catalytic domain c270s mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(285 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the human phosphatase (dusp9)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp9, mkp4. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(144 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the human tyrosine receptor phosphate gamma in complex with vanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprg. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(276 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the phosphatase domain of human ptp ia-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprn, ica3, ica512. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
Engineered catalytic domain of protein tyrosine phosphatase hptpbeta
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(286 residues)
CATH domain:
|
|
|
|
|
|
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(276 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of yersinia protein tyrosine phosphatase complexed with vanadate, a transition state analogue
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Strain: w22703. Gene: yoph, yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(281 residues)
CATH domain:
|
|
|
|
|
|
Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with a sulfamic acid (soaking experiment)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(280 residues)
CATH domain:
|
|
|
|
|
|
Engineering the ptpbeta catalytic domain with improved crystallization properties
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(280 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex of the archaeal sulfolobus ptp-fold phosphatase with phosphate ion
|
|
|
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(161 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the complexes of the archaeal sulfolobus ptp-fold phosphatase with tungstate
|
|
|
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(161 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex of the archaeal sulfolobus ptp-fold phosphatase with phosphopeptides n-g-(p)y-k-n
|
|
|
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: synthetic peptide
|
|
|
Chain:
A
(158 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex of the archaeal sulfolobus ptp-fold phosphatase with pnpp
|
|
|
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(159 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase n4 (ptpn4)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(273 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of a remote binding site mutant, r492l, of cdc25b phosphatase catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(175 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of an active site mutant, c473d, of cdc25b phosphatase catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(175 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mouse sts-1 pgm domain in complex with phosphate
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: sts-1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, M
(262 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of dual specificity protein phosphatase 23 from homo sapiens in complex with ligand malate ion
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp23. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(149 residues)
CATH domain:
|
|
|
|
|
|
Apo & sulphate bound forms of sdp-1
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: s288c / ab972. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
|
|
|
Chains:
A, B
(134 residues)
CATH domain:
|
|
|
|
|
|
Ptyr bound form of sdp-1
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: s288c / ab972. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
|
|
|
Chains:
A, B
(145 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PTR
is 45.45% similar to
enzyme product phosphate
|
|
|
|
|
|
|
Protein tyrosine phosphatase, receptor type, e isoform
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
|
|
|
Chains:
A, B, C, D, E, F
(537 residues)
CATH domains:
|
|
|
|
|
|
Solution structure of par-3 pdz3 in complex with pten peptide
|
|
|
Source: Rattus norvegicus. Rat. Gene: pard3, par3. Expressed in: escherichia coli. Gene: pten, pten/mmac1.
|
|
|
Chain:
B
(11 residues)
|
|
|
|
|
|
Nmr solution structure of sh2 domain of the human tensin like c1 domain containing phosphatase (tenc1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa1075, tenc1, tensin like c1 domain containing phosphatase, tns2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of mast2-pdz complexed with thE C-terminus of pten
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide
|
|
|
Chain:
B
(13 residues)
|
|
|
|
|
|
An arsenate reductase in the reduced state
|
|
|
Source: Synechocystis. Organism_taxid: 1148. Strain: pcc 6803. Gene: arsc, slr0946. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
An arsenate reductase in the phosphate binding state
|
|
|
Source: Synechocystis. Organism_taxid: 1148. Strain: pcc 6803. Gene: arsc, slr0946. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
An arsenate reductase in the intermediate state
|
|
|
Source: Synechocystis. Organism_taxid: 1148. Strain: pcc 6803. Gene: arsc, slr0946. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
Nmr structure in a membrane environment reveals putative amyloidogenic regions of the sevi precursor peptide pap248-286
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: acpp
|
|
|
Chain:
A
(39 residues)
|
|
|
|
|
|
Solution structure of a nonphosphorylated peptide recognizing domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(115 residues)
CATH domain:
|
|
|
|
|
|
Solution nmr structure of pap248-286 in 50% tfe
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: purchased from from a vendor
|
|
|
Chain:
A
(39 residues)
|
|
|
|
|
|
Solution nmr structure of pap248-286 in 30% tfe
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: purchased from from a vendor
|
|
|
Chain:
A
(39 residues)
|
|
|
|
|
|
The novel binding mode of dlc1 and tensin2 ptb domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tenc1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: dlc1.
|
|
|
Chain:
A
(147 residues)
CATH domain:
|
|
|
|
|
|
Nmr solution structure of apo-mptpa
|
|
|
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: ptpa, rv2234, mt2293, mtcy427.15. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss. Other_details: original pet16btev vector was double ncoi/blpid digested and cloned into the modified pkm263 (6xhis tag protgb1-tev between nde1 and xho1) vector
|
|
|
Chain:
A
(164 residues)
CATH domain:
|
|
|
|
|
|
Cis form of a photoswitchable pdz domain crosslinked with an azobenzene derivative
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(97 residues)
CATH domain:
|
|
|
|
|
|
Trans form of a photoswitchable pdz domain crosslinked with an azobenzene derivative
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(97 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of tyrosine phosphatase related to biofilm formation a (tpba) from pseudomonas aeruginosa
|
|
|
Source: Pseudomonas aeruginosa. Organism_taxid: 208963. Strain: ucbpp-pa14. Gene: pa14_13660. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(193 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of human holo-prl-3 in complex with vanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a3, prl3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(162 residues)
CATH domain:
|
|
|
|
|
|
Pap262-270 in sds micelles
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chain:
A
(11 residues)
|
|
|
|
|
|
An arsenate reductase in reduced state
|
|
|
Source: Synechocystis sp.. Organism_taxid: 1111708. Strain: pcc 6803. Gene: arsc, slr0946. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
An arsenate reductase in the phosphate binding state
|
|
|
Source: Synechocystis sp.. Organism_taxid: 1111708. Strain: pcc 6803. Gene: arsc, slr0946. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
An arsenate reductase in the intermediate state
|
|
|
Source: Synechocystis sp.. Organism_taxid: 1111708. Strain: pcc 6803. Gene: arsc, slr0946. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
An arsenate reductase in oxidized state
|
|
|
Source: Synechocystis sp.. Organism_taxid: 1111708. Strain: pcc 6803. Gene: arsc, slr0946. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(131 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of d1 and d2 catalytic domains of human protein tyrosine phosphatase gamma (d1+d2 ptprg)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(553 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of slingshot phosphatase 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ssh2, kiaa1725, ssh2l. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C
(142 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b-inhibitor complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b-inhibitor complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of a c-terminal phosphatase domain of rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, d (ptprd)
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: ptprd. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C
(283 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ptprj inactivating mutant c1239s
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprj. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(296 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the catalytic domain of human protein tyrosine phosphatase non-receptor type 18
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn18. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(279 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human receptor phosphatase ptprt
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprt, kiaa0283. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(278 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the map kinase binding domain of mkp5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mkp5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(132 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of human mkp5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mkp5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(177 residues)
CATH domain:
|
|
|
|
|
|
Structure-assisted discovery of variola major h1 phosphatase inhibitors
|
|
|
Source: Variola virus. Organism_taxid: 10255. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(163 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of acid phosphatase 1 (acp1) from mus musculus
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Strain: fvb/n. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(153 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of human tyrosine phosphatase ptpn22
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(302 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase ptpn9
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(296 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human tyrosine receptor phosphate gamma
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprg. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(285 residues)
CATH domain:
|
|
|
|
|
|
Structure of the catalytic domain of the chick retinal neurite inhibitor-receptor protein tyrosine phosphatase cryp-2/cptpro
|
|
|
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: cryp2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(294 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of dual specificity protein phosphatase 13 (dusp13)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp13, tmdp. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(169 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of tyr/ser protein phosphatase from vaccinia virus wr
|
|
|
Source: Vaccinia virus wr. Organism_taxid: 10254. Strain: wr (western reserve), vacv. Gene: h1l, vacwr099. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(181 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b-inhibitor complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b-inhibitor complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b-inhibitor complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b-inhibitor complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Native structure of lyp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(280 residues)
CATH domain:
|
|
|
|
|
|
Structure of lyp with inhibitor i-c11
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the heptp catalytic domain d236a mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the heptp catalytic domain c270s/d236a/q314a mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(286 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the heptp catalytic domain c270s mutant crystallized in ammonium acetate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(292 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the d1 domain of ptprn2 (ia2beta)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprn2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(288 residues)
CATH domain:
|
|
|
|
|
|
Crystallographic structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase ia-2 at 1.30 angstroms
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprn, ica3, ica512. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(89 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the vaccinia virus dual-specificity phosphatase vh1
|
|
|
Source: Vaccinia virus. Organism_taxid: 10245. Strain: western reserve/wr. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(170 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the shp-1 c-terminal sh2 domain complexed with a tyrosine-phosphorylated peptide from nkg2a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn6, hcp, ptp1c. Expressed in: cell-free synthesis. Other_details: e. Coli cell-free. Synthetic: yes. Other_details: peptide synthetic. This sequence occurs naturally in humans
|
|
|
Chain:
A
(118 residues)
CATH domain:
|
|
|
|
|
|
Tyrosine phosphatase shp-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(491 residues)
CATH domains:
|
|
|
|
|
|
Protein phosphatase, new crystal form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(172 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Organ: lung. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek-293s gnti-.
|
|
|
Chain:
A
(564 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b in complex with an isothiazolidinone-containing inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b in complex with an isothiazolidinone-containing inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(299 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b in complex with an isothiazolidinone-containing inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b in complex with an isothiazolidinone-containing inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b in complex with an isothiazolidinone-containing inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, pdz domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-rosetta-prare2.
|
|
|
Chains:
A, B
(98 residues)
CATH domain:
|
|
|
|
|
|
The structure of the rhodanese domain of the human dual specificity phosphatase 16
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(134 residues)
CATH domain:
|
|
|
|
|
|
Mona sh3c in complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 10090
|
|
|
Chain:
D
(12 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of human dual specificity phosphatase 14
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(168 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase wzb from escherichia coli k30 in complex with phosphate.
|
|
|
Source: Escherichia coli. Organism_taxid: 562. Strain: k30. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(146 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase cps4b from steptococcus pneumoniae tigr4.
|
|
|
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: tigr 4. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(244 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase cps4b from steptococcus pneumoniae tigr4.
|
|
|
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: tigr 4. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(244 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase cps4b from steptococcus pneumoniae tigr4 in complex with phosphate.
|
|
|
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: tigr 4. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(244 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (mgc5987)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(170 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase wzb from escherichia coli k30 in complex with sulphate.
|
|
|
Source: Escherichia coli. Organism_taxid: 562. Strain: k30. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F, G, H
(143 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of yersinia pestis yoph in complex with an aminooxy- containing platform compound for inhibitor design
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Structure of human dual-specificity phosphatase 27
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta2.
|
|
|
Chains:
A, B
(175 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of drosophila receptor protein tyrosine phosphatase dlar
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(196 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase sigma
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(197 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase sigma
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(200 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of chicken receptor protein tyrosine phosphatase sigma
|
|
|
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(203 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase lar
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(199 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase delta
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(195 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase delta
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(197 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-2 module of human receptor protein tyrosine phosphatase lar in complex with sucrose octasulphate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(198 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the n-terminal ig1-3 module of human receptor protein tyrosine phosphatase sigma
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(278 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of yoph in complex with 3-(1,1-dioxido-3- oxoisothiazolidin-5-yl)benzaldeyde
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the shp-1 c-terminal sh2 domain complexed with a tyrosine-phosphorylated peptide from nkg2a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: shp1. Other_details: cell-free protein synthesis. Synthetic: yes. Other_details: the human nkg2a phosphorylated peptide is chemicaly synthesized.
|
|
|
Chain:
A
(118 residues)
CATH domain:
|
|
|
|
|
|
New structure of cold-active protein tyrosine phosphatase at 1.1 angstrom
|
|
|
Source: Shewanella sp.. Organism_taxid: 50422. Gene: ppi. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(338 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of i115m mutant cold-active protein tyrosine phosphatase
|
|
|
Source: Shewanella sp.. Organism_taxid: 50422. Gene: ppi. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(331 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptp1b-inhibitor complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of ptp1b-inhibitor complexes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein-tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein-tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human tyrosine phosphatase shp2 (ptpn11) with an accessible active site
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(272 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of yoph complexed with pvsn and pvs, inhibitors of yoph which co-valent bind to cys of active site
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure yoph complexed with inhibitor pvs
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of yoph mutant d356a complexed with irreversible inhibitor pvsn
|
|
|
Source: Yersinia enterocolitica. Gene: yoph, yop51. Expressed in: escherichia coli.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase ptpn-22 (lyp) bound to the mono- phosphorylated lck active site peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized. The sequence of the peptide is naturally found in home sapiens(human).
|
|
|
Chains:
A, B
(296 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the ecdysone phosphate phosphatase, eppase, from bombix mori in complex with tungstate
|
|
|
Source: Bombyx mori. Silk moth. Organism_taxid: 7091. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(259 residues)
CATH domain:
|
|
|
|
|
|
High resolution crystal structure of the vaccinia virus dual- specificity phosphatase vh1
|
|
|
Source: Vaccinia virus. Strain: western reserve / wr. Gene: h1 orf. Expressed in: escherichia coli.
|
|
|
Chain:
A
(164 residues)
CATH domain:
|
|
|
|
|
|
Ptp1b in complex with a phosphonic acid inhibitor
|
|
|
Source: Homo sapiens. Human. Gene: ptpn1, ptp1b. Expressed in: escherichia coli.
|
|
|
Chain:
A
(285 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of heptp in complex with a monophosphorylated erk2 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of heptp in complex with a dually phosphorylated erk2 peptide mimetic
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence resembles that which occurs naturally in humans
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure ptp1b complex with aryl seleninic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure ptp1b complex with small molecule compound lzp-6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure ptp1b complex with small molecule inhibitor lzp-25
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of a leucine rich repeat and phosphatase domain containing protein from entamoeba histolytica
|
|
|
Source: Entamoeba histolytica. Strain: hm-1:imss. Gene: ehi_044170. Expressed in: escherichia coli.
|
|
|
Chain:
A
(144 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the s-nitrosylated cys215 of ptp1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human mkp-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp4, mkp2, vh2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D, E, F
(144 residues)
CATH domain:
|
|
|
|
|
|
Interaction of vhr with sa3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp3, vhr. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(179 residues)
CATH domain:
|
|
|
|
|
|
W354f yersinia enterocolitica ptpase apo form
|
|
|
Source: Yersinia enterocolitica (type o:9). Organism_taxid: 34055. Strain: w22703 / serotype o:9 / biotype 2. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
W354f yersinia enterocolitica ptpase complexed with tungstate
|
|
|
Source: Yersinia enterocolitica (type o:9). Organism_taxid: 34055. Strain: w22703 / serotype o:9 / biotype 2. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
W354f yersinia enterocolitica ptpase complexed with divanadate
|
|
|
Source: Yersinia enterocolitica (type o:9). Organism_taxid: 34055. Strain: w22703 / serotype o:9 / biotype 2. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of edeya2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(258 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(302 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Structure of edeya2 complexed with bef3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(259 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ed-eya2 complexed with alf3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(258 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of phosphotyrosine-binding domain from the human tensin-like c1 domain-containing phosphatase (tenc1)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa1075, tenc1, tns2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Modified pet26b
|
|
|
Chain:
A
(140 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of rat protein tyrosine phosphatase eta catalytic domain
|
|
|
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: ptprj. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(286 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b - transition state analog for the first catalytic step
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b, ptpn1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b - transition state analog for the second catalytic step
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b, ptpn1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Ca-like domain of human ptprz
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: htpzp2, ptprz, ptprz1, ptprz2, ptpz. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(268 residues)
CATH domain:
|
|
|
|
|
|
Ca-like domain of mouse ptprg
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(257 residues)
CATH domain:
|
|
|
|
|
|
Ca-like domain of human ptprg
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
C
(257 residues)
CATH domain:
|
|
|
|
|
|
Ptprg cntn4 complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cntn4. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Gene: ptprg. Expressed in: escherichia coli.
|
|
|
Chain:
B
(262 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mkp-4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(146 residues)
CATH domain:
|
|
|
|
|
|
Second pdz domain from human ptp1e
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F
(94 residues)
CATH domain:
|
|
|
|
|
|
Second pdz domain from human ptp1e in complex with ra-gef2 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rapgef6, pdzgef2
|
|
|
Chain:
A
(94 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of trypanosoma brucei protein tyrosine phosphatase tbptp1
|
|
|
Source: Trypanosoma brucei. Organism_taxid: 5691. Gene: tb10.70.0070. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(285 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
The 1.35 a structure of the phosphatase domain of the suppressor of t cell receptor signalling protein in complex with sulphate
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ubash3b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(264 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of shp2 in complex with a tautomycetin analog ttn d- 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(254 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the a isoform of human cytoplasmic protein tyrosine phosphatase (hcptp-a) in complex with 1-naphtylacetic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1, apc1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ptpn4 pdz domain complexed with thE C- terminus of a rabies virus g protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Rabies virus. Organism_taxid: 11292.
|
|
|
Chains:
A, B
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ptpn4 pdz domain complexed with thE C- terminus of the glun2a nmda receptor subunit
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: nr2a16 peptide has been chemically synthetized. The sequence ocuurs naturally in homo sapiens (human)
|
|
|
Chains:
A, B, C, D
(92 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of heptp with a closed wpd loop and an ordered e- loop
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(293 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of heptp with an open wpd loop and partially depleted active site
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of heptp with an atypically open wpd loop
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn7. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(276 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the oncogenic tyrosine phosphatase shp2 complexed with a salicylic acid-based small molecule inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chain:
A
(255 residues)
CATH domain:
|
|
|
|
|
|
Ptpn22 in complex with consensus phospho-tyrosine peptide 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence is derived from a peptide screen
|
|
|
Chains:
A, B, C, D
(297 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn22 in complex with skap-hom ptyr75 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chains:
A, B, C, D
(294 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of cell division cycle 25c protein isoform a from homo sapiens
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25c. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(167 residues)
CATH domain:
|
|
|
|
|
|
Solution structure of the pdz2 domain from human phosphatase hptp1e
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(96 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the full-length human protein tyrosine phosphatase shp-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn6, hcp, ptp1c. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(529 residues)
CATH domains:
|
|
|
|
|
|
Tandem ig domains of tyrosine phosphatase lar
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprf, lar. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(197 residues)
CATH domains:
|
|
|
|
|
|
Tandem ig repeats of dlar
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: lar, cg10443. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(199 residues)
CATH domains:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, apo
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(283 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with vanadate, orthorhombic crystal form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(283 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with vanadate, trigonal crystal form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via soaking
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(288 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(284 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2- carboxylic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(286 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]-n-(methylsulfonyl) thiophene-2-carboxamide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with n-[(3-aminophenyl)sulfonyl]-3-[(3,4-dichlorobenzyl) sulfanyl]thiophene-2-carboxamide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(285 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 5-[({3-[(3,4-dichlorobenzyl)sulfanyl]thiophen-2- yl}carbonyl)sulfamoyl]-2-methoxybenzoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(285 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]benzoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1- yl)benzoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-{[3-({n-[2- (methylamino)ethyl]glycyl}amino)phenyl]ethynyl}benzoic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(286 residues)
CATH domain:
|
|
|
|
|
|
Human receptor protein tyrosine phosphatase gamma, domain 1, trigonal crystal form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpg, ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(286 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b - apo w179f mutant with open wpd-loop
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b, ptpn1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(291 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b - w179f mutant bound with vanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b, ptpn1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(296 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of ywqe from bacillus subtilis and cpsb from streptococcus pneumoniae, unique metal-dependent tyrosine phosphatases
|
|
|
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: bsu36240, ywqe. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(247 residues)
CATH domain:
|
|
|
|
|
|
Crystal structures of ywqe from bacillus subtilis and cpsb from streptococcus pneumoniae, unique metal-dependent tyrosine phosphatases
|
|
|
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: bsu36240, ywqe. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(247 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structures of ywqe from bacillus subtilis and cpsb from streptococcus pneumoniae, unique metal-dependent tyrosine phosphatases
|
|
|
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Gene: cpsb, sp_0347, wzh. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(243 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the hd-ptp bro1 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(358 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpmt1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: plip, ptpmt1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpmt1 in complex with pi(5)p
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: plip, ptpmt1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(156 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex of the archaeal sulfolobus ptp-fold phosphatase with terpyridine platinum(ii)
|
|
|
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(159 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the s. Aureus protein tyrosine phosphatase ptpa
|
|
|
Source: Staphylococcus aureus. Organism_taxid: 1280. Gene: ptpa. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chain:
A
(158 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal of prl-1 complexed with peptide
|
|
|
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: norway rat, organism_taxid: 10116, prl1, ptp4a1. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes
|
|
|
Chains:
A, B
(152 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of ptp10d from drosophila melanogaster
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg1817, ptp10d. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of ptp10d from drosophila melanogaster with a small molecule inhibitor vanadate
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg1817, ptp10d. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of ptp10d from drosophila melanogaster with a phosphopeptide substrate gp4
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg1817, ptp10d. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of ptp10d from drosophila melanogaster with a small molecular inhibitor para-nitrocatechol sulphate
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg1817, ptp10d. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(287 residues)
CATH domain:
|
|
|
|
|
|
Crystal structrue of a novel mitogen-activated protein kinase phosphatase, skrp1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp19, dusp17, lmwdsp3, skrp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(144 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Protein tyrosine phosphatase (putative) from leishmania major
|
|
|
Source: Leishmania major. Organism_taxid: 5664. Strain: friedlin. Gene: lmjf16.0230, lmjf_16_0230. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(163 residues)
CATH domain:
|
|
|
|
|
|
Ptprz cntn1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: htpzp2, ptprz, ptprz1, ptprz2, ptpz. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cntn1. Expressed in: homo sapiens. Expression_system_taxid: 9606.
|
|
|
Chains:
A, B
(266 residues)
CATH domain:
|
|
|
|
|
|
Structure of ptp1b inactivated by h2o2/bicarbonate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp1b, ptpn1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mouse ptpsigma
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprs. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(568 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of p38alpha in complex with a mapk docking partner
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: mapk14, crk1, csbp1, csbp2. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
B
(130 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the mapk binding domain of mkp7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp16, kiaa1700, mkp7. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(128 residues)
CATH domain:
|
|
|
|
|
|
Structure of the shp-2 n-sh2 domain in a 1:2 complex with rvipyfvplnr peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was synthesized using standard fmoc/hbtu chemistry
|
|
|
Chain:
A
(100 residues)
CATH domain:
|
|
|
|
|
|
Structure of shp2 n-sh2 domain in complex with rlnpyaqlwhr peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: peptide was synthesized with standard fmoc.Hbtu chemistry
|
|
|
Chain:
A
(99 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of yophq357f(catalytic domain, residues 163-468) in complex with pncs
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yop51, yoph. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(282 residues)
CATH domain:
|
|
|
|
|
|
Catalytic domain of human shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: scs1 rosetta t1r.
|
|
|
Chain:
A
(261 residues)
CATH domain:
|
|
|
|
|
|
Catalytic domain of human shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: scs1 rosetta t1r.
|
|
|
Chain:
A
(259 residues)
CATH domain:
|
|
|
|
|
|
Catalytic domain of human shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: scs1 rosetta t1r.
|
|
|
Chain:
A
(263 residues)
CATH domain:
|
|
|
|
|
|
Catalytic domain of human shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: scs1 rosetta t1r.
|
|
|
Chain:
A
(267 residues)
CATH domain:
|
|
|
|
|
|
Src-derived peptide inhibitor complex of ptp1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(276 residues)
CATH domain:
|
|
|
|
|
|
Src-derived mutant peptide inhibitor complex of ptp1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(258 residues)
CATH domain:
|
|
|
|
|
|
Human protein-tyrosine phosphatase 1b c215a, s216a mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of human dusp26 (c152s)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril.
|
|
|
Chains:
A, B, C, D
(152 residues)
CATH domain:
|
|
|
|
|
|
Nitrate in the active site of ptp1b is a putative mimetic of the transition state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(285 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the murine aum (phosphoglycolate phosphatase) capping domain as a fusion protein with the catalytic core domain of murine chronophin (pyridoxal phosphate phosphatase)
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(304 residues)
CATH domains:
|
|
|
|
|
|
Structure of the catalytic domain of protein tyrosine phosphatase sigma in the sulfenic acid form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(567 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of point mutated dusp19 (c150a)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(147 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of point mutated dusp19 (r156a)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(141 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of point mutated dusp19 (i187a)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(140 residues)
CATH domain:
|
|
|
|
|
|
1.57 a crystal structure of erwinia amylovora tyrosine phosphatase amsi
|
|
|
Source: Erwinia amylovora. Organism_taxid: 716540. Strain: ea273. Atcc: atcc 49946. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(151 residues)
CATH domain:
|
|
|
|
|
|
The wild-type src homology 2 (sh2)-domain containing protein tyrosine phosphatase-2 (shp2)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(499 residues)
CATH domains:
|
|
|
|
|
|
Leopard syndrome-associated shp2/y279c mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(501 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of mbp-fused human six1 bound to human eya2 eya domain
|
|
|
Source: Escherichia coli, homo sapiens. Human. Organism_taxid: 562, 9606. Gene: b4034, jw3994, male, mbp, six1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Organism_taxid: 9606. Gene: eab1, eya2.
|
|
|
Chain:
B
(255 residues)
CATH domain:
|
|
|
|
|
|
Structure of vhz bound to metavanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp23, ldp3, vhz. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B
(150 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of yfkj from bacillus subtilis
|
|
|
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: yfkj, bsu07880. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(162 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase ptpn9 (meg2) complex with compound 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase ptpn9 (meg2) complex with compound 5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(298 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human protein tyrosine phosphatase ptpn9 (meg2) complex with compound 7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(303 residues)
CATH domain:
|
|
|
|
|
|
Structure of a sych-yoph chaperone-effector complex
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: sych, yp_pcd87, ypcd1.95c. Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51
|
|
|
Chain:
B
(28 residues)
|
|
|
|
|
|
Ptpn18 in complex with her2-py1248 phosphor-peptides
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn18, bdp1. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(268 residues)
CATH domain:
|
|
|
|
|
|
Ptpn18 in complex with her2-py1196 phosphor-peptides
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn18, bdp1. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(286 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of shp1 catalytic domain with so4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hcp, ptp1c, ptpn6, shp-1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(271 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of shp1 catalytic domain with po4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hcp, ptp1c, ptpn6, shp-1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of shp1 catalytic domain with jak1 activation loop peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hcp, ptp1c, ptpn6, shp-1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(279 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase shp-2 with y279c mutation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(497 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase shp-2 with d61g mutation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(496 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase shp-2 with q506p mutation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(486 residues)
CATH domains:
|
|
|
|
|
|
Shp-1 catalytic domain wpd loop open
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hcp, ptp1c, ptpn6, shp-1 (ptpn6). Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Shp-1 catalytic domain wpd loop closed
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hcp, ptp1c, ptpn6, shp-1 (ptpn6). Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(281 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Atomic structure of dusp26
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp24, dusp26, ldp4, mkp8, nata1, skrp3. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprn2, kiaa0387. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(88 residues)
CATH domain:
|
|
|
|
|
|
Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin at ph 4.6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprn2, kiaa0387. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(89 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase 1b in complex with an inhibitor [(4-{(2s)-2-(1,3-benzoxazol-2-yl)-2-[(4-fluorophenyl) sulfamoyl]ethyl}phenyl)amino](oxo)acetic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Her2 1221/1222 phosphorylation regulated by ptpn9
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans
|
|
|
Chain:
A
(292 residues)
CATH domain:
|
|
|
|
|
|
Cyrstal structure of protein tyrosine phosphatase lyp catalytic domain complex with small molecular inhibitor l75n04
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn22, ptpn8. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(302 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of monobody nsa1/shp2 n-sh2 domain complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(102 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of monobody cs1/shp2 c-sh2 domain complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(114 residues)
CATH domain:
|
|
|
|
|
|
Structure of dusp8
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp8, c11orf81, vh5. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(151 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of human dusp12
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp12. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(160 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of human dusp12 at 2.0 a resolution
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp12. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of a low molecular weight phosphotyrosine phosphatase from vibrio choleraeo395
|
|
|
Source: Vibrio cholerae. Organism_taxid: 345073. Strain: atcc 39541 / ogawa 395 / o395. Gene: vc0395_a0559, vc395_1055. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(148 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the 4th fn3 domain of human protein tyrosine phosphatase, receptor type f [psi-nysgrc-006240]
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lar, ptprf. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chain:
A
(108 residues)
CATH domain:
|
|
|
|
|
|
Structural basis of ptpn18 fingerprint on distinct her2 tyrosine phosphorylation sites
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn18, bdp1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, D, G
(283 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase shp-2 with n308d mutation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(489 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the tyrosine phosphatase shp-2 with e139d mutation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(498 residues)
CATH domains:
|
|
|
|
|
|
Structure of a ptp-like phytase from bdellovibrio bacteriovorus
|
|
|
Source: Bdellovibrio bacteriovorus. Organism_taxid: 264462. Strain: atcc 15356 / dsm 50701 / ncib 9529 / hd100. Gene: bd1204. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(261 residues)
CATH domain:
|
|
|
|
|
|
Leopard syndrome-associated shp2/a461t mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(494 residues)
CATH domains:
|
|
|
|
|
|
Leopard syndrome-associated shp2/g464a mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(489 residues)
CATH domains:
|
|
|
|
|
|
Leopard syndrome-associated shp2/q506p mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(494 residues)
CATH domains:
|
|
|
|
|
|
Leopard syndrome-associated shp2/q510e mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(502 residues)
CATH domains:
|
|
|
|
|
|
Leopard syndrome-associated shp2/t468m mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp2c, ptpn11, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(484 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with trkc
|
|
|
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: ntrk3, trkc. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293s. Gene: crypalpha1.
|
|
|
Chains:
C, D, E
(195 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with trkc
|
|
|
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: ntrk3, trkc. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293s. Gene: crypalpha1.
|
|
|
Chains:
D, E, F
(193 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the six n-terminal domains of human receptor protein tyrosine phosphatase sigma
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprs. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(568 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of protein tyrosine phosphatase shp2 catalytic domain complex with small molecular compound l88n79
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(264 residues)
CATH domain:
|
|
|
|
|
|
The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(299 residues)
CATH domain:
|
|
|
|
|
|
The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(299 residues)
CATH domain:
|
|
|
|
|
|
The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(299 residues)
CATH domain:
|
|
|
|
|
|
Shp2 sh2 domain in complex with gab1 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: this sequence occurs naturally in humans.
|
|
|
Chain:
A
(100 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn3 (ptph1) in complex with a dually phosphorylated mapk12 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(280 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group TPO
is 45.45% similar to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the ptpn3 (ptph1) catalytic domain c842s mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(283 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of p. Aeruginosa tpba
|
|
|
Source: Pseudomonas aeruginosa pao1. Organism_taxid: 208964. Gene: tpba, pa3885. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(162 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of p. Aeruginosa tpba (c132s) in complex with ptyr
|
|
|
Source: Pseudomonas aeruginosa pao1. Organism_taxid: 208964. Gene: tpba, pa3885. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(162 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Structure of human laforin dual specificity phosphatase domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: epm2a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C, D
(179 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human ptpdelta and human slitrk1 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprd. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: slitrk1, kiaa1910, lrrc12, unq233/pro266. Expression_system_taxid: 7108
|
|
|
Chain:
A
(300 residues)
CATH domains:
|
|
|
|
|
|
Co-crystal structure of shp2 in complex with a cefsulodin derivative
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(267 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn3 (ptph1) in complex with eps15 ptyr849 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic construct
|
|
|
Chain:
A
(280 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn3 (ptph1) h812f, m883g mutant in complex with eps15 ptyr849 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic construct
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn3 (ptph1) d811e, c842s mutant in complex with eps15 ptyr849 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic construct
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn3 (ptph1) y676i mutant in complex with vanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(283 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn3 (ptph1) d811e mutant in complex with metavanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(284 residues)
CATH domain:
|
|
|
|
|
|
Structure of a product bound phosphatase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: epm2a. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, C
(317 residues)
CATH domains:
Unassigned
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of ptpn3 (ptph1) in complex with eps15 ptyr849 p850v peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptph1, ptpn3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(279 residues)
CATH domain:
|
|
|
|
|
|
Structure of the cdc25b phosphatase catalytic domain with bound ligand
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(178 residues)
CATH domain:
|
|
|
|
|
|
Structure of the cdc25b phosphatase catalytic domain with bound inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc25b, cdc25hu2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(177 residues)
CATH domain:
|
|
|
|
|
|
Structure of of human dual-specificity phosphatase 22 (e24a/k28a/k30a/c88s) complexed with 4-nitrophenolphosphate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp22, jsp1, lmwdsp2, mkpx. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(158 residues)
CATH domain:
|
|
|
|
|
|
Structure of protein tyrosine phosphatase 1b complexed with inhibitor (ptp1b:cpt157633)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(293 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (c232s)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp7, pyst2. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B, C, D
(146 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the complex between slitrk2 lrr1 and ptp delta ig1-fn1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293f. Gene: slitrk2.
|
|
|
Chain:
A
(391 residues)
|
|
|
|
|
|
Yoph w354y yersinia enterocolitica ptpase apo form
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure ptp delta ig1-fn2 in complex with il-1racp
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: il1rap. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: freestyle 293-f. Gene: ptprd. Expression_system_cell_line: freestyle 293-f
|
|
|
Chain:
A
(491 residues)
|
|
|
|
|
|
Crystal structure of ptp delta fn1-fn2
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(193 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of ptp delta mea3/meb minus variant ig1-fn1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: freestyle 293-f
|
|
|
Chains:
B, A
(481 residues)
|
|
|
|
|
|
Crystal structure of ptpdelta ectodomain in complex with il1rapl1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: freestyle 293-f. Gene: il1rapl1. Expression_system_cell_line: freestyle 293-f
|
|
|
Chain:
A
(585 residues)
|
|
|
|
|
|
Crystal structure of jnk in complex with a regulator protein
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mapk8, jnk1, prkm8, sapk1, sapk1c. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: dusp16, kiaa1700, mkp7.
|
|
|
Chains:
G, B, D, H
(141 residues)
CATH domain:
|
|
|
|
|
|
Yoph w354h yersinia enterocolitica ptpase in the apo form
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Cell: yersinia pestis. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the apo low molecular weight protein tyrosine phosphatase isoform a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(164 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of low molecular weight protein tyrosine phosphatase isoform a complexed with phenylmethanesulfonic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of low molecular weight protein tyrosine phosphatase isoform a complexed with benzylphosphonic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Yoph w354h yersinia enterocolitica ptpase bond with divanadate glycerol ester in the active site
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Strain: dh5a. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Yoph w354y yersinia enterocolitica ptpase bond with divanadate glycerol ester in the active site
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Ptp1bc215s bound to nephrin peptide substrate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(297 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PTR
is 76.19% similar to
enzyme reactant [protein]-L-tyrosine phosphate
|
|
|
|
|
|
|
Crystal structure of human ptprz d1 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprz1, htpzp2, ptprz, ptprz2, ptpz. Expressed in: bombyx mori. Expression_system_taxid: 7091
|
|
|
Chain:
A
(283 residues)
CATH domain:
|
|
|
|
|
|
Cancer-associated shp2/t507k mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chain:
A
(498 residues)
|
|
|
|
|
|
Crystal structure of human phosphatase pten oxidized by h2o2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pten, mmac1, tep1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chains:
A, B, C, D
(314 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of prl-1 complex with compound analogy 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a1, prl1, ptpcaax1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(153 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human phosphatase pten treated with a bisperoxovanadium complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pten, mmac1, tep1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chains:
A, B, C, D
(314 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of human phosphatase pten in its reduced state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pten, mmac1, tep1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chains:
A, B, C, D
(314 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the bro domain of hd-ptp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(360 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the bro domain of hd-ptp in a complex with the core region of stam2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(357 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of ptpn11 tandem sh2 domains in complex with a txnip peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(212 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the complex between carbonic anhydrase-like domain of ptprg and immunoglobulin domains 2-3 of cntn3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprg, ptpg. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Mouse. Organism_taxid: 10090.
|
|
|
Chains:
A, C
(258 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex between carbonic anhydrase-like domain of ptprg and immunoglobulin domains 2-3 of cntn6
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprg. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cntn6.
|
|
|
Chains:
A, C
(264 residues)
CATH domain:
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp836
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(494 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp099
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(485 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the ptpn4 pdz domain complexed with the tailored peptide cyto8-retev
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: star. Synthetic: yes. Synthetic construct.
|
|
|
Chains:
A, B, C, D
(93 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the ptpn4 pdz domain complexed with the pdz binding motif of the mitogen activated protein kinase p38gamma.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(90 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human cd45 extracellular region, domains d1-d4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: t-cells. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell_line: cho-k1.
|
|
|
Chains:
A, B
(351 residues)
|
|
|
|
|
|
Crystal structure of human cd45 extracellular region, domains d1-d3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chain:
A
(252 residues)
|
|
|
|
|
|
Crystal structure of human cd45 extracellular region, domains d1-d2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: t-cells. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
|
|
|
Chains:
A, B
(172 residues)
|
|
|
|
|
|
Crystal structure of rat cd45 extracellular region, domains d3-d4
|
|
|
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: thymus. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell_line: cho-k1.
|
|
|
Chains:
A, B
(178 residues)
|
|
|
|
|
|
Crystal structure of pdz1 domain of human protein tyrosine phosphatase ptp-bas
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(96 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of sp-ptp, low molecular weight protein tyrosine phosphatase from streptococcus pyogenes
|
|
|
Source: Streptococcus pyogenes. Organism_taxid: 1314. Gene: ptpa. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(150 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of catalytically active form of human dusp26
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp26, dusp24, ldp4, mkp8, nata1, skrp3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: ril.
|
|
|
Chains:
A, B, C, D
(166 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Human ptprz d1 domain complexed with naz2329
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprz1, htpzp2, ptprz, ptprz2, ptpz. Expressed in: bombyx mori. Expression_system_taxid: 7091
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of ptpn12 catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn12. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(300 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Structure of f285s, a cancer-associated mutation of the oncogenic phosphatase shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(488 residues)
CATH domains:
|
|
|
|
|
|
Structure of s502p, a cancer-associated mutation of the oncogenic phosphatase shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(480 residues)
CATH domains:
|
|
|
|
|
|
Structure of e76q, a cancer-associated mutation of the oncogenic phosphatase shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(485 residues)
CATH domains:
|
|
|
|
|
|
Crystal structure of the catalytic domain of human protein tyrosine phosphatase non-receptor type 12 - k61r mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn12. Expressed in: escherichia coli. Expression_system_taxid: 511693.
|
|
|
Chains:
A, B, C, D
(296 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human low molecular weight protein tyrosine phosphatase (lmptp) type a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human low molecular weight protein tyrosine phosphatase (lmptp) type a complexed with phosphate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(152 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of human low molecular weight protein tyrosine phosphatase (lmptp) type a complexed with mes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of mouse low-molecular weight protein tyrosine phosphatase type a (lmptp-a) complexed with phosphate
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(153 residues)
CATH domain:
|
|
|
|
Bound ligand:
|
Het Group PO4
is 80.00% similar to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of bovine low molecular weight protein tyrosine phosphatase (lmptp) mutant (w49y n50e) complexed with hepes
|
|
|
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of bovine low molecular weight protein tyrosine phosphatase (lmptp) mutant (w49y n50e) complexed with vanadate and uncompetitive inhibitor
|
|
|
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex between human prl-2 phosphatase in reduced state and bateman domain of human cnnm3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a2, prl2, ptpcaax2, bm-008. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: cnnm3, acdp3.
|
|
|
Chain:
A
(156 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex between human phosphatase prl-2 in the oxidized state with the bateman domain of human magnesium transporter cnnm3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a2, prl2, ptpcaax2, bm-008. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: cnnm3, acdp3.
|
|
|
Chain:
A
(156 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the complex between phosphatase prl-2 in the oxidized state with the bateman domain of murine magnesium transporter cnnm3
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptp4a2, prl2. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: cnnm3, acdp3.
|
|
|
Chains:
A, B
(152 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of human phosphatase prl-2 in complex with the adp- bound bateman domain of human magnesium transporter cnnm3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a2, prl2, ptpcaax2, bm-008. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: cnnm3, acdp3.
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(279 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301) in complex with tcs401, closed state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b delta helix 7, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b delta helix 7 mutant in complex with tcs401, closed state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b yaya (y152a, y153a) mutant, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(280 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b yaya (y152a, y153a) mutant in complex with tcs401, closed state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(295 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b t178a mutant, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(280 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b t178a mutant in complex with tcs401, closed state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b l192a mutant, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(289 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b l192a mutant in complex with tcs401, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(299 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b delta helix 7, p185g mutant, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(281 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b delta helix 7, p185g mutant in complex with tcs401, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b p185g mutant, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(279 residues)
CATH domain:
|
|
|
|
|
|
Protein tyrosine phosphatase 1b n193a mutant in complex with tcs401, closed state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(285 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of lmw-ptp in complex with 2-(benzothiazol-2- ylamino)-2-oxo-1-phenylethanesulfonic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of lmw-ptp in complex with 2-oxo-1-phenyl-2- (phenylamino)ethanesulfonic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Co-crystal structure of lmw-ptp in complex with mes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(153 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of apo-form lmw-ptp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(154 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of hd-ptp phosphatase in complex with ubap1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(339 residues)
|
|
|
|
|
|
Crystal structure of hd-ptp phosphatase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(318 residues)
|
|
|
|
|
|
Structure of prl-1 in complex with the bateman domain of cnnm2
|
|
|
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ptp4a1, prl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cnnm2, acdp2. Expression_system_taxid: 562
|
|
|
Chains:
B, C
(151 residues)
CATH domain:
|
|
|
|
|
|
The molecular tweezer clr01 stabilizes a disordered protein-protein interface
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ywhaz. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
C
(19 residues)
|
|
|
|
|
|
The molecular tweezer clr01 stabilizes a disordered protein-protein interface
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ywhaz. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
C, D
(18 residues)
|
|
|
|
|
|
Crystal structure of yvh1 phosphatase domain from chaetomium thermophilum
|
|
|
Source: Chaetomium thermophilum var. Thermophilum dsm 1495. Organism_taxid: 759272. Gene: ctht_0021070. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(168 residues)
CATH domain:
|
|
|
|
|
|
Crystal structure of the his domain protein tyrosine phosphatase (hd- ptp/ptpn23) bro1 domain (sara complex structure)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(358 residues)
|
|
|
|
|
|
Crystal structure of the his domain protein tyrosine phosphatase (hd- ptp/ptpn23) bro1 domain (apo structure)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(361 residues)
|
|
|
|
|
|
Crystal structure of the his domain protein tyrosine phosphatase (hd- ptp/ptpn23) bro1 domain (endofin peptide complex)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, C
(361 residues)
|
|
|
|
|
|
Crystal structure of the his domain protein tyrosine phosphatase (hd- ptp/ptpn23) bro1 domain (chmp4a peptide complex structure)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(358 residues)
|
|
|
|
|
|
Crystal structure of the his domain protein tyrosine phosphatase (hd- ptp/ptpn23) bro1 domain (chmp4b peptide complex structure)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(355 residues)
|
|
|
|
|
|
Crystal structure of the his domain protein tyrosine phosphatase (hd- ptp/ptpn23) bro 1 domain (chmp4c peptide complex structure)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn23, kiaa1471. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C, D
(361 residues)
|
|
|
|
|
|
Structure of prl-1 in complex with the bateman domain of cnnm2
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cnnm2, acdp2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ptp4a1, prl1. Expression_system_taxid: 562
|
|
|
Chain:
B
(150 residues)
CATH domain:
|
|
|
|
|
|
P130cas sh3 domain ptp-pest peptide chimera
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcar1, ptpn12. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(100 residues)
|
|
|
|
|
|
Crystal structure of the slr0328 tyrosine phosphatase wzb from synechocystis sp. Pcc 6803
|
|
|
Source: Synechocystis sp. (Strain pcc 6803 / kazusa). Organism_taxid: 1111708. Strain: pcc 6803 / kazusa. Gene: slr0328. Expressed in: escherichia coli. Expression_system_taxid: 1007065. Expression_system_variant: prep4.
|
|
|
Chain:
A
(105 residues)
|
|
|
|
|
|
X-ray characterization of striatal-enriched protein tyrosine phosphatase inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(287 residues)
|
|
|
|
|
|
X-ray characterization of striatal-enriched protein tyrosine phosphatase inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(287 residues)
|
|
|
|
|
|
X-ray characterization of striatal-enriched protein tyrosine phosphatase inhibitors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytosol. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(157 residues)
CATH domain:
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000740a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000295a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000294a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000004a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000157a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000211a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000069a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000072a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000074a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000163a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmocr000171b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000207a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000847b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000089a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000108a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000475a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000466a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000574a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000465a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000484a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000599c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000435a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000648a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(294 residues)
|
|
|
|
Bound ligand:
|
Het Group JGS
is 47.83% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000645a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000398a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000449a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000514a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000632a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000608a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000601a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000127a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000232a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000733a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000639a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000270a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000538a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000240a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(293 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000134a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000278a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000323a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_pktta024495b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa001247b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmoze000092b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000675b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(292 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000217b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000955b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000657b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000692b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000245b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000847b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(299 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000141a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000017a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
Bound ligand:
|
Het Group DSJ
is 55.56% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000149a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000603b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000470b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000123a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000708a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000713b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000216b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
Bound ligand:
|
Het Group JMG
is 40.91% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000272b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000187a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000194a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000144a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa001440b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000281b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000951b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000114a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000242a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000752b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_pkooa000283c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000140a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000505a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000509a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000515a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000523a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000525a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000531a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
Bound ligand:
|
Het Group JOG
is 48.00% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000814b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000509a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000206a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000269a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000324a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000644b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000293a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000491a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000497a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
Bound ligand:
|
Het Group JKA
is 45.45% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmomb000293a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000683b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000487a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000491a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000497a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
Bound ligand:
|
Het Group JKA
is 45.45% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000953b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000396a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000711a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_xst00000280c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000619a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000275a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000662a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000666a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
Bound ligand:
|
Het Group JPD
is 61.90% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa000811b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmsoa001176b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000611a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000555a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000595a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000540a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000628a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000650a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000611a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmopl000619a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with compound_fmooa000539a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(285 residues)
|
|
|
|
|
|
Structure of ptp1b complexed with n-(3'-(1,1-dioxido-4-oxo-1,2,5- thiadiazolidin-2-yl)-4'-methyl-[1,1'-biphenyl]-4-yl)acetamide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(300 residues)
|
|
|
|
|
|
Crystal structure of prl-3 phosphatase in complex with the bateman domain of cnnm3 magnesium transporter
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a3, prl3. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: cnnm3, acdp3.
|
|
|
Chains:
A, C
(155 residues)
|
|
|
|
|
|
Rhizobiales-like phosphatase 2
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: t22k18.22, at3g09970. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Arabidopsis thaliana rhizobiales-like phosphatase 2 complexed with tungstate
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: t22k18.22, at3g09970. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Structure of human sts-1 histidine phosphatase domain with sulfate bound
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubash3b, kiaa1959, sts1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(264 residues)
|
|
|
|
|
|
Structure of human sts-1 histidine phosphatase domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubash3b, kiaa1959, sts1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(262 residues)
|
|
|
|
|
|
Crystal structure of ptp delta ig1-ig3 in complex with il1rapl1 ig1- ig3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprd. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: il1rapl1, ophn4.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Crystal structure of shp2_sh2-caga epiya_c peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Helicobacter pylori. Organism_taxid: 210
|
|
|
Chain:
A
(206 residues)
|
|
|
|
|
|
Crystal structure of shp2_sh2-caga epiya_d peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Synthetic: yes. Helicobacter pylori. Organism_taxid: 102608
|
|
|
Chains:
A, B
(206 residues)
|
|
|
|
|
|
Two intermediate states of conformation switch in dual specificity phosphatase 13a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp13, bedp, dusp13a, mdsp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(170 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structures of human salm5 in complex with human ptpdelta
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: lrfn5, c14orf146, salm5. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: ptprd. Expression_system_taxid: 9606
|
|
|
Chains:
D, E
(291 residues)
|
|
|
|
|
|
Crystal structure of budding yeast cdc14p (wild type) in the apo state
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: cdc14, oaf3, yfr028c. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(368 residues)
|
|
|
|
|
|
Crystal structure of budding yeast cdc14p (c283s) bound to a swi6p phosphopeptide
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: cdc14, oaf3, yfr028c. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes.
|
|
|
Chains:
A, B
(362 residues)
|
|
|
|
Bound ligand:
|
Het Group SEP
is 50.00% similar to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of ptpdelta ig1-fn1 in complex with salm5 lrr-ig
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: homo sapiens. Expression_system_taxid: 9606. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chains:
A, C
(382 residues)
|
|
|
|
|
|
Crystal structure of ptpdelta ig1-ig3 in complex with salm2 lrr-ig
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: lrfn1, salm2, semo1. Expression_system_taxid: 9606
|
|
|
Chains:
A, C
(293 residues)
|
|
|
|
Bound ligand:
|
Het Group NAG
is 47.62% similar to
enzyme product [protein]-L-tyrosine
|
|
|
|
|
|
|
The atomic structure of shp2 e76a mutant in complex with allosteric inhibitor 9b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(519 residues)
|
|
|
|
|
|
Crystal structure of human dusp28
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp28. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(148 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of human dusp28(y102h)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp28. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(148 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of ptp delta ig1-ig2 in complex with il1rapl1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: il1rapl1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: ptprd. Expression_system_taxid: 9606
|
|
|
Chain:
A
(209 residues)
|
|
|
|
|
|
Crystal structure of low molecular weight phosphotyrosine phosphatase (vclmwptp-2) from vibrio choleraeo395
|
|
|
Source: Vibrio cholerae serotype o1 (strain atcc 39541 / classical ogawa 395 / o395). Organism_taxid: 345073. Strain: atcc 39541 / classical ogawa 395 / o395. Gene: vc0395_a0440. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(153 residues)
|
|
|
|
|
|
Structural basis for an allosteric eya2 phosphatase inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: eya2, eab1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A, C
(253 residues)
|
|
|
|
|
|
Crystal structure of human dual specificity phosphatase 1 catalytic domain (c258s) as a maltose binding protein fusion in complex with the monobody ysx1
|
|
|
Source: Escherichia coli (strain k12), homo sapiens. Human. Organism_taxid: 83333, 9606. Strain: k12. Gene: male, b4034, jw3994, dusp1, cl100, mkp1, ptpn10, vh1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chain:
A
(510 residues)
|
|
|
|
|
|
Oxidized shp2 forms a disulfide bond between cys367 and cys459
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(496 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Multiconformer model of apo wt ptp1b with glycerol at 180 k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Multiconformer model of apo wt ptp1b with glycerol at 240 k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(299 residues)
|
|
|
|
|
|
Multiconformer model of apo wt ptp1b with glycerol at 278 k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Multiconformer model of wt ptp1b with bb3 at 273 k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(286 residues)
|
|
|
|
|
|
Multiconformer model of apo wt ptp1b with glycerol at 100 k (alternative refinement of PDB 1sug showing conformational heterogeneity)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Multiconformer model of k197c ptp1b tethered to compound 2 at 100 k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(285 residues)
|
|
|
|
Bound ligand:
|
Het Group D0P
is 46.43% similar to
enzyme reactant [protein]-L-tyrosine phosphate
|
|
|
|
|
|
|
Multiconformer model of apo k197c ptp1b at 100 k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp244
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(489 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitors shp099 and shp244
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(480 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp504
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(483 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitors shp099 and shp504
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(475 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp844
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(488 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitors shp099 and shp844
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(480 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 f285s in complex with allosteric inhibitor jlr-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(448 residues)
|
|
|
|
|
|
Closed structure of inactive shp2 mutant c459e
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(498 residues)
|
|
|
|
|
|
Structure of human shp2 without n-sh2 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(400 residues)
|
|
|
|
|
|
Closed structure of active shp2 mutant e76d bound to shp099 inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(494 residues)
|
|
|
|
|
|
Closed structure of active shp2 mutant e76k bound to shp099 inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Variant: e76k. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chain:
A
(497 residues)
|
|
|
|
|
|
Crystal structure of shp2 e76k gof mutant in the open conformation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(475 residues)
|
|
|
|
|
|
Crystal structure of shp2 e76k gof mutant in complex with shp099
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(477 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b f135y mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b a122s mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Crystal structure of the ptp epsilon d2 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpre. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(275 residues)
|
|
|
|
|
|
Crystal structure of the ptp epsilon d1 domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpre. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(283 residues)
|
|
|
|
|
|
Crystal structure of ptp epsilon d2 domain (a455n/v457y/e597d)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpre. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(269 residues)
|
|
|
|
|
|
Crystal structure of the human dual specificity phosphatase 1 catalytic domain (c258s) as a maltose binding protein fusion in complex with the designed ar protein off7
|
|
|
Source: Escherichia coli (strain k12), homo sapiens. Human. Organism_taxid: 83333, 9606. Strain: k12. Gene: male, b4034, jw3994, dusp1, cl100, mkp1, ptpn10, vh1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chains:
A, C
(511 residues)
|
|
|
|
|
|
Crystal structure of the human dual specificity 1 catalytic domain (c258s) as a maltose binding protein fusion in complex with the designed ar protein mbp3_16
|
|
|
Source: Escherichia coli (strain k12), homo sapiens. Human. Organism_taxid: 83333, 9606. Strain: k12. Gene: male, b4034, jw3994, dusp1, cl100, mkp1, ptpn10, vh1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chain:
A
(517 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the human dual specificity phosphatase 1 catalytic domain (c258s) as a maltose binding protein fusion (maltose bound form) in complex with the designed ar protein mbp3_16
|
|
|
Source: Escherichia coli (strain k12), homo sapiens. Human. Organism_taxid: 83333, 9606. Strain: k12. Gene: male, b4034, jw3994, dusp1, cl100, mkp1, ptpn10, vh1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic construct. Organism_taxid: 32630.
|
|
|
Chain:
A
(514 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Yoph ptp1b chimera 2 ptpase
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph, ypcd1.67c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Yoph ptp1b wpd loop chimera 2 ptpase bound to vanadate
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph, ypcd1.67c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of the yoph ptp1b chimera 3 ptpase apo form
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph, ypcd1.67c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(278 residues)
|
|
|
|
|
|
Crystal structure of the yoph ptp1b wpd loop chimera 3 ptpase bound to tungstate
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph, ypcd1.67c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(278 residues)
|
|
|
|
|
|
Crystal structure of the yoph ptp1b chimera 3 ptpase bound to vanadate
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph, ypcd1.67c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Structure of cdc14 bound to cbk1 pxl motif
|
|
|
Source: Saccharomyces cerevisiae (strain atcc 204508 / s288c). Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: cdc14, oaf3, yfr028c. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: plyss.
|
|
|
Chains:
A, B
(356 residues)
|
|
|
|
|
|
Structure of cdc14 bound to cbk1 pxl motif
|
|
|
Source: Saccharomyces cerevisiae s288c. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: cdc14, oaf3, yfr028c. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: plyss. Synthetic: yes.
|
|
|
Chains:
A, B
(361 residues)
|
|
|
|
|
|
Structure of cdc14 bound to sic1 pxl motif
|
|
|
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: cdc14, oaf3, yfr028c. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 4932
|
|
|
Chains:
A, B
(357 residues)
|
|
|
|
|
|
Murine protein tyrosine phosphatase ptpn13 pdz3 domain
|
|
|
Source: Mus musculus. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(119 residues)
|
|
|
|
|
|
Murine protein tyrosine phosphatase ptpn13 pdz3 domain-prk2 peptide complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptpn13, ptp14. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human.
|
|
|
Chain:
A
(119 residues)
|
|
|
|
|
|
Crystal structure of the human protein tyrosine phosphatase ptpn5 (step) in complex with compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(288 residues)
|
|
|
|
|
|
Crystal structure of the mouse protein tyrosine phosphatase ptpn5 (step) in complex with compound bi-0314
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptpn5. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(291 residues)
|
|
|
|
|
|
Crystal structure of the ptpn3 pdz domain bound to the hpv16 e6 oncoprotein c-terminal peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn3, ptph1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Human papillomavirus type 16. Organism_taxid: 333760. Gene: e6.
|
|
|
Chains:
A, B, C, D, E, F
(93 residues)
|
|
|
|
|
|
The ptp domain of human ptpn14 in a complex with the cr3 domain of hpv18 e7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn14. Expressed in: escherichia coli. Expression_system_taxid: 562. Human papillomavirus type 18. Organism_taxid: 333761. Gene: e7.
|
|
|
Chain:
A
(289 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Rat ptprz d1-d2 domain
|
|
|
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: ptprz1, ptprz, ptpz. Expressed in: bombyx mori. Expression_system_taxid: 7091
|
|
|
Chains:
A, B
(534 residues)
|
|
|
|
|
|
Crystal structure of kibra and ptpn14 complex
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: wwc1, kiaa0869. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
|
|
|
Chain:
U
(20 residues)
|
|
|
|
|
|
Crystal structure of ptprd phosphatase domain in complex with liprin- alpha3 tandem sam domains
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta. Gene: ppfia3. Expression_system_variant: rosetta
|
|
|
Chain:
A
(293 residues)
|
|
|
|
|
|
Crystal structure of the liprin-alpha3_sam123/lar_d1d2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf, lar. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Mus musculus. Mouse. Organism_taxid: 10090.
|
|
|
Chains:
A, B, C, D
(575 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of atptp1 at 1.4 angstrom
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: ptp1, at1g71860, f14o23.24. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Crystal structure of atptp1 at 1.7 angstrom
|
|
|
Source: Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: ptp1, at1g71860, f14o23.24. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333
|
|
|
Chain:
A
(302 residues)
|
|
|
|
|
|
Structure of ptp-meg2 and nsf-py83 peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(296 residues)
|
|
|
|
|
|
Structure of ptp-meg2 and munc18-1-py145 peptide complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn9. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Crystal structure of dusp22 mutant_c88s
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp22, jsp1, lmwdsp2, mkpx. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(157 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of dusp22 mutant_c88s/s93a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp22, jsp1, lmwdsp2, mkpx. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(156 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of dusp22 mutant_n128d
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp22, jsp1, lmwdsp2, mkpx. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(151 residues)
|
|
|
|
|
|
Crystal structure of dusp22 mutant_c88s/s93n
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp22, jsp1, lmwdsp2, mkpx. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(156 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of dusp22_vo4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp22, jsp1, lmwdsp2, mkpx. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(157 residues)
|
|
|
|
|
|
Structure of map kinase phosphatase 5 in complex with 3,3-dimethyl-1- ((9-(methylthio)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan- 2-one, an allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D, E, F
(147 residues)
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor pyrimidinone 7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(496 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor isoxazolo-pyridinone 3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(468 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor pyrazolo-pyridine 4
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(468 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor pyrazolo-pyrimidinone 5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(487 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor pyrazolo-pyrimidinone 1 shp389
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(483 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor imidazo-pyridine 24
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(477 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Ptp1b domain of ptp1b-lov2 chimera
|
|
|
Source: Homo sapiens, avena sativa. Human, oat. Organism_taxid: 9606, 4498. Gene: ptpn1, ptp1b, nph1-1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), f182a mutant, apo state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(296 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), p188a mutant, apo state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), p185a mutant, apo state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), p180a mutant, apo state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), t177a mutant, apo state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), p188a mutant, vanadate bound state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), t177a mutant, vanadate bound state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), f182a mutant, vanadate bound state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), p185a mutant, vanadate bound state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b (1-301), p180a mutant, vanadate bound state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
C-sh2 domain of shp-2 in complex with phospho-itsm of pd-1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(119 residues)
|
|
|
|
|
|
Structure of the n-sh2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, B
(102 residues)
|
|
|
|
|
|
Structure of the n-sh2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based switch motif
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
|
|
|
Chains:
A, C
(102 residues)
|
|
|
|
|
|
Mbc/shp1-c-sh2 complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn6, hcp, ptp1c. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic construct. Organism_taxid: 32630. Expression_system_taxid: 511693
|
|
|
Chain:
A
(106 residues)
|
|
|
|
|
|
Human ptpru d1 domain, reduced form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpru, fmi, pcp2, ptpro. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
|
|
|
Chain:
A
(253 residues)
|
|
|
|
|
|
Human ptpru d1 domain, oxidised form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpru, fmi, pcp2, ptpro. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: rosetta.
|
|
|
Chain:
A
(240 residues)
|
|
|
|
|
|
Crystal structure of the ptpn3 pdz domain bound to the hbv core protein c-terminal peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn3, ptph1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Hepatitis b virus. Hbv.
|
|
|
Chain:
A
(93 residues)
|
|
|
|
|
|
Crystal structures of fniii domain three and four of the human leucocyte common antigen-related protein, lar
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf, lar. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(194 residues)
|
|
|
|
|
|
Crystal structures of fniii domain three and four of the human leucocyte common antigen-related protein, lar
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf, lar. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(194 residues)
|
|
|
|
|
|
Crystal structures of fniii domain one and two of the human leucocyte common antigen-related protein, lar
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf, lar. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(191 residues)
|
|
|
|
|
|
Crystal structures of fniii domain one through four of the human leucocyte common antigen-related protein ( lar)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprf, lar. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(375 residues)
|
|
|
|
|
|
Crystal structure of vpsu (vc0916) from vibrio cholerae
|
|
|
Source: Vibrio cholerae. Organism_taxid: 666. Gene: etp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(149 residues)
|
|
|
|
|
|
Crystal structure of rptp alpha
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpra, ptpa, ptprl2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(587 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b bound to amorphadiene
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chain:
A
(287 residues)
|
|
|
|
|
|
Structure of human shp2 in complex with inhibitor iacs-13909
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(494 residues)
|
|
|
|
|
|
Crystal structure of prl-2 phosphatase c101d mutant in complex with the bateman domain of cnnm3 magnesium transporter
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a2, prl2, ptpcaax2, bm-008. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cnnm3, acdp3.
|
|
|
Chain:
A
(158 residues)
|
|
|
|
|
|
Crystal structure of prl-1 phosphatase c104d mutant in complex with the bateman domain of cnnm2 magnesium transporter
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cnnm2, acdp2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ptp4a1, prl1.
|
|
|
Chain:
B
(151 residues)
|
|
|
|
|
|
Crystal structure of the fn5 domain of drosophila lar
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: lar, cg10443. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(93 residues)
|
|
|
|
|
|
Crystal structure of the fn5 domain of mouse lar
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprf, lar. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(100 residues)
|
|
|
|
|
|
Crystal structure of the fn4-fn6 domains of human ptprd
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprd. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(306 residues)
|
|
|
|
|
|
Crystal structure of the ptp1b yoph wpd loop chimera 3 apo form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(296 residues)
|
|
|
|
|
|
Crystal structure of the ptp1b yoph wpd loop chimera 3 bound to vanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(299 residues)
|
|
|
|
|
|
Crystal structure of the ptp1b yoph wpd loop chimera 3 bound to tungstate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Crystal structure of the ptp1b yoph wpd loop chimera 4 apo form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(291 residues)
|
|
|
|
|
|
Crystal structure of the ptp1b yoph wpd loop chimera 4 bound to vanadate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Crystal structure of the ptp1b yoph wpd loop chimera 4 bound to tungstate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Crystal structure of the cys-no modified yoph tyrosine phosphatase
|
|
|
Source: Yersinia enterocolitica. Organism_taxid: 630. Gene: yoph, yop51. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of the double mutant l13r i16k of low molecular weight protein tyrosine phosphatase (lmw-ptp)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(153 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the single mutant i16k of low molecular weight protein tyrosine phosphatase (lmw-ptp)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(153 residues)
|
|
|
|
|
|
Crystal structure of the ptpn2 c216g mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(279 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of the f-bar domain of pstipip1 bound to the cth domain of the phosphatase lyp
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pstpip1, cd2bp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
C
(14 residues)
|
|
|
|
|
|
Crystal structure of dusp22 mutant_n128a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp22, jsp1, lmwdsp2, mkpx. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(156 residues)
|
|
|
|
|
|
Crystal structure of the complex between mouse ptp delta and neuroligin-3
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: ptprd. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293f. Cell_line: hek293f. Gene: nlgn3.
|
|
|
Chain:
A
(386 residues)
|
|
|
|
|
|
Crystal structure of primo-1
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: primo-1, cg31311. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(154 residues)
|
|
|
|
|
|
Vibrio vulnificus wzb
|
|
|
Source: Vibrio vulnificus. Organism_taxid: 672. Gene: wzb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c43.
|
|
|
Chains:
A, B
(148 residues)
|
|
|
|
|
|
Vibrio vulnificus wzb in complex with benzylphosphonate
|
|
|
Source: Vibrio vulnificus. Organism_taxid: 672. Gene: wzb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c43.
|
|
|
Chains:
A, B, C, D
(146 residues)
|
|
|
|
|
|
Vibrio vulnificus wzb in complex with benzylphosphonate
|
|
|
Source: Vibrio vulnificus. Organism_taxid: 672. Gene: wzb. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: c43.
|
|
|
Chains:
A, B, C, D
(146 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
The atomic structure of shp2 e76a mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(493 residues)
|
|
|
|
|
|
Crystal structure of cnyvh1 complex with vanadate
|
|
|
Source: Cryptococcus neoformans var. Grubii serotype a (strain h99 / atcc 208821 / cbs 10515 / fgsc 9487). Filobasidiella neoformans var. Grubii. Organism_taxid: 235443. Strain: h99 / atcc 208821 / cbs 10515 / fgsc 9487. Gene: cnag_01203. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(175 residues)
|
|
|
|
|
|
Crystal structure of tcptp catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(296 residues)
|
|
|
|
|
|
Crystal structure of ptpn2 catalytic domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(293 residues)
|
|
|
|
|
|
Structure-activity relationship studies of allosteric inhibitors of eya2 tyrosine phosphatase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: eya2, eab1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(259 residues)
|
|
|
|
|
|
Structure-activity relationship studies of allosteric inhibitors of eya2 tyrosine phosphatase
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: eya2, eab1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A, C
(257 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000619a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmooa000497a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmooa000523a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmooa000505a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmooa000611a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmooa000666a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmooa000555a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmomb000293a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmsoa000470b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000847b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmocr000171b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000601a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000278a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmomb000203a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b after initial refinement with no ligand modeled
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000089a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z31222641
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z2856434762
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z321318226
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z2856434770
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z30820160
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z2856434917
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z509756472
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z915492990
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z744754722
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000245b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000217b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with z2856434906
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000621a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000466a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000631a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000729a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000605a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000383a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000421a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000316a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000530a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000046b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000543a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000279a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000519b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmomb000149a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000382a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmsoa001440b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmsoa000686b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(280 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000752b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmsoa001439b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmsoa000899b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00001145b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000754b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000280c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000688a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(297 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000311a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000587a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmopl000604a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with fmomb000297a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition -- crystal structure of ptp1b in complex with xst00000765c
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster3
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster5
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster8
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster9
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster11
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster12
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster14
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster15
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster16
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster17
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster18
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster19
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Pandda analysis group deposition of ground-state model of ptp1b, using pre-clustering, cluster20
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
The structural basis of pten regulation by multi-site phosphorylation
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Crystal structure of pten with a tetra-phosphorylated tail (4p-crpten- 13sp-t2, sdttdsdpeneg)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pten, mmac1, tep1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chain:
A
(313 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of non phosphorylated pten (n-crpten-13sp-t1, sdttdsdpeneg)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pten, mmac1, tep1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111
|
|
|
Chain:
A
(315 residues)
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor tno155
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(486 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor compound 24
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chains:
A, B
(476 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of pten (aa 7-353 followed by spacer tgggsggtgggsggtgggcy ligated to peptide psdptptdpsdpenepfded)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pten, mmac1, tep1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
|
|
|
Chain:
A
(314 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Protein tyrosine phosphatase 1b, d289a mutant, apo state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b, apo
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Human lmptp in complex with inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(155 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b with inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(278 residues)
|
|
|
|
|
|
Ligand-free ptp1b t177g
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(299 residues)
|
|
|
|
|
|
Vanadate-bound ptp1b t177g
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Ligand-free yoph g352t
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph, y0013, ypcd1.67c, g4d65_20050, g4d67_19670, gd372_22270. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Vanadate-bound yoph g352t
|
|
|
Source: Yersinia pestis. Organism_taxid: 632. Gene: yoph, y0013, ypcd1.67c, g4d65_20050, g4d67_19670, gd372_22270. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Ptp1b f225y mutant, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(280 residues)
|
|
|
|
|
|
Ptp1b in complex with tcs401 by native s-sad at room temperature
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Ptp1b f225y in complex with tcs401
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(300 residues)
|
|
|
|
|
|
Ptp1b 1-284 f225y-r199n
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(280 residues)
|
|
|
|
|
|
Ptp1b 1-284 f225y-r199n in complex with tcs401
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Ptp1b f225y-r199n-l195r in complex with tcs401
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Ptp1b l204a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(278 residues)
|
|
|
|
|
|
Ptp1b l204a in complex with tcs401
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(299 residues)
|
|
|
|
|
|
Ptp1b p206g mutation, open state
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Ptp1b p206g in complex with tcs401
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Ptp1b f225y-r199n-l195r
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Ptp1b 1-301 f225y-r199n mutations
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(280 residues)
|
|
|
|
|
|
Ptp1b f225i in complex with tcs401
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(300 residues)
|
|
|
|
|
|
Phosphoglycolate phosphatase from mus musculus
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: pgp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F, G, H
(302 residues)
|
|
|
|
|
|
Phosphoglycolate phosphatase with inhibitor cp1
|
|
|
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: pgp. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(311 residues)
|
|
|
|
|
|
Shp2 catalytic domain in complex with irs1 (625-639) phosphopeptide (ptyr-632, pser-636)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Shp2 catalytic domain in complex with irs1 (889-901) phosphopeptide (pser-892, ptyr-896)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(277 residues)
|
|
|
|
|
|
Shp2 catalytic domain in complex with cd28 (183-198) phosphopeptide (ptyr-191, p-thr-195)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Two-state liquid nmr structure of a pdz2 domain from hptp1e, apo form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chain:
A
(96 residues)
|
|
|
|
|
|
Two-state liquid nmr structure of a pdz2 domain from hptp1e, complexed with ra-gef2 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chain:
A
(96 residues)
|
|
|
|
|
|
Structure of human shp2 in complex with compound 16
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(494 residues)
|
|
|
|
|
|
Structure of human shp2 in complex with compound 22
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(489 residues)
|
|
|
|
|
|
Structure of human shp2 in complex with compound 27
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(489 residues)
|
|
|
|
|
|
Structure of human shp2 in complex with compound 30
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(490 residues)
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor rmc-4550
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
B, A
(501 residues)
|
|
|
|
|
|
Apo ptp1b by native s-sad at room temperature
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Protein tyrosine phosphatase 1b - f182q mutant bound with hepes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Structure of the ptp-like myo-inositol phosphatase from legionella pneumophila str. Paris in complex with myo-inositol-(1,3,4,5)- tetrakisphosphate
|
|
|
Source: Legionella pneumophila str. Paris. Organism_taxid: 297246. Gene: hopd2, nctc12000_03020. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(288 residues)
|
|
|
|
|
|
Crystal structure of monobody mb(shp2ptp_13)/shp2 ptp domain complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic construct. Organism_taxid: 32630. Expression_system_taxid: 562
|
|
|
Chains:
A, D
(270 residues)
|
|
|
|
|
|
Structure of cd148 fibronectin type iii domain 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprj, dep1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(105 residues)
|
|
|
|
|
|
Structure of cd148 fibronectin type iii domain 1 and 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprj, dep1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(193 residues)
|
|
|
|
|
|
Structure of map kinase phosphatase 5 in complex with 3,3-dimethyl-1- ((9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(150 residues)
|
|
|
|
|
|
Structure of map kinase phosphatase 5 in complex with 3,3-dimethyl-1- ((9-propyl-5,6-dihydrothieno[2,3-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(147 residues)
|
|
|
|
|
|
Crystal structure of human ptpn2 with inhibitor abbv-cls-484
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(277 residues)
|
|
|
|
|
|
Structure of map kinase phosphatase 5 in complex with 3,3-dimethyl-1- ((5,6-dihydrobenzo[h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(149 residues)
|
|
|
|
|
|
Structure of map kinase phosphatase 5 in complex with 3,3-dimethyl-1- ((5,6-dihydropyrido[2,3-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(150 residues)
|
|
|
|
|
|
Structure of map kinase phosphatase 5 in complex with 3,3-dimethyl-1- ((9-chloro-5,6-dihydrobenzo[h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(148 residues)
|
|
|
|
|
|
Structure of map kinase phosphatase 5 in complex with 3,3-dimethyl-1- ((9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(150 residues)
|
|
|
|
|
|
The co-crystal structure of low molecular weight protein tyrosine phosphatase (lmw-ptp) with a small molecule inhibitor spaa-2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(154 residues)
|
|
|
|
|
|
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor tk-453
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D
(477 residues)
|
|
|
|
|
|
Crystal structure of ptpn4 pdz bound to the pbm of hpv16 e6
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn4. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Human papillomavirus type 16. Organism_taxid: 333760
|
|
|
Chains:
A, B, C, D
(89 residues)
|
|
|
|
|
|
Crystal structure of human rptph
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprh, sap1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(287 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Small-molecule allosteric regulation mechanism of shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(473 residues)
|
|
|
|
|
|
Crystal structure of the second pdz domain from human ptpn13 in complex with apc peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn13, pnp1, ptp1e, ptpl1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(89 residues)
|
|
|
|
|
|
Crystal structure of dusp10 mutant_d59a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B
(149 residues)
|
|
|
|
|
|
Crystal structure of dusp10
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B, C, D
(149 residues)
|
|
|
|
|
|
Crystal structure of dusp10 mutant_s95a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B
(149 residues)
|
|
|
|
|
|
Crystal structure of dusp10 mutant_n130a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B
(149 residues)
|
|
|
|
|
|
Prostatic acid phosphatase (pap) fragment (85-120)
|
|
|
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
|
|
|
Chain:
A
(36 residues)
|
|
|
|
|
|
Human ptprm domains fn3-4, in spacegroup p212121
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprm, ptprl1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293-f
|
|
|
Chains:
A, B
(225 residues)
|
|
|
|
|
|
Human ptprm domains fn3-4, in spacegroup p3221
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprm, ptprl1. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293-f
|
|
|
Chains:
A, B, C, D
(244 residues)
|
|
|
|
|
|
Human ptprk n-terminal domains mam-ig-fn1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprk, ptpk. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293-f
|
|
|
Chains:
A, B
(353 residues)
|
|
|
|
|
|
Shp2 in complex with allosteric imidazopyrazine inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(504 residues)
|
|
|
|
|
|
Shp2 in complex with a novel allosteric inhibitor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(485 residues)
|
|
|
|
|
|
Crystal structure of the ptpn3 pdz domain bound to the pbm tacE C- terminal peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn3, ptph1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(93 residues)
|
|
|
|
|
|
Crystal structure of drosophila melanogaster prl/cbs-pair domain complex
|
|
|
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: uex, 41ad, groupiii, l(2)41ad, cg42595. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: prl-1, bg:ds07473.3, prl, cg4993. Expression_system_taxid: 562
|
|
|
Chains:
C, D
(153 residues)
|
|
|
|
|
|
Room-temperature serial synchrotron crystallography (ssx) structure of apo ptp1b
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chain:
A
(284 residues)
|
|
|
|
|
|
Crystal structure of apo ptp1b d181a/q262a phosphatase domain
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a phosphatase domain in complex with a jak1 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(298 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a phosphatase domain with jak2 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(297 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a phosphatase domain with a jak3 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(298 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a phosphatase domain with tyk2 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(296 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a/c215a phosphatase domain with a jak2 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(301 residues)
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a/c215a phosphatase domain with jak2 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B
(281 residues)
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a/c215a phosphatase domain with tyk2 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(298 residues)
|
|
|
|
|
|
Crystal structure of ptp1b d181a/q262a/c215a phosphatase domain with monophosphorylated jak2 activation loop phosphopeptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chains:
A, B, C
(296 residues)
|
|
|
|
|
|
Crystal structure of thE C-terminal fg domain of tnc with the single fn domain of ptprz
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnc, hxb. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ptprz1, htpzp2, ptprz, ptprz2, ptpz.
|
|
|
Chain:
B
(101 residues)
|
|
|
|
|
|
Crystal structure of thE C-terminal fg domain of tnr with the single fn domain of ptprz
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnr. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ptprz1, htpzp2, ptprz, ptprz2, ptpz.
|
|
|
Chains:
B, D, F, H
(99 residues)
|
|
|
|
|
|
Wildtype ptp1b in complex with des4799
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Wildtype ptp1b in complex with des4884
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(283 residues)
|
|
|
|
|
|
Wildtype ptp1b in complex with des5742
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(287 residues)
|
|
|
|
|
|
Wildtype ptp1b in complex with des5743
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(298 residues)
|
|
|
|
|
|
Wildtype ptp1b in complex with des6016
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(281 residues)
|
|
|
|
|
|
Ptpn21 ferm
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn21, ptpd1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(285 residues)
|
|
|
|
|
|
Ptpn21 ptp domain c1108s mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn21, ptpd1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(286 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Ptpn21 ptp domain c1108s mutant in complex with src ptyr530 peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn21, ptpd1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
|
Chain:
A
(295 residues)
|
|
|
|
|
|
Small-molecule allosteric regulation mechanism of shp2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(477 residues)
|
|
|
|
|
|
Ptpn21 ferm ptp complex
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn21, ptpd1. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(292 residues)
|
|
|
|
|
|
Crystal structure of mpxv phosphatase
|
|
|
Source: Monkeypox virus. Organism_taxid: 10244. Gene: h1l, mpxv-cam1990_02-083, mpxv-congo_8-084, mpxv-cop-085, mpxv-gab1988_001-084, mpxv-ikubi-083, mpxv-m2940_fct-089, mpxv- m2957_lagos-089, mpxv-m3021_delta-089, mpxv-m5312_hm12_rivers-089, mpxv-m5320_m15_bayelsa-082, mpxv-nig_sev71_2_82-084, mpxv-pch-086, mpxv-singapore-089, mpxv-sl-085, mpxv-uk_p1-089, mpxv-uk_p2-089, mpxv-uk_p3-089, mpxv-usa2003_099_gr-089, mpxv-usa2003_206_dm-089, mpxv-usa2003_223_rs-089, mpxv-utc-080, mpxv-w_nigeria-084, mpxv-
|
|
|
Chain:
A
(170 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Vascular endothelial protein tyrosine phosphatase in complex with cpd- 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(282 residues)
|
|
|
|
|
|
Vascular endothelial protein tyrosine phosphatase in complex with cpd- 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprb, ptpb. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(287 residues)
|
|
|
|
|
|
Crystal structure of the ptpn3 pdz domain bound to the hpv18 e6 oncoprotein c-terminal peptide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn3, ptph1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Human papillomavirus 18. Organism_taxid: 333761
|
|
|
Chains:
A, C
(93 residues)
|
|
|
|
|
|
Cryo-em structure of cdk2-cyclin a in complex with cdc25a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdk2, cdkn2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: star. Bos taurus. Cattle.
|
|
|
Chain:
C
(190 residues)
|
|
|
|
|
|
Ptp1b in complex with 182
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(299 residues)
|
|
|
|
|
|
Crystal structure of human step (ptpn5) at cryogenic temperature (100 k) and ambient pressure (0.1 mpa)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of human step (ptpn5) at physiological temperature (310 k) and ambient pressure (0.1 mpa)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of human step (ptpn5) at cryogenic temperature (100 k) and high pressure (205 mpa)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Identification of gdc-1971 (rly-1971), a shp2 inhibitor designed for the treatment of solid tumors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(494 residues)
|
|
|
|
|
|
Identification of gdc-1971 (rly-1971), a shp2 inhibitor designed for the treatment of solid tumors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(501 residues)
|
|
|
|
|
|
Identification of gdc-1971 (rly-1971), a shp2 inhibitor designed for the treatment of solid tumors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(492 residues)
|
|
|
|
|
|
Identification of gdc-1971 (rly-1971), a shp2 inhibitor designed for the treatment of solid tumors
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(496 residues)
|
|
|
|
|
|
Human vh1-related dual-specificity phosphatase (vhr) complexed with 2- ((2,4-difluorobenzyl)amino)-2-oxoacetic acid
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp3, vhr. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(181 residues)
|
|
|
|
|
|
Human vh1-related dual-specificity phosphatase (vhr) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4- ol at two allosteric sites
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp3, vhr. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(179 residues)
|
|
|
|
|
|
Human vh1-related dual-specificity phosphatase (vhr) complexed with phosphate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp3, vhr. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chain:
A
(179 residues)
|
|
|
|
Bound ligand:
|
Het Group PO4
corresponds to
enzyme product phosphate
|
|
|
|
|
|
|
Human vh1-related dual-specificity phosphatase (vhr) complexed with hepes
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp3, vhr. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693
|
|
|
Chains:
A, B
(181 residues)
|
|
|
|
|
|
Human vh1-related dual-specificity phosphatase (vhr) in apo form
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp3, vhr. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(181 residues)
|
|
|
|
|
|
Crystal structure of ptpn2 with a protac
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9
|
|
|
Chains:
A, B
(279 residues)
|
|
|
|
|
|
Apo protein tyrosine phosphatase 1b (ptp1b) at high resolution (1.43 a) in space group p43212 with two distinctly ordered chains
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(281 residues)
|
|
|
|
|
|
Structure of sts-1 hp domain with rebamipide
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubash3b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(257 residues)
|
|
|
|
|
|
Structure of sts-1 hp domain with rebamipide derivative
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubash3b. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(253 residues)
|
|
|
|
|
|
Crystal structure of non-receptor protein tyrosine phosphatase shp2 in complex with inhibitor compound 7
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(493 residues)
|
|
|
|
|
|
Crystal structure of non-receptor protein tyrosine phosphatase shp2 in complex with inhibitor compound 24
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(491 residues)
|
|
|
|
|
|
Degrader-induced complex between ptpn2 and crbn-ddb1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ddb1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: crbn. Gene: ptpn2, ptpt. Expressed in: escherichia coli.
|
|
|
Chain:
C
(277 residues)
|
|
|
|
|
|
Cryo-em structure of human cd45 extracellular region in complex with adenoviral protein e3/49k
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptprc, cd45. Expressed in: homo sapiens. Expression_system_taxid: 9606. Human adenovirus 19a. Organism_taxid: 88059. Gene: 49k, e3.
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Chains:
A, B
(351 residues)
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The crystal structure of shp2 from biortus.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B
(484 residues)
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Crystal structure of shp2 in complex with jab-3186
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B
(485 residues)
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Structure of prostatic acid phosphatase in human semen
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Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: human seminal plasma
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Chains:
B, A
(347 residues)
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The crystal structure of ptp1b from biortus.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(300 residues)
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The crystal structure of ptprg from biortus.
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Source: Homo sapiens. Organism_taxid: 9606. Gene: ptprg, ptpg. Expressed in: prokaryote coculture. Expression_system_taxid: 2746493
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Chains:
A, B
(287 residues)
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Crystal structure of the ptpn21 ferm domain
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn21, ptpd1. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(281 residues)
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The crystal structure of shp1 from biortus.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn6, hcp, ptp1c. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(280 residues)
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Structure of the p38alpha-pepheptpm(16-31)(v31c ) complex
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Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: mapk14, crk1, csbp1, csbp2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human.
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Chain:
B
(16 residues)
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Crystal structure of the allosteric mkp5 mutant y435w
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B
(144 residues)
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Crystal structure of an mkp5 mutant, y435w, in complex with an allosteric inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B, C, D, E, F, G, H, I, J, K, L
(148 residues)
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Cryo-em structure of danio rerio voltage-sensing phosphatase (vsp) phosphatase domain
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Source: Danio rerio. Zebrafish. Organism_taxid: 7955. Gene: tpte, tpip, vsp, wu:fd20e11, wu:fi24b06. Expressed in: komagataella pastoris. Expression_system_taxid: 4922
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Chains:
A, B
(293 residues)
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Crystal structure of human ptpn2 catalytic domain
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(287 residues)
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Crystal structure of human ptpn2 in complex with active site inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(288 residues)
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Crystal structure of human ptpn2 in complex with allosteric inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn2, ptpt. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(276 residues)
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Pp2a:b55-eya3 substrate complex
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ppp2r1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ppp2r2a. Expressed in: homo sapiens. Expression_system_taxid: 9606.
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Chain:
D
(13 residues)
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Crystal structure of wild-type human ptp1b (ptpn1) at room temperature (298 k)
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(283 residues)
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Crystal structure of i19v mutant human ptp1b (ptpn1) at room temperature (298 k)
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(284 residues)
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Crystal structure of q78r mutant human ptp1b (ptpn1) at room temperature (298 k)
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(284 residues)
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Crystal structure of d245g mutant human ptp1b (ptpn1) at room temperature (298 k)
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn1, ptp1b. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(284 residues)
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Human vh1-related dual-specificity phosphatase (vhr) in distinct apo form
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp3, vhr. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chain:
A
(178 residues)
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Step (ptpn5) at high resolution with citrate bound in active site
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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Chain:
A
(282 residues)
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Step (ptpn5) with active-site disulfide bond and allosteric-site loop shift
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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Chain:
A
(272 residues)
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Acmnpv apical cap - c14 anchor complex only
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Source: Autographa californica nucleopolyhedrovirus. Organism_taxid: 46015. Organism_taxid: 46015
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Chain:
O
(168 residues)
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Structure of phosphocysteine intermediate of human prl1 phosphatase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptp4a1, prl1, ptpcaax1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(151 residues)
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Crystal structure shp2 tandem sh2 domains in complex with pzr doubly tyrosine phosphorylated itim peptide
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ptpn11, ptp2c, shptp2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
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Chain:
A
(205 residues)
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Pp2a-b55 holoenzyme with eya3
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ppp2r1a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: ppp2r2a. Gene: ppp2ca. Gene: eya3.
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Chain:
D
(22 residues)
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Crystal structure of an mkp5 allosteric loop mutant, s446g, in complex with an allosteric inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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Chains:
A, B, C, D, E, F
(148 residues)
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Crystal structure of an mkp5 allosteric loop mutant, n448a
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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Chains:
A, B
(147 residues)
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Crystal structure of an mkp5 mutant, y435f, in complex with an allosteric inhibitor
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|
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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|
Chains:
A, B, C, D, E, F
(148 residues)
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Crystal structure of an mkp5 allosteric loop mutant, p447v, in complex with an allosteric inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B, C, D, E, F
(148 residues)
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Crystal structure of the mkp5 loop mutant n448a in complex with the allosteric inhibitor
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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Chains:
A, B, C, D, E, F
(147 residues)
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A crystal structure of dusp10 loop mutant i445a
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dusp10, mkp5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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|
|
Chains:
A, B, C, D, E, F, G, H, I, J, K, L
(147 residues)
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[IntEnz]
[ExPASy]
[KEGG]
