EC 3.1.13.5 - ribonuclease D.

_EC 3.1.13.5 ribonuclease D.

1 PDB entries

EC 3.-.-.- Hydrolases. [52,127 PDB entries]

EC 3.1.-.- Acting on ester bonds. [12,902 PDB entries]

EC 3.1.13.- Exoribonucleases producing 5'-phosphomonoesters. [1,717 PDB entries]

EC 3.1.13.5 ribonuclease D. [1 PDB entries]

1yt3

Reaction: Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.

Other name(s): RNase D.

Comments: Alteration of the 3'-terminal base has no effect on the rate of hydrolysis whereas modification of the 3'-terminal sugar has a major effect. tRNA terminating with a 3'-phosphate is completely inactive. This enzyme can convert a tRNA precursor into a mature tRNA.

Links: [IntEnz] [ExPASy] [KEGG]

There are 1 PDB entries in enzyme class E.C.3.1.13.5

PDB code Protein

1yt3

Crystal structure of escherichia coli rnase d, an exoribonuclease involved in structured RNA processing

Source: Escherichia coli. Organism_taxid: 562. Gene: rnd. Expressed in: escherichia coli. Expression_system_taxid: 562.

Chain: A (375 residues) CATH domains: 3.30.420.10 1.10.150.80 1.10.150.80

Reaction:		Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.

Other name(s):		RNase D.

Comments:		Alteration of the 3'-terminal base has no effect on the rate of hydrolysis whereas modification of the 3'-terminal sugar has a major effect. tRNA terminating with a 3'-phosphate is completely inactive. This enzyme can convert a tRNA precursor into a mature tRNA.

Links:		[IntEnz] [ExPASy] [KEGG]