_EC 3.1.1.118 phospholipid sn-1 acylhydrolase.

0 PDB entries

EC 3.-.-.- Hydrolases. [52,127 PDB entries] EC 3.1.-.- Acting on ester bonds. [12,902 PDB entries] EC 3.1.1.- Carboxylic ester hydrolases. [2,187 PDB entries] EC 3.1.1.118 phospholipid sn-1 acylhydrolase. [-]

Reaction:		(1) a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = a 2-acyl- sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+). (2) a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 2-acyl-sn-glycerol 3-phosphate + a fatty acid + H(+).
		1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-acyl- sn-glycero-3-phospho-D-myo-inositol + fatty acid + H(+) 1,2-diacyl-sn-glycero-3-phosphate + H2O = 2-acyl-sn-glycerol 3-phosphate + fatty acid + H(+) Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Other name(s):		PA-PLA1. phosphatidic acid-preferring phospholipase A1. phospholipase DDHD1.
Comments:		The human enzyme shows broad specificity, and has a preference for phosphatidate over other phospholipids. Unlike Ec 3.1.1.32 it is also active against phosphatidylinositol. It is not active toward acyl groups linked at the sn-2 position.
Links:		[IntEnz]   [ExPASy]   [KEGG]

There are no PDB entries in enzyme class E.C.3.1.1.118