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PDB code
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Protein
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Branched-chain amino acid aminotransferase from escherichia coli
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Source: Escherichia coli. Organism_taxid: 562
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Chains:
A, B, C
(295 residues)
CATH domains:
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Bound ligand:
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystallographic structure of human branched chain amino acid aminotransferase (mitochondrial) complexed with pyridoxal-5'- phosphate at 1.95 angstroms (orthorhombic form)
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(365 residues)
CATH domains:
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Bound ligand:
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of human branched chain amino acid aminotransferase (mitochondrial) complexed with pyridoxal-5'-phosphate at 2.5 angstroms (monoclinic form).
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(365 residues)
CATH domains:
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Bound ligand:
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Human branched chain amino acid aminotransferase (mitochondrial): three dimensional structure of enzyme inactivated by tris bound to the pyridoxal-5'-phosphate on one end and active site lys202 nz on the other.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(365 residues)
CATH domains:
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Bound ligands:
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Het Group TRS
is 41.67% similar to
enzyme product L-glutamate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of eschelichia coli branched-chain amino acid aminotransferase.
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Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B, C
(298 residues)
CATH domains:
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Bound ligand:
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of eschelichia coli branched-chain amino acid aminotransferase.
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Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B, C
(304 residues)
CATH domains:
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Bound ligands:
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Het Group 2ML
is 90.00% similar to
enzyme reactant L-leucine
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of escherichia coli branched-chain amino acid aminotransferase.
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Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B, C
(304 residues)
CATH domains:
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Bound ligands:
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Het Group 4MV
is 88.89% similar to
enzyme reactant L-leucine
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of eschelichia coli branched-chain amino acid aminotransferase
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Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B, C
(304 residues)
CATH domains:
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Bound ligands:
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Het Group GUA
is 90.00% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of eschelichia coli branched-chain amino acid aminotransferase
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Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B, C
(304 residues)
CATH domains:
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Bound ligand:
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Het Group PGU
is 57.69% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Human branched chain amino acid aminotransferase (mitochondrial): three dimensional structure of enzyme in its ketimine form with the substrate l-isoleucine
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(360 residues)
CATH domains:
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Bound ligands:
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Het Group ACY
is 44.44% similar to
enzyme reactant L-leucine
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Het Group GOL
is 50.00% similar to
enzyme product 4-methyl-2-oxopentanoate
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Het Group ILP
is 60.00% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Human branched chain amino acid aminotransferase : three dimensional structure of the enzyme in its pyridoxamine phosphate form.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(365 residues)
CATH domains:
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Bound ligands:
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Het Group KIV
is 70.00% similar to
enzyme product 4-methyl-2-oxopentanoate
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Het Group PMP
is 88.24% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase
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Source: Thermus thermophilus. Organism_taxid: 274. Gene: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B, C
(297 residues)
CATH domains:
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Bound ligands:
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Het Group MPD
is 50.00% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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X-ray crystal structure of human mitochondrial branched chain aminotransferase (bcatm) complexed with gabapentin
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mitochondrial bcat. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(363 residues)
CATH domains:
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Bound ligands:
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Het Group GBN
is 46.67% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of human branched chain amino acid transaminase in a complex with an inhibitor, c16h10n2o4f3scl, and pyridoxal 5' phosphate.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, D, G, J
(366 residues)
CATH domains:
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Bound ligand:
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of oxidized human cytosolic branched-chain aminotransferase complexed with 4-methylvalerate
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(358 residues)
CATH domains:
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Bound ligands:
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Het Group 4MV
is 88.89% similar to
enzyme reactant L-leucine
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of oxidized human cytosolic branched-chain aminotransferase complexed with gabapentin
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B
(358 residues)
CATH domains:
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Bound ligands:
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Het Group GBN
is 46.67% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of reduced human cytosolic branched-chain aminotransferase complexed with gabapentin
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
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Chains:
A, B
(359 residues)
CATH domains:
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Bound ligands:
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Het Group GBN
is 46.67% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with 4-methylvaleric acid
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Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B, C
(297 residues)
CATH domains:
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Bound ligands:
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Het Group 4MV
is 88.89% similar to
enzyme reactant L-leucine
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase with pyridoxamine 5'-phosphate
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Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B, C, D, E, F
(297 residues)
CATH domains:
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Bound ligands:
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Het Group MPD
is 70.00% similar to
enzyme product 4-methyl-2-oxopentanoate
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Het Group PMP
is 88.24% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate
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Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B, C, D, E, F
(294 residues)
CATH domains:
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Bound ligands:
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Het Group MPD
is 70.00% similar to
enzyme product 4-methyl-2-oxopentanoate
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Het Group PPE
is 57.69% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of t.Th.Hb8 branched-chain amino acid aminotransferase complexed with gabapentin
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Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B, C
(297 residues)
CATH domains:
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Bound ligands:
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Het Group GBN
is 46.67% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of cys315ala-cys318ala mutant of human mitochondrial branched chain aminotransferase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(363 residues)
CATH domains:
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Bound ligands:
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Het Group COI
corresponds to
enzyme product 4-methyl-2-oxopentanoate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of cys315ala mutant of human mitochondrial branched chain aminotransferase complexed with its substrate mimic, n-methyl leucine.
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, eca40. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(357 residues)
CATH domains:
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Bound ligands:
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Het Group MLE
is 90.00% similar to
enzyme reactant L-leucine
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of cys318ala mutant of human mitochondrial branched chain aminotransferase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, eca40. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(358 residues)
CATH domains:
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Bound ligands:
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Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
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Het Group ACY
is 40.00% similar to
enzyme product L-glutamate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of cys315ala mutant of human mitochondrial branched chain aminotransferase
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, eca40. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(357 residues)
CATH domains:
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Bound ligands:
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Het Group ACY
is 40.00% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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X-ray crystal structure of oxidized human mitochondrial branched chain aminotransferase (hbcatm)
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Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, eca40. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Chains:
A, B
(348 residues)
CATH domains:
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Bound ligand:
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of a putative branched-chain amino acid aminotransferase (tm0831) from thermotoga maritima at 2.15 a resolution
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Source: Thermotoga maritima msb8. Organism_taxid: 243274. Strain: msb8 / dsm 3109 / jcm 10099. Atcc: 43589. Gene: tm0831, ilve. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B, C, D
(274 residues)
CATH domains:
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Bound ligands:
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Het Group CIT
is 64.29% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
corresponds to
enzyme cofactor pyridoxal 5'-phosphate
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Structural analysis of mycobacterial branched chain aminotransferase- implications for inhibitor design
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Source: Mycobacterium smegmatis. Organism_taxid: 246196. Gene: ilve, msmeg_4276. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(363 residues)
CATH domains:
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Bound ligand:
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Het Group GOL
is 50.00% similar to
enzyme product 4-methyl-2-oxopentanoate
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Structural analysis of mycobacterial branched chain aminotransferase- implications for inhibitor design
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Source: Mycobacterium smegmatis. Organism_taxid: 1772. Gene: ilve, msmeg_4276. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(363 residues)
CATH domains:
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Bound ligands:
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Het Group OBZ
is 50.00% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of ilve a branched chain amino acid transaminase from mycobacterium tuberculosis
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Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: ilve, mt2266, mtcy190.21c, rv2210c. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(335 residues)
CATH domains:
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Bound ligand:
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Het Group PMP
is 88.24% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of mycobacterium smegmatis branched chain aminotransferase in complex with pyridoxal-5'-phosphate at 1.9 angstrom.
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Source: Mycobacterium smegmatis. Organism_taxid: 1772. Gene: ilve, msmeg_4276. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(363 residues)
CATH domains:
|
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Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
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Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
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Crystal structure of putative 4-amino-4-deoxychorismate lyase. (Yp_094631.1) from legionella pneumophila subsp. Pneumophila str. Philadelphia 1 at 1.78 a resolution
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Source: Legionella pneumophila. Organism_taxid: 272624. Strain: philadelphia 1 / atcc 33152 / dsm 7513. Gene: lpg0595. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(268 residues)
CATH domains:
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Crystal structure of a putative amino-acid aminotransferase (np_104211.1) from mesorhizobium loti at 2.30 a resolution
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Source: Mesorhizobium loti. Organism_taxid: 381. Gene: mlr3007. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B, C, D, E, F, G, H
(215 residues)
CATH domains:
|
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Bound ligand:
|
Het Group EDO
is 44.44% similar to
enzyme product 4-methyl-2-oxopentanoate
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Crystal structure of a putative aminotransferase (ncgl2491) from corynebacterium glutamicum atcc 13032 at 1.60 a resolution
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Source: Corynebacterium glutamicum. Organism_taxid: 196627. Strain: atcc 13032 kitasato. Gene: cgl2580. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chain:
A
(245 residues)
CATH domains:
|
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Bound ligand:
|
Het Group EDO
is 44.44% similar to
enzyme product 4-methyl-2-oxopentanoate
|
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Crystal structure of branched-chain amino acid aminotransferase from burkholderia pseudomallei
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Source: Burkholderia pseudomallei. Organism_taxid: 28450. Strain: 1710b. Gene: ilve, bpsl0793. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Chains:
A, B, C, D, E, F
(303 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group GOL
is 50.00% similar to
enzyme product 4-methyl-2-oxopentanoate
|
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Crystal structures of branched-chain aminotransferase from deinococcus radiodurans complexes with alpha-ketoisocaproate and l-glutamate suggest its radio-resistance for catalysis
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Source: Deinococcus radiodurans. Organism_taxid: 1299. Strain: r1. Gene: dr_1626. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B
(335 residues)
CATH domains:
|
|
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Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
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Crystal structures of branched-chain aminotransferase from deinococcus radiodurans complexes with alpha-ketoisocaproate and l-glutamate suggest its radio-resistance for catalysis
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Source: Deinococcus radiodurans. Organism_taxid: 1299. Strain: r1. Gene: dr_1626. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Chains:
A, B, C, D
(335 residues)
CATH domains:
|
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Bound ligands:
|
Het Group COI
corresponds to
enzyme product 4-methyl-2-oxopentanoate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
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Crystal structures of branched-chain aminotransferase from deinococcus radiodurans complexes with alpha-ketoisocaproate and l-glutamate suggest its radio-resistance for catalysis
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Source: Deinococcus radiodurans. Organism_taxid: 1299. Strain: r1. Gene: dr_1626. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
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|
Chains:
A, B
(335 residues)
CATH domains:
|
|
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Bound ligands:
|
Het Group GLU
corresponds to
enzyme product L-glutamate
|
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|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
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First crystal structure of an (r)-selective omega-transaminase from aspergillus terreus
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Source: Aspergillus terreus. Organism_taxid: 33178. Strain: nih 2624 / fgsc a1156. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold / top10f'.
|
|
|
Chains:
A, B
(325 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group PDG
is 40.00% similar to
enzyme product L-glutamate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
The (r)-selective transaminase from nectria haematococca
|
|
|
Source: Nectria haematococca mpvi. Organism_taxid: 70791. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
|
|
|
Chains:
A, B
(322 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
The (r)-selective transaminase from nectria haematococca with inhibitor bound
|
|
|
Source: Nectria haematococca mpvi. Organism_taxid: 70791
|
|
|
Chain:
A
(322 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group TRS
is 41.67% similar to
enzyme reactant L-leucine
|
|
|
Het Group PXG
is 57.69% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of the branched-chain aminotransferase from streptococcus mutans
|
|
|
Source: Streptococcus mutans. Organism_taxid: 1309. Gene: ilve, smu_1203. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chain:
A
(340 residues)
CATH domains:
|
|
|
|
|
|
Structure of aminotransferase ilve2 from sinorhizobium meliloti complexed with plp
|
|
|
Source: Sinorhizobium meliloti. Ensifer meliloti. Organism_taxid: 266834. Strain: 1021. Gene: ilve2, r00971, smc00042. Expressed in: escherichia coli. Expression_system_taxid: 469008.
|
|
|
Chains:
A, B
(283 residues)
CATH domains:
|
|
|
|
|
|
X-ray crystal structure of an aminotransferase from brucella abortus bound to the co-factor plp
|
|
|
Source: Brucella abortus. Organism_taxid: 359391. Strain: 2308. Gene: bab2_0572. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(280 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group EDO
is 44.44% similar to
enzyme product 4-methyl-2-oxopentanoate
|
|
|
|
|
|
|
X-ray crystal structure at 2.20a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a pyrazolopyrimidinone fragment and an internal aldimine linked plp.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(356 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group EDO
is 40.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 2.20a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a pyrazolopyrimidinone fragment and an internal aldimine linked plp.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(360 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 2.17a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a triazolopyrimidinone compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(354 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group EDO
is 40.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 1.86a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a pyrazolopyrimidinone compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(355 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 1.82a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a pyrrolidine amide compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(353 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 1.70a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a 4-chloro-2- fluoro substituted pyrazolopyrimidinone compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(353 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain aminotransferase from thermophilic archaea thermoproteus uzoniensis
|
|
|
Source: Thermoproteus uzoniensis (strain 768-20). Organism_taxid: 999630. Gene: tuzn_1299. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(296 residues)
CATH domains:
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain aminotransferase from thermophilic archaea geoglobus acetivorans
|
|
|
Source: Geoglobus acetivorans. Organism_taxid: 565033. Gene: gace_1900. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(282 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 1.61a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a biphenyl pyrrolidine ether compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(358 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group EDO
is 40.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain aminotransferase from thermophilic archaea geoglobus acetivorans complexed with alpha-ketoglutarate
|
|
|
Source: Geoglobus acetivorans. Organism_taxid: 565033. Gene: gace_1900. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(290 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group AKG
corresponds to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure of human mitochondrial branched chain aminotransferase (bcatm) complexed with a 2-aryl benzimidazole compound and an internal aldimine linked plp cofactor
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(359 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 2.06a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a benzisoxazole compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(361 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group NVU
is 57.14% similar to
enzyme reactant L-leucine
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 2.31a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a tetrahydroquinoline compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(361 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group EDO
is 40.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 2.40a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a tetrahydronaphthalenyl compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(363 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 1.94a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a thienopyrimidine compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(360 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 2.40a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a biaryl amide compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(354 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 1.65a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a thiazole compound and pmp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(358 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 50.00% similar to
enzyme product 4-methyl-2-oxopentanoate
|
|
|
Het Group PMP
is 88.24% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 1.81a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with an aryl acetate compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(363 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
X-ray crystal structure at 2.12a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a biarl amide compound and an internal aldimine linked plp cofactor.
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
|
Chains:
A, B
(359 residues)
CATH domains:
|
|
|
|
Bound ligands:
|
Het Group EDO
is 40.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Single amino acid variant of human mitochondrial branched chain amino acid aminotransferase 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(364 residues)
|
|
|
|
Bound ligands:
|
Het Group EDO
is 40.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Archaeal branched-chain amino acid aminotransferase from archaeoglobus fulgidus; holoform
|
|
|
Source: Archaeoglobus fulgidus (strain atcc 49558 / vc- 16 / dsm 4304 / jcm 9628 / nbrc 100126). Organism_taxid: 224325. Strain: atcc 49558 / vc-16 / dsm 4304 / jcm 9628 / nbrc 100126. Gene: ilve, af_0933. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(287 residues)
|
|
|
|
Bound ligand:
|
Het Group TAM
is 50.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
|
|
|
|
Thermophilic archaeal branched-chain amino acid transaminases from geoglobus acetivorans and archaeoglobus fulgidus: biochemical and structural characterisation
|
|
|
Source: Archaeoglobus fulgidus (strain atcc 49558 / vc- 16 / dsm 4304 / jcm 9628 / nbrc 100126). Organism_taxid: 224325. Strain: atcc 49558 / vc-16 / dsm 4304 / jcm 9628 / nbrc 100126. Gene: ilve, af_0933. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(287 residues)
|
|
|
|
Bound ligands:
|
Het Group TAM
is 50.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PXG
is 57.69% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Structure of mycobacterium tuberculosis ilve, a branched-chain amino acid transaminase, in complex with d-cycloserine derivative
|
|
|
Source: Mycobacterium tuberculosis (strain atcc 25618 / h37rv). Organism_taxid: 83332. Strain: atcc 25618 / h37rv. Gene: ilve, rv2210c, mtcy190.21c. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(326 residues)
|
|
|
|
Bound ligand:
|
Het Group 7TS
is 65.22% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum in plp-form (holo-form)
|
|
|
Source: Thermobaculum terrenum atcc baa-798. Organism_taxid: 525904. Gene: ilve, tter_1720. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(307 residues)
|
|
|
|
Bound ligands:
|
Het Group ACT
is 40.00% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of the branched-chain-amino-acid aminotransferase from haliangium ochraceum
|
|
|
Source: Synthetic: yes. Haliangium ochraceum (strain dsm 14365 / jcm 11303 / smp-2). Organism_taxid: 502025
|
|
|
Chains:
A, B, C, D, E, F
(305 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched chain amino acid aminotransferase from pseudomonas aeruginosa
|
|
|
Source: Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1). Organism_taxid: 208964. Strain: atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1. Gene: ilve, pa5013. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D, E, F
(301 residues)
|
|
|
|
|
|
Oxidized human branched chain aminotransferase mutant c318a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat2, bcatm, bct2, eca40. Expressed in: escherichia phage ecszw-2. Expression_system_taxid: 2419741
|
|
|
Chains:
A, B
(352 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum in pmp-form
|
|
|
Source: Thermobaculum terrenum (strain atcc baa-798 / ynp1). Organism_taxid: 525904. Strain: atcc baa-798 / ynp1. Gene: ilve, tter_1720. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(307 residues)
|
|
|
|
Bound ligand:
|
Het Group PMP
is 88.24% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain aminotransferase from thermophilic archaea thermoproteus uzoniensis with norvaline
|
|
|
Source: Thermoproteus uzoniensis 768-20. Organism_taxid: 999630. Gene: ilve, tuzn_1299. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C
(297 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain amino acid aminotransferase from giardia lamblia atcc 50803
|
|
|
Source: Giardia intestinalis. Giardia lamblia. Organism_taxid: 184922. Strain: atcc 50803 / wb clone c6. Atcc: 50803. Gene: gl50803_006184, gl50803_6184. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
|
|
|
Chains:
A, B, C, D
(357 residues)
|
|
|
|
Bound ligand:
|
Het Group EDO
is 44.44% similar to
enzyme product 4-methyl-2-oxopentanoate
|
|
|
|
|
|
|
Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum (m3 mutant).
|
|
|
Source: Thermobaculum terrenum (strain atcc baa-798 / ynp1). Organism_taxid: 525904. Strain: atcc baa-798 / ynp1. Gene: ilve, tter_1720. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(309 residues)
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of branched-chain amino acid aminotransferase from thermobaculum terrenum (m4 mutant)
|
|
|
Source: Thermobaculum terrenum (strain atcc baa-798 / ynp1). Organism_taxid: 525904. Strain: atcc baa-798 / ynp1. Gene: ilve, tter_1720. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(302 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and substrate mimic 3-phenylpropionate
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(362 residues)
|
|
|
|
Bound ligands:
|
Het Group HCI
is 66.67% similar to
enzyme reactant L-leucine
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and compound a
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(365 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and inhibitor compound 1
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D
(365 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and inhibitor compound 2
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D
(365 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and inhibitor compound 10
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(365 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and inhibitor compound 12
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(365 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and small molecule inhibitor compound 21(5-f)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(362 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and small molecule inhibitor compound 24(5-f)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(361 residues)
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and small molecule inhibitor compound 35
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(364 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and small molecule inhibitor compound 38
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(364 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of human cytosolic branched-chain aminotransferase (bcat1) in complex with plp and small molecule inhibitor bay-069 (compound 36)
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B
(364 residues)
|
|
|
|
Bound ligand:
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Transaminase of gamma-proteobacterium
|
|
|
Source: Luminiphilus syltensis nor5-1b. Organism_taxid: 565045. Gene: ilve_3, nor51b_30. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(296 residues)
|
|
|
|
Bound ligands:
|
Het Group GOL
is 45.45% similar to
enzyme reactant 2-oxoglutarate
|
|
|
Het Group PLP
is 93.75% similar to
enzyme cofactor pyridoxal 5'-phosphate
|
|
|
|
|
|
|
Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis (holo form).
|
|
|
Source: Haliscomenobacter hydrossis (strain atcc 27775 / dsm 1100 / lmg 10767 / o). Organism_taxid: 760192. Strain: atcc 27775 / dsm 1100 / lmg 10767 / o. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of d-aminoacid transaminase from haliscomenobacter hydrossis in its intermediate form
|
|
|
Source: Haliscomenobacter hydrossis dsm 1100. Organism_taxid: 760192. Strain: atcc 27775 / dsm 1100 / lmg 10767 / o. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(275 residues)
|
|
|
|
|
|
Crystal structure of aminotransferase-like protein from variovorax paradoxus
|
|
|
Source: Variovorax paradoxus b4. Organism_taxid: 1246301. Gene: vapa_1c54540. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, C, D, E, F
(300 residues)
|
|
|
|
|
|
Crystal structure of d-amino acid aminotrensferase from haliscomenobacter hydrossis complexed with d-cycloserine
|
|
|
Source: Haliscomenobacter hydrossis. Organism_taxid: 2350. Strain: atcc 27775 / dsm 1100 / lmg 10767 / o. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(283 residues)
|
|
|
|
|
|
Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis point mutant r90i (holo form)
|
|
|
Source: Haliscomenobacter hydrossis dsm 1100. Organism_taxid: 760192. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(281 residues)
|
|
|
|
|
|
Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis point mutant r90i complexed with phenylhydrazine
|
|
|
Source: Haliscomenobacter hydrossis dsm 1100. Organism_taxid: 760192. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis in the holo form obtained at ph 7.0
|
|
|
Source: Haliscomenobacter hydrossis dsm 1100. Organism_taxid: 760192. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(282 residues)
|
|
|
|
|
|
Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis (apo form) after 15 sec of soaking with phenylhydrazine
|
|
|
Source: Haliscomenobacter hydrossis dsm 1100. Organism_taxid: 760192. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(271 residues)
|
|
|
|
|
|
Crystal structure of d-amino acid transaminase from haliscomenobacter hydrossis complexed with 3-aminooxypropionic acid
|
|
|
Source: Haliscomenobacter hydrossis dsm 1100. Organism_taxid: 760192. Gene: halhy_2446. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(279 residues)
|
|
|
|
|
|
Engineering omega-amine transaminase for extending substrate scope by ancestral sequence reconstruction
|
|
|
Source: Aspergillus terreus. Organism_taxid: 33178. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
|
|
|
Chains:
A, B, C, D
(321 residues)
|
|
|
|
Bound ligand:
|
Het Group LMR
is 63.64% similar to
enzyme product 4-methyl-2-oxopentanoate
|
|
|
|
|
|
|
Bcat mutant
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B, E, F
(364 residues)
|
|
|
|
|
|
Bcat mutant 36e
|
|
|
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bcat1, bct1, eca39. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chains:
A, B
(358 residues)
|
|
|
|
|
|
Structure of tf9 mutant of aminotransferase from mycolicibacterium neoaurum in complex with llp and g4o
|
|
|
Source: Mycolicibacterium neoaurum vkm ac-1815d. Organism_taxid: 700508. Gene: d174_04695. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B, C, D
(310 residues)
|
|
|
|
|
|
Crystal structure of monomeric plp-dependent transaminase from desulfobacula toluolica in p 21 21 21 space group
|
|
|
Source: Desulfobacula toluolica. Organism_taxid: 28223. Gene: dat, tol2_c39420. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
|
Chain:
A
(246 residues)
|
|
|
|
Bound ligand:
|
Het Group GOL
is 71.43% similar to
enzyme product pyruvate
|
|
|
|
|
|
|
Crystal structure of aminotransferase-like protein from variovorax paradoxus mutant n174k
|
|
|
Source: Variovorax paradoxus b4. Organism_taxid: 1246301. Gene: vapa_1c54540. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
|
Chains:
A, B, C
(300 residues)
|
|
|
[IntEnz]
[ExPASy]
[KEGG]
