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| _EC 2.3.1.299 sphingoid base N-stearoyltransferase. | 0 PDB entries | |||||||||||||||
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| Reaction: | a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base + CoA + H(+). | ||||||||||
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| Other name(s): | mammalian ceramide synthase 1. | ||||||||||
| Comments: | Mammals have six ceramide synthases that exhibit relatively strict specificity regarding the chain-length of their acyl-CoA substrates. Ceramide synthase 1 (CERS1) is structurally and functionally distinctive from all other Cers enzymes, and is specific for stearoyl-CoA as the acyl donor. It can use multiple sphingoid bases including sphinganine, sphingosine, and phytosphingosine. | ||||||||||
| Links: |
[IntEnz]
[ExPASy]
[KEGG]
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There are no PDB entries in enzyme class E.C.2.3.1.299