_EC 2.3.1.299 sphingoid base N-stearoyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [47,784 PDB entries]
EC 2.3.-.- Acyltransferases. [6,129 PDB entries]
EC 2.3.1.- Transferring groups other than amino-acyl groups. [3,260 PDB entries]
EC 2.3.1.299 sphingoid base N-stearoyltransferase. [-]

Reaction: a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base + CoA + H(+).
 

sphingoid base
+ octadecanoyl-CoA
= N-octadecanoyl-sphingoid base
+
CoA
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): mammalian ceramide synthase 1.
Comments: Mammals have six ceramide synthases that exhibit relatively strict specificity regarding the chain-length of their acyl-CoA substrates. Ceramide synthase 1 (CERS1) is structurally and functionally distinctive from all other Cers enzymes, and is specific for stearoyl-CoA as the acyl donor. It can use multiple sphingoid bases including sphinganine, sphingosine, and phytosphingosine.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.2.3.1.299