_EC 2.3.1.243 acyl-Kdo2-lipid Iva acyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [47,965 PDB entries]
EC 2.3.-.- Acyltransferases. [6,182 PDB entries]
EC 2.3.1.- Transferring groups other than amino-acyl groups. [3,274 PDB entries]
EC 2.3.1.243 acyl-Kdo2-lipid Iva acyltransferase. [-]

Reaction: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid Iva + a fatty acyl- [ACP] = an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + holo-[ACP].
 


tetradecanoyl-[acyl-carrier protein]
+ (Kdo)(2)-(dodecanoyl)-lipid IV(A)
=
Kdo(2)-lipid A
+
holo-[acyl-carrier protein]
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): acyl-Kdo2-lipid Iva myristoyltransferase. myristoyl-[acyl-carrier protein]:alpha-Kdo-(2->4)-alpha-Kdo-(2->6)- (dodecanoyl)-lipid Iva O-myristoyltransferase.
Comments: The enzyme is involved in the biosynthesis of the phosphorylated outer membrane glycolipid lipid A. It transfers an acyl group to the 3-O position of the 3R-hydroxyacyl already attached at the 2-O position of the non-reducing glucosamine molecule. The enzyme from the bacterium Escherichia coli is specific for myristoyl (C14) acyl groups, giving the enzyme its previous accepted name. However, enzymes from different species accept highly variable substrates.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.2.3.1.243