EC 1.4.9.2 - aralkylamine dehydrogenase (azurin).

_EC 1.4.9.2 aralkylamine dehydrogenase (azurin).

27 PDB entries

EC 1.-.-.- Oxidoreductases. [21,428 PDB entries]

EC 1.4.-.- Acting on the CH-NH2 group of donors. [697 PDB entries]

EC 1.4.9.- With a copper protein as acceptor. [68 PDB entries]

EC 1.4.9.2 aralkylamine dehydrogenase (azurin). [27 PDB entries]

2agl

Reaction: an aralkylamine + 2 oxidized [azurin] + H2O = an aromatic aldehyde + 2 reduced [azurin] + NH4(+) + 2 H(+).

aralkylamine
+ 2 × oxidized [azurin]
+ H2O
=
aromatic aldehyde
+ 2 × reduced [azurin]
+ NH4(+)
+ 2 × H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): aromatic amine dehydrogenase. arylamine dehydrogenase.

Comments: Phenazine methosulfate can act as acceptor. Acts on aromatic amines and, more slowly, on some long-chain aliphatic amines, but not on methylamine or ethylamine. Formerly Ec 1.4.99.4.

Links: [IntEnz] [ExPASy] [KEGG]

There are 27 PDB entries in enzyme class E.C.1.4.9.2

PDB code Protein

2agl

Crystal structure of the phenylhydrazine adduct of aromatic amine dehydrogenase from alcaligenes faecalis

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group PHZ is 60.00% similar to enzyme product aromatic aldehyde

2agw

Crystal structure of tryptamine-reduced aromatic amine dehydrogenase (aadh) from alcaligenes faecalis in complex with tryptamine

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group TSS is 53.85% similar to enzyme product aromatic aldehyde

2agx

Crystal structure of the schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (aadh) with tryptamine. P212121 form

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group TSH is 53.85% similar to enzyme product aromatic aldehyde

2agy

Crystal structure of the schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (aadh) with tryptamine. Monoclinic form

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group TSH is 53.85% similar to enzyme product aromatic aldehyde

2agz

Crystal structure of the carbinolamine intermediate in the reductive half-reaction of aromatic amine dehydrogenase (aadh) with tryptamine. F222 form

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group TSC is 61.54% similar to enzyme product aromatic aldehyde

2ah0

Crystal structure of the carbinolamine intermediate in the reductive half-reaction of aromatic amine dehydrogenase (aadh) with tryptamine. Monoclinic form

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group TSC is 61.54% similar to enzyme product aromatic aldehyde

2ah1

Crystal structure of aromatic amine dehydrogenase (aadh) from alcaligenes faecalis

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

2h3x

Crystal structure of an electron transfer complex between aromatic amine dehydrogenase and azurin from alcaligenes faecalis (form 3)

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: A, B, D, E (359 residues) CATH domain: 2.130.10.10

2h47

Crystal structure of an electron transfer complex between aromatic amine dephydrogenase and azurin from alcaligenes faecalis (form 1)

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: A, B, D, E, F, G, H, I (360 residues) CATH domain: 2.130.10.10

2hj4

Crystal structure of alcaligenes faecalis aadh complex with p- nitrobenzylamine

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group PNZ is 58.33% similar to enzyme product aromatic aldehyde

2hjb

Crystal structure of alcaligenes faecalis aadh in complex with p- methoxybenzylamine

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group PZM is 63.64% similar to enzyme product aromatic aldehyde

2hkm

Crystal structure of the schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (aadh) with phenylethylamine.

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group PEA is 70.00% similar to enzyme product aromatic aldehyde

2hkr

Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (aadh) with p-methoxyphenylethylamine

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Gene: aaub. Expressed in: escherichia coli. Expression_system_taxid: 562

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group ZHZ is 66.67% similar to enzyme product aromatic aldehyde

2hxc

Crystal structure of the benzylamine complex of aromatic amine dehydrogenase in n-semiquinone form

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group ABN is 77.78% similar to enzyme product aromatic aldehyde

2i0r

Crystal structure of aromatic amine dehydrogenase ttq-formamide adduct

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: D, H, A, B (124 residues) CATH domain: 2.60.30.10

2i0s

Crystal structure of aromatic amine dehydrogenase ttq- phenylacetaldehyde adduct

Source: Alcaligenes faecalis. Organism_taxid: 511. Organism_taxid: 511

Chains: D, H, A, B (124 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group HY1 is 88.89% similar to enzyme product aromatic aldehyde

2i0t

Crystal structure of phenylacetaldehyde derived r-carbinolamine adduct of aromatic amine dehydrogenase

Source: Alcaligenes faecalis. Organism_taxid: 511. Organism_taxid: 511

Chains: D, H, A, B (121 residues) CATH domain: 2.60.30.10

2iaa

Crystal structure of an electron transfer complex between aromatic amine dephydrogenase and azurin from alcaligenes faecalis (form 2)

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: A, B, D, E (359 residues) CATH domain: 2.130.10.10

2iup

Crystal structure of dithionite-reduced aromatic amine dehydrogenase (aadh) from alcaligenes faecalis

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: A, B, D, H (360 residues) CATH domain: 2.130.10.10

2iuq

Crystal structure of dithionite-reduced aromatic amine dehydrogenase (aadh) from alcaligenes faecalis in complex with tryptamine

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: A, B, D, H (360 residues) CATH domain: 2.130.10.10

Bound ligand: Het Group TSS is 53.85% similar to enzyme product aromatic aldehyde

2iur

Crystal structure of n-quinol form of aromatic amine dehydrogenase (aadh) from alcaligenes faecalis, form a cocrystal

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: A, B, D, H (360 residues) CATH domain: 2.130.10.10

2iuv

Crystal structure of n-quinol form of aromatic amine dehydrogenase (aadh) from alcaligenes faecalis, form b

Source: Alcaligenes faecalis. Organism_taxid: 511. Strain: ifo 14479. Strain: ifo 14479

Chains: A, B, D, H (359 residues) CATH domain: 2.130.10.10

2oiz

Crystal structure of the tryptamine-derived (indol-3-acetamide)-ttq adduct of aromatic amine dehydrogenase

Source: Alcaligenes faecalis. Organism_taxid: 511. Organism_taxid: 511

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group TSR is 61.54% similar to enzyme product aromatic aldehyde

2ojy

Crystal structure of indol-3-acetaldehyde derived ttq-amide adduct of aromatic amine dehydrogenase

Source: Alcaligenes faecalis. Organism_taxid: 511. Organism_taxid: 511

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group TSR is 61.54% similar to enzyme product aromatic aldehyde

2ok4

Crystal structure of aromatic amine dehydrogenase ttq- phenylacetaldehyde adduct oxidized with ferricyanide

Source: Alcaligenes faecalis. Organism_taxid: 511. Organism_taxid: 511

Chains: D, H, A, B (110 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group HY1 is 88.89% similar to enzyme product aromatic aldehyde

2ok6

Crystal structure of aromatic amine dehydrogenase ttq-formamide adduct oxidized with ferricyanide.

Source: Alcaligenes faecalis. Organism_taxid: 511. Organism_taxid: 511

Chains: D, H, A, B (111 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group BEZ corresponds to enzyme product aromatic aldehyde

2q7q

Crystal structure of alcaligenes faecalis aadh in complex with p- chlorobenzylamine.

Source: Alcaligenes faecalis. Organism_taxid: 511. Gene: aaua. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: aaub. Expression_system_taxid: 562

Chains: D, H, A, B (109 residues) CATH domain: 2.60.30.10

Bound ligand: Het Group C2B is 70.00% similar to enzyme product aromatic aldehyde