_EC 1.21.99.5 tetrachloroethene reductive dehalogenase. 6 PDB entries  
EC 1.-.-.- Oxidoreductases. [21,435 PDB entries]
EC 1.21.-.- Catalyzing the reaction X-H + Y-H = 'X-Y'. [120 PDB entries]
EC 1.21.99.- With other acceptors. [9 PDB entries]
EC 1.21.99.5 tetrachloroethene reductive dehalogenase. [6 PDB entries]
5m2g

Reaction: trichloroethene + chloride + A + H(+) = tetrachloroethene + AH2.
 


trichloroethene
+ chloride
+
+ H(+)
=
tetrachloroethene
+ AH2
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): tetrachloroethene reductase.
Comments: This enzyme allows the common pollutant tetrachloroethene to support bacterial growth and is responsible for disposal of a number of chlorinated hydrocarbons by this organism. The reaction occurs in the reverse direction. The enzyme also reduces trichloroethene to dichloroethene. Although the physiological reductant is unknown, the supply of reductant in some organisms is via reduced menaquinone, itself formed from molecular hydrogen, via Ec 1.12.5.1. Methylviologen can act as electron donor. Formerly Ec 1.97.1.8.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 6 PDB entries in enzyme class E.C.1.21.99.5

  PDB code Protein
5m2g
Pce reductive dehalogenase from s. Multivorans in complex with 2,4,6- tribromophenol
Source: Sulfurospirillum multivorans. Organism_taxid: 66821
Chains: A, B (445 residues)
5m8u
Pce reductive dehalogenase from s. Multivorans in complex with 4- bromophenol
Source: Sulfurospirillum multivorans. Organism_taxid: 66821
Chains: A, B (444 residues)
5m8w
Pce reductive dehalogenase from s. Multivorans in complex with 4- chlorophenol
Source: Sulfurospirillum multivorans. Organism_taxid: 66821
Chains: A, B (443 residues)
5ma2
Pce reductive dehalogenase from s. Multivorans in complex with 4- iodophenol
Source: Sulfurospirillum multivorans. Organism_taxid: 66821
Chains: A, B (445 residues)
5obp
Pce reductive dehalogenase from s. Multivorans with 6- hydroxybenzimidazolyl norcobamide cofactor
Source: Sulfurospirillum multivorans. Organism_taxid: 66821
Chains: A, B (444 residues)
8q4h
A membrane-bound menaquinol:organohalide oxidoreductase complex rdh complex
Source: Desulfitobacterium hafniense tce1. Organism_taxid: 884048. Organism_taxid: 884048
Chains: A, B (503 residues)