_EC 1.2.1.85 2-hydroxymuconate-6-semialdehyde dehydrogenase.

0 PDB entries

EC 1.-.-.- Oxidoreductases. [21,484 PDB entries] EC 1.2.-.- Acting on the aldehyde or oxo group of donors. [1,276 PDB entries] EC 1.2.1.- With NAD(+) or NADP(+) as acceptor. [958 PDB entries] EC 1.2.1.85 2-hydroxymuconate-6-semialdehyde dehydrogenase. [-]

Reaction:		(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + NAD(+) + H2O = (2Z,4E)-2- hydroxyhexa-2,4-dienedioate + Nadh + 2 H(+).
		(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + NAD(+) + H2O = (2Z,4E)-2- hydroxyhexa-2,4-dienedioate + NADH + 2 × H(+) Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments:		This substrate for this enzyme is formed by meta ring cleavage of catechol (EC 1.13.11.2), and is an intermediate in the bacterial degradation of several aromatic compounds. Has lower activity with benzaldehyde. Activity with NAD(+) is more than 10-fold higher than with NADP(+). cf. Ec 1.2.1.32.
Links:		[IntEnz]   [ExPASy]   [KEGG]

There are no PDB entries in enzyme class E.C.1.2.1.85