_EC 1.14.14.179 brassinosteroid 6-oxygenase. 0 PDB entries  
EC 1.-.-.- Oxidoreductases. [21,435 PDB entries]
EC 1.14.-.- Acting on paired donors, with incorporation or reduction of molecu [4,709 PDB entries]
EC 1.14.14.- With reduced flavin or flavoprotein as one donor, and incorporati [1,155 PDB entries]
EC 1.14.14.179 brassinosteroid 6-oxygenase. [-]

Reaction: 6-deoxocastasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = castasterone + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+).
 


6-deoxocastasterone
+ 2 × reduced [NADPH--hemoprotein reductase]
+
2 × O2
=
castasterone
+ 2 × oxidized [NADPH--hemoprotein reductase]
+ 3 × H2O
+ 2 × H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): brassinosteroid 6-oxidase. CYP85A1. CYP85A2.
Comments: This cytochrome P450 (heme thiolate) plant enzyme catalyzes the C-6 hydoxylation of several brassinosteroid biosynthesis intermediates, and the further oxidation of the hydroxyl group to an oxo group. Substrates include 6-deoxocastasterone, 6-deoxotyphasterol, 3-dehydro-6-deoxoteasterone, and 6-deoxoteasterone. The CYP85A2 isozyme of Arabidopsis thaliana (but not the CYP85A1 isozyme) also catalyzes the activity of Ec 1.14.14.180.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.1.14.14.179