_EC 1.12.7.2 ferredoxin hydrogenase.

54 PDB entries

EC 1.-.-.- Oxidoreductases. [21,491 PDB entries] EC 1.12.-.- Acting on hydrogen as donors. [251 PDB entries] EC 1.12.7.- With an iron-sulfur protein as acceptor. [54 PDB entries] EC 1.12.7.2 ferredoxin hydrogenase. [54 PDB entries]

1c4a

Reaction:		H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+).
Other name(s):		bidirectional hydrogenase. H2 oxidizing hydrogenase. H2 producing hydrogenase. hydrogenase. hydrogenase (ferredoxin). hydrogenase I. hydrogenase Ii. hydrogenlyase. hydrogen-lyase. uptake hydrogenase.
Comments:		Can use molecular hydrogen for the reduction of a variety of substances. Formerly Ec 1.12.1.1, Ec 1.12.7.1, Ec 1.18.3.1, Ec 1.18.99.1 and Ec 1.98.1.1.
Links:		[IntEnz]   [ExPASy]   [KEGG]

There are 54 PDB entries in enzyme class E.C.1.12.7.2

PDB code		Protein
1c4a		Binding of exogenously added carbon monoxide at the active site of the fe-only hydrogenase (cpi) from clostridium pasteurianum Source: Clostridium pasteurianum. Organism_taxid: 1501. Cellular_location: cytoplasm Chain: A (574 residues) CATH domains: 3.10.20.740 3.30.70.20
1c4c		Binding of exogenously added carbon monoxide at the active site of the fe-only hydrogenase (cpi) from clostridium pasteurianum Source: Clostridium pasteurianum. Organism_taxid: 1501. Cellular_location: cytoplasm Chain: A (574 residues) CATH domains: 3.10.20.740 3.30.70.20
1e08		Structural model of the [fe]-hydrogenase/cytochrome c553 complex combining nmr and soft-docking Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Atcc: 7757. Cellular_location: periplasm. Desulfovibrio vulgaris. Organism_taxid: 882. Strain: hildenborough. Cellular_location: periplasm Chains: A, D (371 residues)
1feh		Fe-only hydrogenase from clostridium pasteurianum Source: Clostridium pasteurianum. Organism_taxid: 1501 Chain: A (574 residues) CATH domains: 3.10.20.740 3.30.70.20
1gx7		Best model of the electron transfer complex between cytochrome c3 and [fe]-hydrogenase Source: Desulfovibrio vulgaris. Organism_taxid: 882. Strain: hildenborough. Strain: hildenborough Chains: A, D (371 residues)
1hfe		1.6 a resolution structure of the fe-only hydrogenase from desulfovibrio desulfuricans Source: Desulfovibrio vulgaris subsp. Vulgaris str. Hildenborough. Organism_taxid: 882. Strain: hildenborough / atcc 29579 / ncimb 8303. Atcc: 7757. Cellular_location: periplasm. Cellular_location: periplasm Chains: S, L, T, M (88 residues) CATH domain: 4.10.260.20
3c8y		1.39 angstrom crystal structure of fe-only hydrogenase Source: Clostridium pasteurianum Chain: A (574 residues) CATH domains: 3.10.20.740 3.30.70.20
4xdc		Active semisynthetic [fefe]-hydrogenase cpi with aza-dithiolato- bridged [2fe] cofactor Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli. Expression_system_taxid: 562 Chains: A, B (581 residues) CATH domains: 3.10.20.740 3.30.70.20
4xdd		Apo [fefe]-hydrogenase cpi Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli. Expression_system_taxid: 562 Chains: A, B (582 residues) CATH domains: 3.10.20.740 3.30.70.20
5byq		Semisynthetic [fefe]-hydrogenase cpi with oxodithiolato-bridged [2fe] cofactor Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (580 residues) CATH domains: 3.10.20.740 3.30.70.20
5byr		Semisynthetic [fefe]-hydrogenase cpi with propane-dithiolato-bridged [2fe] cofactor Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (571 residues) CATH domains: 3.10.20.740 3.30.70.20
5bys		Semisynthetic [fefe]-hydrogenase cpi with sulfur-dithiolato-bridged [2fe] cofactor Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (576 residues) CATH domains: 3.10.20.740 3.30.70.20
5la3		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant e279a Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (574 residues)
5oef		Active semisynthetic [fefe]-hydrogenase cpi with aza-diselenato- bridged [2fe] cofactor Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr Chains: A, B (574 residues)
6cfw		Cryoem structure of a respiratory membrane-bound hydrogenase Source: Pyrococcus furiosus com1. Organism_taxid: 1185654. Gene: pfc_06375. Expressed in: pyrococcus furiosus. Expression_system_taxid: 2261. Gene: pfc_06370. Pyrococcus furiosus (strain atcc 43587 / dsm 3638 / jcm 8422 / vc1). Organism_taxid: 186497. Chains: J, K, L (143 residues)
6gly		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant c299a Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (580 residues)
6glz		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant c299d Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (579 residues)
6gm0		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant e279q Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (579 residues)
6gm1		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant e282a Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (575 residues)
6gm2		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant e282d Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (578 residues)
6gm3		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant r286a Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (574 residues)
6gm4		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant s319a Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (575 residues)
6gm8		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant e282q Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (579 residues)
6h63		Semisynthetic [fefe]-hydrogenase cpi with ethanedithiolate [2fe] cofactor Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: discr. Chains: A, B (578 residues)
6n59		1.0 angstrom crystal structure of [fefe]-hydrogenase Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: clostridium pasteurianum. Expression_system_taxid: 1501 Chain: A (571 residues)
6n6p		Crystal structure of [fefe]-hydrogenase in the presence of 7 mm sodium dithionite Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: clostridium pasteurianum. Expression_system_taxid: 1501 Chain: A (574 residues)
6nac		Crystal structure of [fefe]-hydrogenase i (cpi) solved with single pulse free electron laser data Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: clostridium pasteurianum. Expression_system_taxid: 1501 Chain: A (573 residues)
6yf4		[Fefe]-hydrogenase i from clostridium pasteurianum (cpi), variant e279d Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: delta-iscr Chains: A, B (580 residues)
7q4v		Electron bifurcating hydrogenase - hydabc from a. Woodii Source: Acetobacterium woodii dsm 1030. Organism_taxid: 931626. Organism_taxid: 931626 Chains: A, B, C, E, F, G (583 residues)
7q4w		Cryoem structure of electron bifurcating fe-fe hydrogenase hydabc complex a. Woodii in the oxidised state Source: Acetobacterium woodii dsm 1030. Organism_taxid: 931626. Strain: atcc 29683 / dsm 1030 / jcm 2381 / kctc 1655 / wb1. Organism_taxid: 931626 Chains: A, B, C, E, F, G (583 residues)
7qhf		[Fefe]-hydrogenase i from clostridium pasteurianum (cpi), variant g302s Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (579 residues)
7qv7		Cryo-em structure of hydrogen-dependent co2 reductase. Source: Thermoanaerobacter kivui. Organism_taxid: 2325. Organism_taxid: 2325 Chains: D, K, Q, R, V, Z (448 residues)
8a5e		Cryo-em structure of the electron bifurcating fe-fe hydrogenase hydabc complex from acetobacterium woodii in the reduced state Source: Acetobacterium woodii dsm 1030. Organism_taxid: 931626. Organism_taxid: 931626 Chains: A, B, C, D (583 residues)
8aio		Co-bound [fefe]-hydrogenase i from clostridium pasteurianum (cpi) Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (573 residues)
8aj6		Cyanide-bound [fefe]-hydrogenase i from clostridium pasteurianum (cpi) Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (580 residues)
8aln		Co-bound [fefe]-hydrogenase i from clostridium pasteurianum (cpi) at 1.34 angstrom Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (581 residues)
8ap2		Cyanide-bound [fefe]-hydrogenase i from clostridium pasteurianum (cpi) at 1.39 angstrom Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (581 residues)
8bj7		Desulfovibrio desulfuricans fefe hydrogenase c178a mutant in hinact- like state Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Strain: atcc 29579 / dsm 644 / ncimb 8303 / vkm b-1760 / hildenborough. Gene: hyda, dvu_1769. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hydb, dvu_1770. Expression_system_taxid: 562 Chains: A, B (395 residues)
8bj8		Desulfovibrio desulfuricans fefe hydrogenase c178a mutant in htrans- like state Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hydb, dvu_1770. Expression_system_taxid: 562 Chains: A, B (394 residues)
8cjy		[Fefe]-hydrogenase cpi from clostridium pasteurianum, variant s357t Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (580 residues)
8pvm		Formaldehyde-inhibited [fefe]-hydrogenase cpi from clostridium pasteurianum, variant c299d Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (573 residues)
8qm3		Formaldehyde-inhibited [fefe]-hydrogenase i from clostridium pasteurianum (cpi) Source: Clostridium pasteurianum. Organism_taxid: 1501. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008 Chains: A, B (574 residues)
8rtg		Desulfovibrio desulfuricans [fefe] hydrogenase in apo form Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr. Gene: hydb, dvu_1770. Expression_system_variant: (delta)iscr Chains: A, B (400 residues)
8rti		Desulfovibrio desulfuricans [fefe] hydrogenase in the apo form derivatized with krypton Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr. Gene: hydb, dvu_1770. Expression_system_variant: (delta)iscr Chains: A, B (393 residues)
8ru6		Desulfovibrio desulfuricans [fefe]-hydrogenase variant with both subunits linked by a 4 amino acid linker peptide derived from cpi of clostridium pasteurianum Source: Desulfovibrio desulfuricans, clostridium pasteurianum. Organism_taxid: 876, 1501. Gene: hyda, dvu_1769, hydb, dvu_1770. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Chain: B (484 residues)
8ru7		Desulfovibrio desulfuricans [fefe]-hydrogenase variant with both subunits linked by a 13 amino acid linker peptide derived from cpi of clostridium pasteurianum Source: Desulfovibrio desulfuricans, clostridium pasteurianum. Organism_taxid: 876, 1501. Gene: hyda, dvu_1769, hydb, dvu_1770. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr Chain: A (471 residues)
8rxi		Desulfovibrio desulfuricans [fefe] hydrogenase in hinact state derivatized with krypton Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr. Gene: hydb, dvu_1770. Expression_system_variant: (delta)iscr Chains: A, B (393 residues)
8rxj		Desulfovibrio desulfuricans [fefe] hydrogenase c178a mutant in hinact- like state derivatized with krypton Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr. Gene: hydb, dvu_1770. Expression_system_variant: (delta)iscr Chains: A, B (394 residues)
8ryh		Desulfovibrio desulfuricans [fefe]-hydrogenase variant with both subunits linked by a linker peptide derived from a group a1 type [fefe]-hydrogenase of veillonella atypica Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769, hydb, dvu_1770. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr Chain: A (469 residues)
9gbu		Desulfovibrio desulfuricans [fefe]-hydrogenase variant with both subunits linked by a 13 amino acid linker peptide derived from a group a1 type [fefe]-hydrogenase of solobacterium moorei Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769, hydb, dvu_1770. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr Chains: A, B (478 residues)
9gnk		Desulfovibrio desulfuricans [fefe]-hydrogenase variant with both subunits linked by a 13 amino acid linker peptide derived from cpi of clostridium pasteurianum Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769, hydb, dvu_1770. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: (delta)iscr Chain: A (485 residues)
9gz0		Fefe hydrogenase from desulfovibrio desulfuricans labelled with cyanophenylalanine - oxidised state Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hydb, dvu_1770. Expression_system_taxid: 562 Chains: A, B (394 residues)
9gz4		Fefe hydrogenase from desulfovibrio desulfuricans labelled with cyanophenylalanine - reduced state Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hydb, dvu_1770. Expression_system_taxid: 562 Chains: A, B (394 residues)
9gzl		Apo fefe hydrogenase from desulfovibrio desulfuricans labelled with cyanophenylalanine Source: Desulfovibrio desulfuricans. Organism_taxid: 876. Gene: hyda, dvu_1769. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hydb, dvu_1770. Expression_system_taxid: 562 Chains: A, B (395 residues)