_EC 1.11.1.28 lipoyl-dependent peroxiredoxin.

6 PDB entries

EC 1.-.-.- Oxidoreductases. [21,484 PDB entries] EC 1.11.-.- Acting on a peroxide as acceptor. [1,313 PDB entries] EC 1.11.1.- Peroxidases. [1,209 PDB entries] EC 1.11.1.28 lipoyl-dependent peroxiredoxin. [6 PDB entries]

1gu9

Reaction:		N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O.
		N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + alcohol + H2O Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments:		Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant proteins. They can be divided into three classes: typical 2-Cys, atypical 2-Cys and 1-Cys peroxiredoxins. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. All three peroxiredoxin classes have the first step in common, in which the peroxidatic cysteine attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step of the peroxidase reaction, the regeneration of
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There are 6 PDB entries in enzyme class E.C.1.11.1.28

PDB code		Protein
1gu9		Crystal structure of mycobacterium tuberculosis alkylperoxidase ahpd Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 27294. Expressed in: escherichia coli. Expression_system_taxid: 562 Chains: A, B, C, D, E, F, G, H, I, J, K, L (172 residues) CATH domain: 1.20.1290.10
1knc		Structure of ahpd from mycobacterium tuberculosis, a novel enzyme with thioredoxin-like activity. Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Expressed in: escherichia coli. Expression_system_taxid: 562 Chains: A, B, C (174 residues) CATH domain: 1.20.1290.10
1lw1		Crystal structure of mycobacterium tuberculosis alkylperoxidase ahpd h137f mutant Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Chains: A, B, C (175 residues) CATH domain: 1.20.1290.10
1me5		Crystal structure of mycobacterium tuberculosis alkylperoxidase ahpd h132q mutant Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Expressed in: escherichia coli. Expression_system_taxid: 562. Chains: A, B, C (173 residues) CATH domain: 1.20.1290.10
2bmx		Mycobacterium tuberculosis ahpc Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli. Expression_system_taxid: 511693. Chains: A, B, C (169 residues) CATH domain: 3.40.30.10
7bz6		Mycobacterium bovis ahpc Source: Mycobacterium bovis. Organism_taxid: 1765. Gene: ahpc. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Chains: A, B (170 residues)