The enzyme catalyzes catalyses the Mg(2+)-dependent reversible cleavage ofisocitrate into succinate and glyoxylate (PMID10801489).
MG 451 A IN THE RESTING STATE ENZYME
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Representative PDB structure for MG 451 A in the resting state enzyme | |
| PDB code | 1f61 | |
| Metal Type in the PDB | magnesium | |
| Residue name of the metal in the PDB | MG | |
| Residue number of the metal in the PDB | 451 | |
| Chain of the metal in the PDB | A | |
| Atom name of the metal in the PDB | MG | |
| Download the coordinates file of the metal site | NOTES ON PDB: | |
| First Coordination Sphere | ||||||
| Ligand Type | Ligand Identity | Residue In MACiE | Donors | Bind Mode | Catalytic? | Notes |
| residue | ASP 108 A | ASP 108 A | OD1,OD2 | bidentate | No | - |
| residue | GLU 155 A | GLU 155 A | OE1 | monodentate | No | - |
| water | HOH 575 A | - | O | monodentate | No | - |
| water | HOH 690 A | - | O | monodentate | No | - |
| water | HOH 699 A | - | O | monodentate | No | - |