The enzyme catalyse the hydrolysis of dipeptides. It is an homodimer and each subunit binds two zinc ions in a dinuclear site (PMID12144777)
ZN 401 A IN THE RESTING STATE ENZYME
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Representative PDB structure for ZN 401 A in the resting state enzyme | |
|   | ||
| PDB code | 1itq | |
| Metal Type in the PDB | zinc | |
| Residue name of the metal in the PDB | ZN | |
| Residue number of the metal in the PDB | 401 | |
| Chain of the metal in the PDB | A | |
| Atom name of the metal in the PDB | ZN | |
| Download the coordinates file of the metal site | NOTES ON PDB: | |
| First Coordination Sphere | ||||||
| Ligand Type | Ligand Identity | Residue In MACiE | Donors | Bind Mode | Catalytic? | Notes |
| residue | HIS 20 A | HIS 20 A | NE2 | monodentate | No | - |
| residue | ASP 22 A | ASP 22 A | OD1 | monodentate | No | - |
| residue | GLU 125 A | GLU 125 A | OE1 | monodentate | No | - |
| water | HOH 421 _ | - | O | monodentate | No | - |
| water | HOH 422 _ | - | O | monodentate | No | - |





