CATALYTIC METAL(S)

Metal/Site Information
Residue in MACiE* Atom in MACiE* Residue Type in MACiE Physiological
Metal		 Site
Type		 Function(s)
MG 156 AMG magnesium magnesium mononuclear Coordinates substrate
Electrostatic stabiliser
Increases electrophilicity

*It refers to the MACiE reference pdb: 1kdn

Metal/s Properties in Resting State
MG 156 A Resting state enzyme (-)
Oxidation State 2
Coordination Geometry unknownGeometry
Coordination Number unknown
Notes -


References
-Gallois-Montbrun S, Chen Y, Dutartre H, Sophys M, Morera S, Guerreiro C, Schneider B, Mulard L, Janin J, Veron M, Deville-Bonne D, Canard B
Structural analysis of the activation of ribavirin analogs by NDP kinase: comparison with other ribavirin targets.
Mol Pharmacol. 2003 Mar;63(3):538-46.(MEDLINE:12606760)
-Hutter MC, Helms V
The mechanism of phosphorylation of natural nucleosides and anti-HIV analogues by nucleoside diphosphate kinase is independent of their sugar substituents.
Chembiochem. 2002 Jul 2;3(7):643-51.(MEDLINE:12324998)