The enzyme catalyzes the convertion of a broad spectrum of aldose sugars into the corresponding lactones which are hydrolyzed to the aldonic acids. It is a dimer and each subunit binds three calcium ions: two involved in dimerization of the subunits, one involved in the catalytic reaction (PMID12686124).
CA 1003 A IN THE RESTING STATE ENZYME
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Representative PDB structure for CA 1003 A in the resting state enzyme | |
| PDB code | 1qbi | |
| Metal Type in the PDB | calcium | |
| Residue name of the metal in the PDB | CA | |
| Residue number of the metal in the PDB | 467 | |
| Chain of the metal in the PDB | _ | |
| Atom name of the metal in the PDB | CA | |
| Download the coordinates file of the metal site | NOTES ON PDB: | |
| First Coordination Sphere | ||||||
| Ligand Type | Ligand Identity | Residue In MACiE | Donors | Bind Mode | Catalytic? | Notes |
| residue | GLY 247 B | GLY 247 A | O | monodentate | No | - |
| residue | PRO 248 B | PRO 248 A | O | monodentate | No | - |
| water | HOH 140 _ | - | O | monodentate | No | - |
| water | HOH 220 _ | - | O | monodentate | No | - |
| water | HOH 265 _ | - | O | monodentate | No | - |