Introduction
Sequence Similarity Search (SSS) is a method of searching sequence databases by using alignment to a query sequence. By statistically assessing how well database and query sequences match one can infer homology and transfer information to the query sequence.
Important Note
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| REST Service | Description |
|---|---|
| FASTA | Fast protein or nucleotide comparison using the FASTA suite. Includes Smith and Waterman local-local (SSEARCH), global-local (GLSEARCH) and global-global (GGSEARCH) alignment searches. |
| FASTM | Peptide fragment searches using the FASTF, FASTM or FASTS programs from the FASTA suite. |
| NCBI BLAST+ | Compare a sequence with those contained in nucleotide and protein databases using NCBI BLAST. |
| PSI-BLAST | Position Specific Iterative BLAST (PSI-BLAST), guided mode |
| PSI-Search | Iterative Smith and Waterman using a PSI-BLAST strategy |