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2046 Search results for search term human

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Murine RPE proteome and phosphoproteome
Species: Mus musculus (Mouse)
Project description: pathogenesis of multiple human retinal degenerative disorders, including age-related macular degeneration (AMD (More)
Made public: 2017-10-27
ARPE19 proteome and phosphoproteome
Species: Homo sapiens (Human)
Project description: pathogenesis of multiple human retinal degenerative disorders, including age-related macular degeneration (AMD (More)
Made public: 2017-10-27
cultured RPE phosphpproteome
Species: Mus musculus (Mouse)
Project description: pathogenesis of multiple human retinal degenerative disorders, including age-related macular degeneration (AMD (More)
Made public: 2017-10-27
Endogenous androgen receptor proteomic profiling reveals genomic subcomplex involved in prostate tumorigenesis
Species: Homo sapiens (Human)
Project description: Androgen receptor (AR) is a key player in prostate cancer develo (More)
Made public: 2017-10-27
LC-MS/MS analysis of Daoy and UW228 medulloblastoma cell lines
Species: Homo sapiens (Human)
Project description: The goal of this study was to profile the total proteome and tra (More)
Made public: 2017-10-27
Optimization of Experimental Parameters in Data-Independent Mass Spectrometry Significantly Increases Depth and Reproducibility of Results
Species: Homo sapiens (Human)
Project description: -independent acquisition, we identified and quantified 6,383 proteins in human cell lines using 2-or-more (More)
Made public: 2017-10-27
Proteomic and Clinical Analysis of a Fine-needle Aspirate Biopsy from a Single Cold Thyroid Nodule: A Case Study
Species: Homo sapiens (Human)
Project description: Purpose: To clinically and proteomically profile a fine-needle a (More)
Made public: 2017-10-26
Quantitative label-free proteomic analysis of human urine to identify novel protein biomarkers for schistosomiasis
Species: Homo sapiens (Human)
Project description: -throughput proteomic approach was used to analyse human urine samples for 49 volunteers from Eggua, a (More)
Made public: 2017-10-24
An Informatic Approach to Chimeric Antigen Receptor Discovery Integrates Proteomics and Transcriptomics to Identify Novel Combinatorial Pairs
Species: Homo sapiens (Human)
Project description: Chimeric antigen receptor (CAR) therapy targeting CD19 yielded r (More)
Made public: 2017-10-24
A glucagon variant, glucagon 1-61, identified in man, controls blood glucose through regulation of insulin secretion and hepatic glucose production
Species: Homo sapiens (Human)
Project description: human plasma by high-resolution-proteomics, we identified several glucagon variants among which (More)
Made public: 2017-10-20
TAILS N-terminomics of the human dental pulp stroma and the odontoblast layer
Species: Homo sapiens (Human)
Project description: We report the targeted analysis of the human dental pulp stroma and the odontoblast layer using the (More)
Made public: 2017-10-20
PROTEOLYTIC SIGNATURES OF THROMBIN-DERIVED PEPTIDES by LC-MS/MS
Species: Homo sapiens (Human)
Project description: We hypothesized that the peptide profile could reflect the actio (More)
Made public: 2017-10-20
Prediction of protein complexes in Trypanosoma brucei by protein correlation profiling mass spectrometry and machine learning
Species: Trypanosoma brucei
Project description: Trypanosoma brucei, an important human and animal pathogen, are hypothetical proteins of unknown function (More)
Made public: 2017-10-20
Endogenous brain ARC complexes
Species: Mus musculus (Mouse)
Project description: , assembly into multiprotein complexes, role in human disease and cognition. We applied an integrated (More)
Made public: 2017-10-19
Comparison of Intact Glycopeptide Enrichment Methods Using Strong Anion Exchange and Hydrophilic Interaction Liquid Chromatography
Species: Homo sapiens (Human)
Project description: Heterogeneity of protein glycosylation poses great challenge for (More)
Made public: 2017-10-19
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Species: Homo sapiens (Human)
Project description: TRIM25 is a novel RNA-binding protein and a member of the Tripar (More)
Made public: 2017-10-19
A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis
Species: Homo sapiens (Human)
Project description: characterise commitment by integrating transcriptomic and proteomic data from disaggregated primary human (More)
Made public: 2017-10-18
Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS
Species: Homo sapiens (Human)
Project description: and phosphorylation changes in interphase and mitotic fractions from asynchronously growing human (More)
Made public: 2017-10-18
LC-MS/MS of the secreted fraction of Shigella
Species: Shigella flexneri
Project description: Many human Gram-negative bacterial pathogens express a Type Three Secretion Apparatus (T3SA (More)
Made public: 2017-10-17
He Xiang - BfrB
Species: Homo sapiens (Human)
Project description: To identify the macrophage binding partner of Mtb BfrB, we selec (More)
Made public: 2017-10-17
Mtb BfrB interacted proteins
Species: Homo sapiens (Human)
Project description: MS.We identified that Mtb BfrB interact with human RPS3. (More)
Made public: 2017-10-17
RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1
Species: Homo sapiens (Human)
Project description: Notch signaling is an evolutionarily conserved signal transducti (More)
Made public: 2017-10-17
Biotinylation by antibody recognition - A novel method for proximity labeling
Species: Homo sapiens (Human)
Project description: Identification of protein-protein interactions is a major goal o (More)
Made public: 2017-10-17
Improved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides
Species: Homo sapiens (Human)
Project description: isolation and identification. These changes have led to the detection of several new human SEPs (novel human (More)
Made public: 2017-10-17
KCC2 Proteome
Species: Mus musculus (Mouse)
Project description: spine morphogenesis and AMPA receptor confinement. Aberrant KCC2 function contributes to numerous human (More)
Made public: 2017-10-16
Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging: a novel Tool for the Identification and Classification of Amyloidosis
Species: Homo sapiens (Human)
Project description: Amyloidosis is a group of diseases caused by extracellular accum (More)
Made public: 2017-10-16
Differential kinobeads selectivity profiling
Species: Homo sapiens (Human)
Project description: The goal of this project was to use differential kinobeads profi (More)
Made public: 2017-10-13
Identification of the covalent binding site of Ibrutinib and 5Z-7-Oxozeaenol to ZAK
Species: Homo sapiens (Human)
Project description: The goal of this experiment was to identify the reaction site of (More)
Made public: 2017-10-13
Confirmation of ZAK as covalent target of Ibrutinib
Species: Homo sapiens (Human)
Project description: The goal of this experiment was the confirmation of ZAK as a cov (More)
Made public: 2017-10-13
Human Salivary Cystatins
Species: Homo sapiens (Human)
Project description: by bottom-up strategies in the acidic soluble fraction of human saliva. The several proteoforms (More)
Made public: 2017-10-13
Multiplexed thiol reactivity profiling for target discovery of electrophilic natural products
Species: Homo sapiens (Human)
Project description: Electrophilic groups, such as Michael acceptors, expoxides, are (More)
Made public: 2017-10-12
Identification and Characterization of MCM3 as a KEAP1 Substrate
Species: Homo sapiens (Human)
Project description: , few other KEAP1 substrates have been identified. Because KEAP1 is altered in a number of human (More)
Made public: 2017-10-12
Plasma membrane-derived extracellular microvesicles mediate non-canonical intercellular NOTCH signaling
Species: Homo sapiens (Human)
Project description: ARMMs (arrestin domain-containing protein 1 [ARRDC1]-mediated mi (More)
Made public: 2017-10-11
HLA-DRB1*15:01 and HLA-DRB5*01:01 peptidomes
Species: Homo sapiens (Human)
Project description: HLA-DR15 is a haplotype associated with multiple sclerosis. It c (More)
Made public: 2017-10-10
SIL1 deficiency in lymphoblastoid cells: antagonizing cellular mechanisms and insights into selective vulnerability in Marinesco-Sjögren syndrome
Species: Homo sapiens (Human)
Project description: Patients with Marinesco-Sjögren syndrome and gene targeting in m (More)
Made public: 2017-10-10
phospho HMMR Co-Immunoprecipitation
Species: Homo sapiens (Human)
Project description: Phosphorylated HMMR was immunoprecipitated from syncronized M or (More)
Made public: 2017-10-09
Optimising sample preparation of the plasma peptidome
Species: Homo sapiens (Human)
Project description: We further expanded on previous optimizations to isolate the pla (More)
Made public: 2017-10-09
Human Testis LC-MS/MS
Species: Homo sapiens (Human)
Project description: Missing proteins(MPs) investigation is one of the critical missions of Chromosome-based Human (More)
Made public: 2017-10-09
Proteomics Reveal Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress
Species: Homo sapiens (Human)
Project description: The mechanisms that protect eukaryotic DNA duringdepend on sever (More)
Made public: 2017-10-09
Immune repertoire after immunization as seen by next generation sequencing and proteomics
Species: Rattus norvegicus (Rat)
Project description: were immunized with dinitrophenol modified KLH or with recombinant human HuD. In the immune repertoire (More)
Made public: 2017-10-04
MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter
Species: Homo sapiens (Human)
Project description: Most E2F-binding sites repress transcription through the recruit (More)
Made public: 2017-10-04
Identifying host factors associated with DNA replicated during virus infection
Species: Homo sapiens (Human) Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Project description: Viral DNA genomes replicating in cells encounter a myriad of hos (More)
Made public: 2017-10-04
Human placenta tissue LC-MS
Species: Homo sapiens (Human)
Project description: We extracted DIP from placanta tissue of human which were diagnose preeclampsia or normal. The (More)
Made public: 2017-10-04
Breast Cancer Metastasis Organotropism
Species: Homo sapiens (Human)
Project description: Mass-spectrum profiling of secretory proteins of breast cancer c (More)
Made public: 2017-10-04
Thyroid-associated orbitopathy and tears: a proteomics study
Species: Homo sapiens (Human)
Project description: Thyroid-Associated Orbitopathy (TAO) is an autoimmune inflammato (More)
Made public: 2017-10-04
Metabolic reconstruction of lipid metabolism of Malassezia
Species: Malassezia furfur Malassezia sympodialis Malassezia pachydermatis Malassezia globosa
Project description: Malassezia species are lipophilic and lipid dependent yeasts belonging to the human and animal (More)
Made public: 2017-10-02
Human bladder,colon,kidney,liver cancer LC MS/MS
Species: Homo sapiens (Human)
Project description: MPs with 73 unique peptides were identified from four human tissues, including 10 membrane proteins (More)
Made public: 2017-10-02
Synaptosomal proteome from schizophrenia patients
Species: Homo sapiens (Human)
Project description: Proteomic characterization of the synaptosome fraction of the or (More)
Made public: 2017-09-29
Identification of Siglec ligands in human B cell
Species: Homo sapiens (Human)
Project description: Siglecs are a family of receptor-type glycan recognition protein (More)
Made public: 2017-09-29
Converging SUMO and ubiquitin signaling: improved methodology identifies co-modified target proteins
Species: Homo sapiens (Human)
Project description: Post translational protein modifications (PTMs) including small (More)
Made public: 2017-09-29
Comprehensive identification of proteins expressed by human oligodendroglia cell line
Species: Homo sapiens (Human)
Project description: Oligodendrocytes are a type of neuroglia that have provide troph (More)
Made public: 2017-09-27
Non-pregnant CVF protome and peptidome
Species: Homo sapiens (Human)
Project description: Cervical-vaginal fluid (CVF) covers the lower part of the female (More)
Made public: 2017-09-27
Non-pregnant CVF peptidome
Species: Homo sapiens (Human)
Project description: Cervical-vaginal fluid (CVF) covers the lower part of the female (More)
Made public: 2017-09-27
Metabolite Perception Regulates Colonization and Virulence during Polymicrobial Infection
Species: Porphyromonas gingivalis ATCC 33277
Project description: Many human infections are polymicrobial in origin, and interactions among community inhabitants (More)
Made public: 2017-09-26
Chemical proteomics to elucidate target proteins of cysteine-stabilized and circular peptides
Species: Homo sapiens (Human)
Project description: Cyclotides are circular and cystine-rich peptides which are litt (More)
Made public: 2017-09-26
CEGS Proteomics
Species: Homo sapiens (Human)
Project description: -depth quantitative proteomic survey of regions of the postnatal human brain. We adopted a dual approach (More)
Made public: 2017-09-26
Mapping Protein Targets of Bioactive Small Molecules using Lipid-Based Chemical Proteomics
Species: Homo sapiens (Human)
Project description: small molecule-protein interactions in human cells to gain mechanistic understanding of bioactive (More)
Made public: 2017-09-26
Comparative glycoproteomics of embryonic stem cells identifies new players in ricin toxicity
Species: Homo sapiens (Human)
Project description: method to human and murine embryonic stem cells, we were able to nearly double the number of all (More)
Made public: 2017-09-25
Can half-marathon affect overall health? The yin-yang of sport
Species: Homo sapiens (Human)
Project description: Physical activity improves overall health and counteracts metabo (More)
Made public: 2017-09-25
Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins
Species: Homo sapiens (Human)
Project description: Ubiquilins (Ubqlns) are a family of ubiquitin receptors that pro (More)
Made public: 2017-09-25
Global Proteome Analysis of the NCI-60 Cell Line Panel, part 3
Species: Homo sapiens (Human)
Project description: genetic diversity of human cancers and has been extensively molecularly characterized. Here, we present a (More)
Made public: 2017-09-25
Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion
Species: Plasmodium falciparum
Project description: Our understanding of the key phosphorylation-dependent signalling pathways in the human malaria (More)
Made public: 2017-09-22
Unrestricted analysis of modifications in proteins exposed to metal-catalyzed oxidation
Species: Homo sapiens (Human)
Project description: Bovine serum albumin and human serum proteins subjected to metal ion-catalyzed oxidation were (More)
Made public: 2017-09-21
The nuclear receptor ERbeta engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading
Species: Homo sapiens (Human)
Project description: cooperating with ERβ in gene regulation, we identified AGO2 as a novel partner of ERβ in human BC cells. ERβ (More)
Made public: 2017-09-20
A linear diubiquitin-based probe for efficient and selective detection of the deubiquitinating enzyme OTULIN
Species: Homo sapiens (Human)
Project description: The methionine1 (M1)-specific deubiquitinase OTULIN acts as a ne (More)
Made public: 2017-09-19
A comprehensive, open-source platform for mass spectrometry based glycoproteomics data analysis
Species: Homo sapiens (Human)
Project description: and human plasma cryoprecipitate. The results show that the simultaneous consideration of peptide and (More)
Made public: 2017-09-19
Human acute myeloid leukemia (AML) cell line LFQ, comparison between doxycycline-inducible control shRNA and Pim2 shRNA
Species: Homo sapiens (Human)
Project description: . MOLM-14 is a human FLT3-ITD AML cell line that was transduced with control (scrambled) or anti-Pim2 (More)
Made public: 2017-09-18
Carcinoma-associated fibroblasts stimulate cancer cell invasion by mechanically remodeling the basement membrane
Species: Homo sapiens (Human)
Project description: The first step in metastasis is dissemination of tumor cells int (More)
Made public: 2017-09-18
Comparative degradomics of porcine and human wound exudates unravels biomarker candidates for assessment of wound healing progression in trauma patients
Species: Homo sapiens (Human)
Project description: Impaired cutaneous wound healing is a major complication in elde (More)
Made public: 2017-09-14
Scanning quadrupole DIA
Species: Homo sapiens (Human)
Project description: range, including plasma, human cell lines, and bacteria samples, discussed. In addition, its (More)
Made public: 2017-09-14
Delineating the Rb1 interactome data and its modulations during cell cycle progression.
Species: Homo sapiens (Human)
Project description: The retinoblastoma (Rb) protein is a potent tumor suppressor whi (More)
Made public: 2017-09-14
eIF1 modulates the recognition of sub-optimal translation start sites and steers gene expression control mediated by uORFs.
Species: Homo sapiens (Human)
Project description: Alternative translation initiation mechanisms such as leaky scan (More)
Made public: 2017-09-13
Proteome of Hypoxic Glioblastoma Cells
Species: Homo sapiens (Human)
Project description: Tumors are known for hypoxic microenvironment due to decreased h (More)
Made public: 2017-09-12
Proteomic analysis of skeletal muscle reveals estrogen as a key regulator of muscle signaling in women
Species: Homo sapiens (Human)
Project description: Women’s aging is characterized by menopausal loss of ovarian fun (More)
Made public: 2017-09-12
Integrated lysine acetylation stoichiometry and proteomics analysis in human cells
Species: Homo sapiens (Human)
Project description: acetylation in three human cell lines. We identified and determined the acetylation occupancy in about 1500 (More)
Made public: 2017-09-12
Mapping the spatial proteome of metastatic cells in colorectal cancer
Species: Homo sapiens (Human)
Project description: Here, we aimed to study metastasis mechanisms using spatial prot (More)
Made public: 2017-09-11
Proteomic signature of environmental oxygen tension modulation of human macrophage polarization and functions
Species: Homo sapiens (Human)
Project description: parameters. We designed this study to obtain a proteomic signature of various polarizations in human (More)
Made public: 2017-09-11
Label free quantitative mass spectrometry identifies platelet degranulation as an early event during platelet storage
Species: Homo sapiens (Human)
Project description: Shelf life of platelet concentrates (PCs) is limited to up to 7 (More)
Made public: 2017-09-11
Quantitative analysis of the proteome response to the histone deacetylase inhibitor (HDACi) Vorniostat in Niemann-Pick Type C1 disease
Species: Homo sapiens (Human)
Project description: Niemann-Pick type C (NPC) disease is an inherited, progressive n (More)
Made public: 2017-09-11
NleB host targets
Species: Homo sapiens (Human)
Project description: The inhibition of host innate immunity pathways is essential for (More)
Made public: 2017-09-11
uDPMs in AD+CVD
Species: Homo sapiens (Human)
Project description: In this study we have profiled the temporal lobe proteome of AD+ (More)
Made public: 2017-09-11
A new method for differential proteomic analysis utilizing native MS-electropherograms: a comparison between plasma and serum proteins by combining native PAGE, whole-gel slicing and quantitative LC-MS/MS
Species: Homo sapiens (Human)
Project description: human plasma and serum samples were used as test samples and separated on a native PAGE gel. Six lanes (More)
Made public: 2017-09-08
Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP
Species: Homo sapiens (Human)
Project description: We have identified the plant biflavonoid hinokiflavone as an inh (More)
Made public: 2017-09-07
Proteome analysis of hypoxic glioblastoma cells reveals sequential metabolic adaptation of one-carbon metabolic pathways
Species: Homo sapiens (Human)
Project description: Rapidly proliferating tumors are exposed to a hypoxic microenvir (More)
Made public: 2017-09-07
Comparative proteomics of plasmodesmata
Species: Arabidopsis thaliana (Mouse-ear cress)
Project description: Plants as multi cellular organisms are composed of various speci (More)
Made public: 2017-09-05
Proteomic and phosphoproteomics profiling of breast cancer cells with altered expression level of the protein phosphatase TRAP
Species: Homo sapiens (Human)
Project description: Tartrate-resistant acid phosphatase (TRAP/ACP5) is a metalloenzy (More)
Made public: 2017-09-04
Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
Species: Homo sapiens (Human)
Project description: analysing the process of human fibroblast adaptation to the lack of ATM. We identify profound rearrangement (More)
Made public: 2017-09-04
Extraordinary Diversity of Amyloid-beta Proteoforms in Human Alzheimer's Disease Brain
Species: Homo sapiens (Human)
Project description: modifications and sequence variants) present in human AD brain. We used high-resolution mass spectrometry to (More)
Made public: 2017-09-04
Mapping and Quantification of Brain Protein O-GlcNAcylation in Alzheimer’s Disease
Species: Homo sapiens (Human)
Project description: Comprehensive, quantitative proteomics analysis of protein O-GlcNAcylation in post-mortem human (More)
Made public: 2017-09-04
Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer
Species: Homo sapiens (Human)
Project description: Finding missing proteins (MPs) has been one of the critical missions of Chromosome-Centric Human (More)
Made public: 2017-09-01
RWPE-PC3 secretome
Species: Homo sapiens (Human)
Project description: Prostate cancer is the leading type of cancer diagnosed and the (More)
Made public: 2017-08-30
Quantitative phosphoproteomic analysis of acquired drug resistance to pazopanib and dasatinib
Species: Homo sapiens (Human)
Project description: Acquired drug resistance and tumour relapse impacts the majority (More)
Made public: 2017-08-30
Phosphoproteomic analysis of Bluetongue virus infection
Species: Homo sapiens (Human)
Project description: Bluetongue virus causes infections in wild and domesticated rumi (More)
Made public: 2017-08-29
Ncd regulation reveals a new mechanism for targeting proteins to the meiotic spindle in oocytes
Species: Drosophila melanogaster (Fruit fly)
Project description: Drosophila oocytes. A critical 14-3-3 target is the minus-end directed motor Ncd (human HSET; kinesin-14 (More)
Made public: 2017-08-29
A sensitive and cost-effective approach for tyrosine phosphoproteome analysis based on SH2 superbinder
Species: Homo sapiens (Human)
Project description: Albeit much less abundant than Ser/Thr phosphorylation (pSer/pTh (More)
Made public: 2017-08-29
Nitration of Tyrosines In Complement Factor H Domains Alters Its Immunological Activity and Mediates A Pathogenic Role In Age Related Macular Degeneration
Species: Homo sapiens (Human)
Project description: Nitrosative stress has been implicated in the pathogenesis of ag (More)
Made public: 2017-08-29
Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain
Species: Homo sapiens (Human)
Project description: known about the proteoforms present in human AD brain. We used high-resolution mass spectrometry to (More)
Made public: 2017-08-28
Proteome Profiling of Renal Cancer Tumor Tissue and Non-Affected Renal Tissue in Patients with Von Hippel-Lindau Disease Highlights Differential Regulation of Xaa-Pro Aminopeptidases-1 and -2 (XPNPEP-1 and -2)
Species: Homo sapiens (Human)
Project description: Patients with loss-of-function mutations of the von Hippel Linda (More)
Made public: 2017-08-28
Phosphoproteomic analysis of T cell receptor stimulation-induced changes in human primary CD4+CD25- T cells in the absence or presence of regulatory T cells.
Species: Homo sapiens (Human)
Project description: This is an addition to dataset PXD004291. This data were only us (More)
Made public: 2017-08-28
Phosphoproteomic analysis of T cell receptor stimulation-induced changes in human primary CD4+CD25- T cells in the absence or presence of regulatory T cells.
Species: Homo sapiens (Human)
Project description: Regulatory T cells (Tregs) suppress other immune cells and are indispensable for human health, yet (More)
Made public: 2017-08-28

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