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The proteome of normal human iris, ciliary body, retinal pigment epithelium, and choroid
Species: Homo sapiens (Human)
Project description: valuable resource for future investigations of the eye in health and disease. The mass spectrometry (More)
Diseases: disease free
Made public: 2016-02-04
rat, urine, LC-MS/MS
Species: Rattus norvegicus (Rat)
Project description: Two MUPs of rat urine, odorant-binding protein 3 (OBP3) and MUP1 (More)
Diseases: disease free
Made public: 2018-02-26
Data-Independent Proteome Analysis of ARPE-19 Cells
Species: Homo sapiens (Human)
Project description: We have performed a proteomics analysis of a human retinal pigme (More)
Diseases: disease free
Made public: 2018-04-26
Two independent proteomic approaches provide the most comprehensive analysis of the synovial fluid proteome in responders and non-responders to Autologous Chondrocyte Implantation
Species: Homo sapiens (Human)
Project description: Background: Results obtained from our previous study using a label-free quantitation (LF) proteomic (More)
Tissues: rheumatoid arthritis disease specific synovial fluid
Made public: 2018-05-03
Loss-of-function of ubiquitin ligase adaptor LZTR1 triggers human disease by dysregulating RAS ubiquitination
Species: Homo sapiens (Human)
Project description: triggering its dissociation from the membrane. Disease-associated LZTR1 mutations affect either the LZTR1 (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-11-04
Assessment of Label-Free Quantification in Discovery Proteomics and Impact of Technological Factors and Natural Variability of Protein Abundance
Species: Arabidopsis thaliana (Mouse-ear cress)
Project description: Proteome wide protein quantification has become facile in the last years supported by label-free (More)
Diseases: disease free
Quantification method: Label free
Made public: 2017-03-07
Identification of In Vivo HLA-DR-Presented Self-Peptides (T Cell Epitopes) in Synovial Tissue, Synovial Fluid and Peripheral Blood in Patients with Rheumatoid Arthritis or Lyme Arthritis
Species: Homo sapiens (Human)
Project description: the disease. (More)
Diseases: Lyme disease
Modifications: cysteinylation (disulfide with free L-cysteine)
Made public: 2016-10-13
A normative study of the synovial fluid proteome from healthy porcine knee joints
Species: Homo sapiens (Human) Sus scrofa domesticus (domestic pig)
Project description: Synovial fluid in an articulating joint contains proteins derive (More)
Tissues: rheumatoid arthritis disease specific synovial fluid
Quantification method: MS1 intensity based label-free quantification method
Made public: 2014-09-09
Different Binding Motifs of the Celiac Disease Associated HLA Molecules DQ2.5, DQ2.2 and DQ7.5 Revealed by Relative Quantitative Proteomics of Endogenous Peptide Repertoires
Species: Homo sapiens (Human)
Project description: leukocyte antigen (HLA)-DQ molecules DQ2.5, DQ2.2 and DQ7.5 display different risks for celiac disease (More)
Diseases: celiac disease
Quantification method: Label free
Made public: 2014-12-04
Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation duringactivated Bcellsapoptosis
Species: Mus musculus (Mouse)
Project description: Here, we decipher the molecular mechanisms bridging B cell activ (More)
Diseases: disease free
Quantification method: Label free
Made public: 2016-09-26
Large-scale phosphoproteome analysis in seedling leaves of Brachypodium distachyon L
Species: Brachypodium distachyon (Purple false brome) (Trachynia distachya)
Project description: In this study, we carried out the first large-scale phosphoprote (More)
Diseases: disease free
Quantification method: Label free
Made public: 2016-07-09
Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Removal
Species: Homo sapiens (Human)
Project description: Cytotoxicity of DNA-protein crosslinks (DPCs) is ascribed largel (More)
Diseases: disease free
Quantification method: Label free
Made public: 2016-10-06
Defining targets of the bacterial ADP-ribosyltransferase EspJ
Species: Homo sapiens (Human)
Project description: Tyrosine phosphorylation is key for signal transduction from exo (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-03-16
Orthogonal interactome profiling of RNF41
Species: Homo sapiens (Human)
Project description: Ring finger protein 41 (RNF41) is an E3 ubiquitin ligase involve (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-03-26
The Itgb3 Adhesome
Species: Mus musculus (Mouse)
Project description: Integrin β3 is seen as a key anti-angiogenic target for cancer t (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-05-23
Generation and Proteome Profiling of PBMC-originated, iPSCs-derived Corneal Endothelial Cells
Species: Homo sapiens (Human)
Project description: Corneal endothelial cells (CECs) are critical to maintaining cla (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-06-06
RNA-binding protein regions in human cells
Species: Homo sapiens (Human)
Project description: Idenfication of RNA-binding regions in human proteins using pCLA (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-06-18
Induction by Bradyrhizobium diazoefficiens of different catabolic pathways for growth in D-mannitol or L-arabinose leading to pronounced differences in CO2 fixation, O2 consumption, and lateral-flagellum production
Species: Bradyrhizobium japonicum USDA 110
Project description: Bradyrhizobium diazoefficiens, the soybean N2-fixing symbiont, u (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-06-25
Protein interactome of small RNA fragments: identification and functional implications
Species: Homo sapiens (Human)
Project description: Populations of small eukaryotic RNAs, in addition to relatively (More)
Diseases: disease free
Quantification method: Label free
Made public: 2018-10-24
Identification of potential human PML interacting proteins in Nicotiana benthamiana
Species: Nicotiana benthamiana
Project description: In spite of the crucial tasks fulfilled by the subnuclear struct (More)
Diseases: disease free
Quantification method: Label free
Made public: 2016-10-10
Comparative proteome stability analysis of snap frozen, RNAlater preserved, and formalin-fixed paraffin-embedded human colon mucosal biopsies
Species: Homo sapiens (Human)
Project description: preservation method on the result of a proteome analysis was characterized by high throughput gel free (More)
Diseases: disease free
Quantification method: Label free
Made public: 2015-11-23
Substrate identification of ADAMTS16
Species: Homo sapiens (Human) Mus musculus (Mouse)
Project description: using cell free ECM produced by mouse Balb/c 3T3 cells in vitro to identify fibronectin as a novel (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2018-04-23
The proteome of native adult Müller cells from the murine retina
Species: Mus musculus (Mouse)
Project description: various retinal cell types and Müller cells as key players in health and ultimately also under disease (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2016-08-15
Galectin-1 and Galectin-3 interactors
Species: Homo sapiens (Human)
Project description: Galectin-1 (Gal-1) and Galectin-3 (Gal-3) in context of the eye disease proliferative vitreoretinopathy (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2017-06-06
Profiling of Human Circulating Plasma Microparticle Associated Proteins by DDA and DIA
Species: Homo sapiens (Human)
Project description: health and disease. Furthermore, MP have intercellular communication/signaling properties and interfere (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2016-10-18
Function of CK2-alpha in a minimal circadian system
Species: Ostreococcus tauri
Project description: Casein Kinase 2 (CK2) is an evolutionarily conserved kinase prot (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2015-08-11
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons
Species: Rattus norvegicus (Rat)
Project description: Whole proteome quantification identified upregulation of the ESC (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2016-09-29
Protein abundance of AKT and ERK pathway components governs cell-type-specific regulation of proliferation
Species: Homo sapiens (Human)
Project description: Signaling through the AKT and ERK pathways controls cell prolife (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2017-01-30
Salivary proteomics of sP and sNP rats
Species: Rattus norvegicus (Rat)
Project description: Sardinian alcohol-preferring (sP) and Sardinina alcohol-non pref (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2017-11-03
Effect of Sec61 inhibitor mycolactone on the proteome of the MutuDC dendritic cell line
Species: Mus musculus (Mouse)
Project description: Here we used a newly identified Sec61 blocker, mycolactone, to a (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2017-07-11
Proteome allocation strategies under nutrient-limiting conditions in the cyanobacterium Synechocystis
Species: Synechocystis sp. PCC 6803 substr. GT-S
Project description: The response of the model cyanobacterium Synechocystis sp. PCC68 (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2018-09-12
Fam49/CYRI interacts with Rac1 and locally suppresses protrusions
Species: Dictyostelium discoideum (Slime mold)
Project description: Actin-based protrusions driving cell migration are reinforced th (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2018-10-08
Salt stress phosphorylation network
Species: Saccharomyces cerevisiae (Baker's yeast)
Project description: We utilized high resolution, high mass accuracy quantitative pro (More)
Diseases: disease free
Quantification method: MS1 intensity based label-free quantification method
Made public: 2018-04-05
The gut microbiota affects the mucus barrier
Species: Mus musculus (Mouse)
Project description: Two C57BL/6 mice colonies maintained in two rooms in the same specific pathogen free (SPF) facility (More)
Diseases: disease free
Made public: 2015-02-09
S. aciditrophicus
Species: Syntrophus aciditrophicus
Project description: We utilize a harsh mass-spectrometry compatible sample preparation method (eFASP), and label-free (More)
Diseases: disease free
Made public: 2017-07-28
Proteome profiling of Rhodobacter capsulatus wild type and a ΔmodABC mutant in response to molybdenum
Species: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Project description: molybdenum-dependent and an alternative Mo-free iron-only nitrogenase, enabling growth with molecular (More)
Diseases: disease free
Made public: 2015-12-14
SuperQuant: a Data Processing Approach to Increase Quantitative Proteome Coverage
Species: Homo sapiens (Human)
Project description: complementarity to identify multiple co-isolated peptides in tandem mass spectra. Parent ion and label-free (More)
Diseases: disease free
Made public: 2015-05-26
LC-MS/MS analysis of soluble lysosomal enzymes
Species: Mus musculus (Mouse)
Project description: progressive destruction of hip joints. The disease is caused by mutations in GNPTG encoding the gamma-subunit (More)
Diseases: disease free
Made public: 2018-06-07
The human amyloid beta peptide interactome
Species: Homo sapiens (Human)
Project description: understood to play a critical role in Alzheimer’s disease (AD). The primary objective of this study was to (More)
Diseases: disease free
Made public: 2017-07-05
Urinary polypeptide ETD/CID analysis, part 2
Species: Homo sapiens (Human)
Project description: disease. In this study, we examine the urinary peptidome from normal healthy women during pregnancy, to (More)
Diseases: disease free
Made public: 2016-02-15
Urinary polypeptide ETD/CID analysis, part 3
Species: Homo sapiens (Human)
Project description: disease. In this study, we examine the urinary peptidome from normal healthy women during pregnancy, and (More)
Diseases: disease free
Made public: 2016-02-15
Urinary polypeptide ETD/CID analysis, part 1
Species: Homo sapiens (Human)
Project description: disease. In this study, we examine the urinary peptidome from normal healthy women during pregnancy, to (More)
Diseases: disease free
Made public: 2016-02-15
Maize seedling root cells LC-MS/MS
Species: Zea mays (Maize)
Project description: metabolism, energy, disease/defense and transport. In the tolerant line A3237, NADP-malic enzyme, glutamate (More)
Diseases: disease free
Made public: 2014-11-18
DONSON encodes a novel replication fork protection factor mutated in 2 microcephalic dwarfism.
Species: Homo sapiens (Human)
Project description: impair fork stability in patient cells, consistent with defective DNA replication underlying the disease (More)
Diseases: disease free
Made public: 2017-02-10
LC-MS/MS analysis of Mannose 6-phosphate containing proteins
Species: Mus musculus (Mouse)
Project description: progressive destruction of hip joints. The disease is caused by mutations in GNPTG encoding the gamma-subunit (More)
Diseases: disease free
Made public: 2018-06-06
Proteome Comparison of Different-Aged Cochlea
Species: Mus musculus (Mouse)
Project description: Our work describes the application of mass spectrometry-based label-free quantitative proteomics (More)
Diseases: disease free
Made public: 2018-08-29
Global protein oxidation profiling suggests efficient mitochondrial proteome homeostasis during ageing
Species: Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina)
Project description: The free radical theory of ageing is based on the idea that reactive oxygen species (ROS) may lead (More)
Diseases: disease free
Made public: 2016-02-24
Proteomic Identification of Nuclear Processes Manipulated by Cytomegalovirus Early during Infection
Species: Human cytomegalovirus (HHV-5) (Human herpesvirus 5) Homo sapiens (Human)
Project description: causes life-threating disease upon immunosuppression. HCMV expresses numerous proteins that function to (More)
Diseases: disease free
Made public: 2015-06-23
SILAC-Based Proteomics of Primary Human Kidney Cells treated with Sex Hormones.
Species: Homo sapiens (Human)
Project description: deleterious effects of androgens in the context of kidney disease, especially diabetic nephropathy. (More)
Diseases: disease free
Made public: 2017-01-17
Protein interaction networks for Matrin 3 encoding mutations
Species: Homo sapiens (Human)
Project description: MATR3 with disease-causing mutations is not dramatically different from WT protein in modulating gene (More)
Diseases: disease free
Made public: 2018-08-03

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