PDBsum entry 9wzc

Immune system

PDB id: 9wzc

Contents

Protein chains

(+ 6 more) 83 a.a.

PDB id:

9wzc

Name:

Immune system

Title:

R41e-asc card filament

Structure:

Apoptosis-associated speck-like protein containing a card. Chain: a, b, c, d, e, f, g, h, i, j, k, l. Synonym: hasc,caspase recruitment domain-containing protein 5,pyd and card domain-containing protein,target of methylation-induced silencing 1. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pycard, asc, card5, tms1. Expressed in: homo sapiens. Expression_system_taxid: 9606

Authors:

D.Xue,F.Ni,S.Liu,H.Yan,Z.Luo,G.Fu,Q.Wang,J.Ma

Key ref:

D.Xue et al. (2025). Atomic mechanisms of full-Length asc-Mediated inflamm assembly.. Nat commun, 16, 10564. PubMed id: 41298390 DOI: 10.1038/S41467-025-65578-2

Date:

29-Sep-25 Release date: 10-Dec-25

Protein chains

Q9ULZ3  (ASC_HUMAN) -  Apoptosis-associated speck-like protein containing a CARD from Homo sapiens

Seq: 195 a.a.

Struc: 83 a.a.